Welfare Assessment

Affective state determination in a mouse model of colitis-associated colorectal cancer

Behavioural indicators of affective state, including burrowing, clinical scores and the Mouse Grimace Score have not yet been validated in mouse models of chronic gastrointestinal disease. Additionally, a comparison of these methods has not been characterised. This study aimed to...

Year Published: 2020Topics: Disease/Experimental Model, Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Chartier, L. C., Hebart, M. L., Howarth, G. S. et al. 2020. Affective state determination in a mouse model of colitis-associated colorectal cancer. PLOS ONE 15(1), e0228413.

Animal welfare assessment protocol for does, bucks, and kit rabbits reared for production

Rabbits are the third species in terms of number of animals reared for meat production in the world. However, in comparison to other species, very few studies have focused on their welfare. The aim of the present study is to...

Year Published: 2020Topics: Welfare AssessmentAnimal Type: Rabbit

Citation: Dalmau, A., Moles, X., Pallisera, J. 2020. Animal welfare assessment protocol for does, bucks, and kit rabbits reared for production. Frontiers in Veterinary Science 7, 445.

Assessing pain in models of rheumatoid arthritis

A hallmark symptom of rheumatoid arthritis in humans is painful swollen joints. Pain can manifest before any inflammation is noticeable as well as persist long after inflammation has resolved. In rodent models of arthritis, ankle or footpad width is a...

Year Published: 2020Topics: Disease/Experimental Model, Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Singleton, S., Nefla, M., Dennison, N. et al. 2020. Assessing pain in models of rheumatoid arthritis. Animal Technology and Welfare 19(2), 149-152.

Behavioral diversity as a potential indicator of positive animal welfare

Modern day zoos and aquariums continuously assess the welfare of their animals and use evidence to make informed management decisions. Historically, many of the indicators of animal welfare used to assess the collection are negative indicators of welfare, such as...

Year Published: 2020Topics: Natural Behavior, Welfare AssessmentAnimal Type: All/General, Amphibian, Nonhuman Primate, Reptile

Citation: Miller, L. J., Vicino, G. A., Sheftel, J. et al. 2020. Behavioral diversity as a potential indicator of positive animal welfare. Animals 10(7), 1211.

Behavioral methods for severity assessment

It has become mandatory for the application for allowance of animal experimentation to rate the severity of the experimental procedures. In order to minimize suffering related to animal experimentation it is therefore crucial to develop appropriate methods for the assessment...

Year Published: 2020Topics: Welfare AssessmentAnimal Type: All/General

Citation: Kahnau, P., Habedank, A., Diederich, K. et al. 2020. Behavioral methods for severity assessment. Animals 10(7), 1136.

Comparing distress of mouse models for liver damage

In order to foster animal welfare as well as high quality of research, many countries regulate by law that the severity of animal experiments must be evaluated and considered when performing biomedical research. It is well accepted that multiple parameters...

Year Published: 2020Topics: Disease/Experimental Model, Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Tang, G., Seume, N., Häger, C. et al. 2020. Comparing distress of mouse models for liver damage. Scientific Reports 10(1), 19814.

Defining body-weight reduction as a humane endpoint: A critical appraisal

In many animal experiments scientists and local authorities define a body-weight reduction of 20% or more as severe suffering and thereby as a potential parameter for humane endpoint decisions. In this study, we evaluated distinct animal experiments in multiple research...

Year Published: 2020Topics: Disease/Experimental Model, Humane Endpoint, Welfare AssessmentAnimal Type: Mouse, Rat, Rodent

Citation: Talbot, S. R., Biernot, S., Bleich, A. et al. 2020. Defining body-weight reduction as a humane endpoint: A critical appraisal. Laboratory Animals 54(1), 99–110.

Design of composite measure schemes for comparative severity assessment in animal-based neuroscience research: A case study focussed on rat epilepsy models

Comparative severity assessment of animal models and experimental interventions is of utmost relevance for harm-benefit analysis during ethical evaluation, an animal welfare-based model prioritization as well as the validation of refinement measures. Unfortunately, there is a lack of evidence-based approaches...

Year Published: 2020Topics: Disease/Experimental Model, Welfare AssessmentAnimal Type: Rat, Rodent

Citation: van Dijk, R. M., Koska, I., Bleich, A. et al. 2020. Design of composite measure schemes for comparative severity assessment in animal-based neuroscience research: A case study focussed on rat epilepsy models. PLOS ONE 15(5): e0230141.

Developing an animal welfare assessment protocol for cows in extensive beef cow-calf systems in New Zealand

The intention of this study was to develop standards for a welfare assessment protocol by validating potential categorisation thresholds for the assessment of beef farms in New Zealand. Thirty-two measures, based on the Welfare Quality and the University of California...

Year Published: 2020Topics: Welfare AssessmentAnimal Type: Cattle

Citation: Kaurivi, Y. B., Hickson, R., Laven, R. et al. 2020. Developing an animal welfare assessment protocol for cows in extensive beef cow-calf systems in New Zealand. Part 2: Categorisation and scoring of welfare assessment measures. Animals 10(9), 1592.

Developing an animal welfare assessment protocol for cows in extensive beef cow–calf systems in New Zealand

Potential measures suitable for assessing welfare in pasture-based beef cow–calf systems in New Zealand were identified from Welfare Quality and UC Davis Cow-Calf protocols. These were trialled on a single farm and a potential protocol of 50 measures created. The...

Year Published: 2020Topics: Welfare AssessmentAnimal Type: Cattle

Citation: Kaurivi, Y. B., Laven, R., Hickson, R. et al. 2020. Developing an animal welfare assessment protocol for cows in extensive beef cow–calf systems in New Zealand. Part 1: Assessing the feasibility of identified animal welfare assessment measures. Animals 10(9), 1597.