Rat

Report of the 2024 RSPCA/UFAW rodent welfare group meeting

The RSPCA/UFAW Rodent Welfare Group has held a one-day meeting every autumn for the last 31 years. These meetings provide an opportunity for members to discuss current welfare research, exchange views on welfare issues and share their experiences of the...

Year Published: 2025Topics: Animal Training, Drug/Substance Administration, Environmental Enrichment, Handling, Housing, Husbandry & Management, Imaging & Electrophysiological RecordingAnimal Type: Mouse, Rabbit, Rat, Rodent

Citation: Stevens, C., Robinson, E., Jackson, M. et al. 2025. Report of the 2024 RSPCA/UFAW rodent welfare group meeting. Animal Welfare and Technology 4(3), 219–226.

Assessment of behavioral, clinical, and histological outcomes in Sprague-Dawley rats housed in enriched colony cages versus conventional pair housing over 28 days

The standardization of husbandry in animal studies for drug development aims to minimize variability and enhance inter-laboratory comparability. Rats are a commonly used species in such studies. This standardization yields housing conditions that do not reflect the natural environment of...

Year Published: 2025Topics: Environmental Enrichment, HousingAnimal Type: Rat, Rodent

Citation: Shamsi, A., Niebl, P., Kalina, A. et al. 2025. Assessment of behavioral, clinical, and histological outcomes in Sprague-Dawley rats housed in enriched colony cages versus conventional pair housing over 28 days. Animals 15(24).

Video based heart rate detection in unrestrained laboratory rats: A feasibility analysis

Continuous monitoring of vital signs in laboratory animals is often essential for reliable scientific results and severity assessment. It still depends on invasive approaches such as transponder implementation, which affect the animals well-being. To minimize this impact, a camera-based method...

Year Published: 2025Topics: Biological Sampling & Physiological MeasurementAnimal Type: Rat, Rodent

Citation: Monissen, J., Mösch, L., Monissen, M. et al. 2025. Video based heart rate detection in unrestrained laboratory rats: A feasibility analysis. Scientific Reports 15(1), 37935.

The edge of lesion

At AstraZeneca we utilise a wide variety of flank tumour models in rodents to gather data on the effectiveness of our Oncology drugs. During these studies tumour condition is closely monitored for appearance of lesions; typically a change of shape...

Year Published: 2025Topics: Humane EndpointAnimal Type: Rat, Rodent

Citation: Little, E., Baker, T., Peverill, J. et al. 2025. The edge of lesion. Animal Technology and Welfare 24(3), 268–269.

Adaptation of the Animal Welfare assessment grid (AWAG) model to monitor laboratory rats and mice

The Animal Welfare assessment grid (AWAG) is a cloud based online tool designed to assess and monitor the welfare and cumulative lifetime experience of animals. It has been successfully used to monitor the wellbeing of animals from an experimental, zoological,...

Year Published: 2025Topics: Welfare AssessmentAnimal Type: Mouse, Rat, Rodent

Citation: Cunningham, A., Wolfensohn, S., Dennis, M. et al. 2025, December. Adaptation of the Animal Welfare assessment grid (AWAG) model to monitor laboratory rats and mice. Animal Technology and Welfare 4(3), 199–211.

Rat boredom-like behaviour in a monotonous versus a varied foraging task: Effects of sensory variation

Evidence increasingly reveals that non-human animals in monotonous situations can show boredom-like states, distinctively manifesting as increases in both arousal-seeking, restless behaviour and low arousal, drowsy behaviour. However, task related boredom has been little investigated in animals, but could have...

Year Published: 2025Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Burn, C. C., Ng, K. H. T., Parker, M. O. 2025. Rat boredom-like behaviour in a monotonous versus a varied foraging task: Effects of sensory variation. Animal Cognition 28(1), 57.

Refining the adjuvant-induced rat model of monoarthritis by optimizing the induction volume and injection site

Arthritis is a highly prevalent and disabling condition characterized by pathological joint-damage, clinical symptoms of pain and loss of normal joint function. Monoarthritis can be modelled in rodents via intraarticular injection of Complete Freund’s Adjuvant (CFA), inducing both joint inflammation...

Year Published: 2025Topics: Disease/Experimental ModelAnimal Type: Rat, Rodent

Citation: Berke, M. S., Hansen, C. P., Kromann, S. et al. 2025. Refining the adjuvant-induced rat model of monoarthritis by optimizing the induction volume and injection site. Scientific Reports 15(1), 40281.

A review of pain assessment methods in laboratory rodents

Ensuring that laboratory rodent pain is well managed underpins the ethical acceptability of working with these animals in research. Appropriate treatment of pain in laboratory rodents requires accurate assessments of the presence or absence of pain to the extent possible....

Year Published: 2020Topics: Welfare AssessmentAnimal Type: Chinchilla, Gerbil, Guinea Pig, Hamster, Mouse, Other Rodent, Rat, Rodent

Citation: Turner, P. V., Pang, D. S., Lofgren, J. L. 2019. A review of pain assessment methods in laboratory rodents. Comparative Medicine 69(6), 451–467.

What is your tattoo ink telling you?

Tattooing traumatizes the skin, which can result in microbial infections with the severity ranging from minor to life-threating septicemia. Additionally, the metals in colored tattoo ink are known to cause dermal inflammation in some people. In the laboratory animal research...

Year Published: 2020Topics: Identification MethodAnimal Type: All/General, Mouse, Rat, Rodent

Citation: Young, T., Whiteside, T., Locklear, J. 2020. What is your tattoo ink telling you? Laboratory Animal Science Professional 8(2) (March/April), 62-65.

Similar levels of emotional contagion in male and female rats

Emotional contagion, the ability to feel what other individuals feel without necessarily understanding the feeling or knowing its source, is thought to be an important element of social life. In humans, emotional contagion has been shown to be stronger in...

Year Published: 2020Topics: Emotion, Pain, & SentienceAnimal Type: Rat, Rodent

Citation: Han, Y., Sichterman, B., Maria, C. et al. 2020. Similar levels of emotional contagion in male and female rats. Scientific Reports 10(1), 2763.