Euthanasia

Review of rodent euthanasia methods

The optimal choice of euthanasia method for laboratory rodents depends on a number of factors, including the scientific goals of the study, the need to minimize animal pain and/or distress, applicable guidelines and laws, the training and proficiency of personnel,...

Year Published: 2020Topics: EuthanasiaAnimal Type: Guinea Pig, Hamster, Mouse, Rat, Rodent

Citation: Shomer, N. H., Allen-Worthington, K. H., Hickman, D. L. et al. 2020. Review of rodent euthanasia methods. JAALAS 59(3), 242–253.

The cotton rat – a new challenge

This poster describes how the Animal Technologists at Envigo adapted their current practices and procedures for a new species at their laboratory: the cotton rat. The paper describes cotton rat biology and behaviour; housing; environmental enrichment; health; dosing and blood...

Year Published: 2020Topics: Anesthesia & Sedation, Biological Sampling & Physiological Measurement, Drug/Substance Administration, Environmental Enrichment, Euthanasia, Housing, Husbandry & Management, Natural BehaviorAnimal Type: Rat, Rodent

Citation: Ballantine, A., Rodgers, D., Watts, C. et al. 2020. The cotton rat – a new challenge. Animal Technology and Welfare 19(1), 92-95.

A systematic literature review on depopulation methods for swine

Swine mass depopulation refers to the destruction of large numbers of pigs and may include not only animals affected with a disease but also healthy pigs in a facility or surrounding areas. Emerging applications of mass depopulation include reducing welfare...

Year Published: 2020Topics: EuthanasiaAnimal Type: Pig

Citation: Arruda, A. G., Beyene, T. J., Kieffer, J. et al. 2020. A systematic literature review on depopulation methods for swine. Animals 10(11), 2161.

Aversion to desflurane and isoflurane in Sprague-Dawley rats (Rattus norvegicus)

Carbon dioxide and isoflurane are widely used for killing rats, yet may not truly achieve “euthanasia”, because they elicit aversion. The inhalant anesthetic desflurane is faster acting than isoflurane, representing a potential refinement. Using an aversion-avoidance paradigm, 24 rats were...

Year Published: 2020Topics: EuthanasiaAnimal Type: Rat, Rodent

Citation: Frost, K., Shah, M., Leung , V. S. Y. et al. 2020. Aversion to desflurane and isoflurane in Sprague-Dawley rats (Rattus norvegicus). Animals 10(6), 950.

Behavioral and corticosterone responses to carbon dioxide exposure in reptiles

The use of carbon dioxide (CO2) exposure as a means of animal euthanasia has received considerable attention in mammals and birds but remains virtually untested in reptiles. We measured the behavioral responses of four squamate reptile species (Homalopsis buccata, Malayopython...

Year Published: 2020Topics: EuthanasiaAnimal Type: Lizard, Reptile, Snake

Citation: Natusch, D. J. D., Aust, P. W., Khadiejah, S. et al. 2020. Behavioral and corticosterone responses to carbon dioxide exposure in reptiles. PLOS ONE 15(10), e0240176.

Behavioral response of weaned pigs during gas euthanasia with CO2, CO2 with butorphanol, or nitrous oxide

The swine industry is often forced to euthanize pigs in the first few weeks of life due to injuries, hernias, or unthriftiness. The majority of pigs are euthanized using carbon dioxide (CO2) gas asphyxiation but concerns as to the humaneness...

Year Published: 2020Topics: EuthanasiaAnimal Type: Pig

Citation: Çavuşoğlu, E., Rault, J.-L., Gates, R. et al. 2020. Behavioral response of weaned pigs during gas euthanasia with CO2, CO2 with butorphanol, or nitrous oxide. Animals 10(5), 787.

Effect of two different stunning methods on the quality traits of rabbit meat

The aim of the study was to assess the effect of two different stunning methods on the level of blood stress indicators (cortisol, insulin, glucose) and rabbit meat quality. The experiment was conducted on crossbreds of Hycole, Hyla, and Jordan...

Year Published: 2020Topics: EuthanasiaAnimal Type: Rabbit

Citation: Składanowska-Baryza, J., Ludwiczak, A., Pruszyńska-Oszmałek, E. et al. 2020. Effect of two different stunning methods on the quality traits of rabbit meat. Animals 10(4), 700.

Evaluating intrahepatic and intraperitoneal sodium pentobarbital or ethanol for mouse euthanasia

Intraperitoneal (IP) injection of sodium pentobarbital (PB) is an accepted method of euthanasia for mice. However, this method has important drawbacks, including the potential for pain or misinjection. The objective of this prospective, randomized, blinded study was to determine whether...

Year Published: 2020Topics: EuthanasiaAnimal Type: Mouse, Rodent

Citation: Laferriere, C. A., Leung, V. S., Pang, D. S. 2020. Evaluating intrahepatic and intraperitoneal sodium pentobarbital or ethanol for mouse euthanasia. JAALAS 59(3), 264–268.

Evaluation of effective and practical euthanasia methods for larval African clawed frogs (Xenopus laevis)

Larval, or tadpole-stage Xenopus laevis frogs are a popular research model for developmental biology and disease studies. Existing euthanasia guidance documents offer recommendations for both eggs and adult stages, yet do not specifically address the larval stage. Data evaluating effective...

Year Published: 2020Topics: EuthanasiaAnimal Type: Amphibian, Frog & Toad

Citation: Galex, I. A., Gallant, C. M., D'Avignon, N. et al. 2020. Evaluation of effective and practical euthanasia methods for larval African clawed frogs (Xenopus laevis). JAALAS 59(3), 269–274.

Humane euthanasia of guinea pigs (Cavia porcellus) with a penetrating spring-loaded captive bolt

Guinea pigs (Cavia porcellus) have been used in research since the 19th century to collect data due to their physiological similarities to humans. Today, animals perform a vital role in experiments and concerns for laboratory animal welfare are enshrined in...

Year Published: 2020Topics: EuthanasiaAnimal Type: Guinea Pig, Rodent

Citation: Cohen, S., Kwok, M., Huang, J. 2020. Humane euthanasia of guinea pigs (Cavia porcellus) with a penetrating spring-loaded captive bolt. Animals 10(8), 1356.