Publications

Effect of aggressive experience in female Syrian hamsters on glutamate receptor expression in the nucleus accumbens

Our social relationships determine our health and well-being. In rodent models, there is now strong support for the rewarding properties of aggressive or assertive behaviors to be critical for the expression and development of adaptive social relationships, buffering from stress...

Year Published: 2020Topics: Natural BehaviorAnimal Type: Hamster, Rodent

Citation: Borland, J. M., Kim, E., Swanson, S. P. et al. 2020. Effect of aggressive experience in female Syrian hamsters on glutamate receptor expression in the nucleus accumbens. Frontiers in Behavioral Neuroscience 14, 583395.

Effects of weaning age and housing conditions on phenotypic differences in mice

Poor reproducibility is considered a serious problem in laboratory animal research, with important scientific, economic, and ethical implications. One possible source of conflicting findings in laboratory animal research are environmental differences between animal facilities combined with rigorous environmental standardization within...

Year Published: 2020Topics: Rearing & WeaningAnimal Type: Mouse, Rodent

Citation: Bailoo, J. D., Voelkl, B., Varholick, J. et al. 2020. Effects of weaning age and housing conditions on phenotypic differences in mice. Scientific Reports 10, 11684.

Eliminating light-at-night contamination during a lab animal facility renovation

Relocating laboratory animal research from one animal facility room to another in advance of major renovations can be a daunting task for scientists and animal care personnel alike. This is especially so regarding controlled lighting and the elimination of light-at-night...

Year Published: 2020Topics: Husbandry & ManagementAnimal Type: Chinchilla, Gerbil, Guinea Pig, Hamster, Mouse, Other Rodent, Rat, Rodent

Citation: Dupepe, L. M., Dauchy, R. T., McAndrew, D. et al. 2020. Eliminating light-at-night contamination during a lab animal facility renovation. Laboratory Animal Science Professional 8(5) (September/October), 60-62.

Emotion recognition in cats

Recent studies demonstrated that cats form social bonds with both conspecifics and humans. One of the key factors regulating social interactions is the transfer of emotions between the individuals. The present study aimed at investigating cats’ spontaneous ability to match...

Year Published: 2020Topics: Human-Animal InteractionAnimal Type: Cat

Citation: Quaranta, A., d’Ingeo, S., Amoruso, R. et al. 2020. Emotion recognition in cats. Animals 10(7), 1107.

Endpoint in ovarian cancer xenograft model predicted by nighttime motion metrics

Despite several therapeutics showing promise in nonclinical studies, survival from ovarian cancer remains poor. New technologies are urgently needed to optimize the translation of nonclinical studies into clinical successes. While most nonclinical settings utilize subjective measures of physiological parameters, which...

Year Published: 2020Topics: Disease/Experimental Model, Humane EndpointAnimal Type: Mouse, Rodent

Citation: Nwagwu, C. D., Defensor, E., Jiang, M. Y. et al. 2020. Endpoint in ovarian cancer xenograft model predicted by nighttime motion metrics. Lab Animal 49(8), 227–232.

Enriched environment effect on lipopolysaccharide-induced spatial learning, memory impairment and hippocampal inflammatory cytokine levels in male rats

Neuro-inflammation is responsible for cognitive impairments and neurodegenerative diseases such as Alzheimer’s disease. In this study, we aimed to investigate the enriched environment (EE) effect on learning and memory impairment as well as on pro-inflammatory cytokines changes induced by lipopolysaccharide...

Year Published: 2020Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Keymoradzadeh, A., Hedayati Ch, M., Abedinzade, M. et al. 2020. Enriched environment effect on lipopolysaccharide-induced spatial learning, memory impairment and hippocampal inflammatory cytokine levels in male rats. Behavioural Brain Research 394, 112814.

Enriched environment exposure accelerates rodent driving skills

Although rarely used, long-term behavioral training protocols provide opportunities to shape complex skills in rodent laboratory investigations that incorporate cognitive, motor, visuospatial and temporal functions to achieve desired goals. In the current study, following preliminary research establishing that rats could...

Year Published: 2020Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Crawford, L. E., Knouse, L. E., Kent, M. et al. 2020. Enriched environment exposure accelerates rodent driving skills. Behavioural Brain Research 378, 112309.

Enriched environments enhance cognition, exploratory behaviour and brain physiological functions of Sparus aurata

Environmental enrichment is considered as a recommended tool to guarantee or improve the welfare of captive fish. This study demonstrates for the first time that structural environmental enrichment enhances cognition, exploratory behaviour and brain physiological functions of gilthead seabream (Sparus...

Year Published: 2020Topics: Environmental EnrichmentAnimal Type: Fish, Other Fish

Citation: Arechavala-Lopez, P., Caballero-Froilán, J. C., Jiménez-García, M. et al. 2020. Enriched environments enhance cognition, exploratory behaviour and brain physiological functions of Sparus aurata. Scientific Reports 10, 11252.

Evaluation of subcutaneous administration of alfaxalone-midazolam and ketamine-midazolam as sedation protocols in African pygmy hedgehogs (Atelerix albiventris)

OBJECTIVE: To evaluate SC administration of 2 sedation protocols, ketamine-midazolam (KM) and alfaxalone-midazolam (AM), in African pygmy hedgehogs (Atelerix albiventris). ANIMALS: 9 healthy adult hedgehogs (5 males, 4 females). PROCEDURES: A randomized, blinded, complete crossover study was performed. Sedation was...

Year Published: 2020Topics: Anesthesia & SedationAnimal Type: Other Animal

Citation: Hawkins, S. J., Doss, G. A., Mans, C. 2020. Evaluation of subcutaneous administration of alfaxalone-midazolam and ketamine-midazolam as sedation protocols in African pygmy hedgehogs (Atelerix albiventris). Journal of the American Veterinary Medical Association 257(8), 820-825.

Evaluation of the physical properties of bedding materials for dairy cattle using fuzzy clustering analysis

The bedding materials used in dairy cow housing systems are extremely important for animal welfare and performance. A wide range of materials can be used as bedding for dairy cattle, but their physical properties must be analysed to evaluate their...

Year Published: 2020Topics: Husbandry & ManagementAnimal Type: Cattle

Citation: Ferreira Ponciano Ferraz, P., Araújo e Silva Ferraz, G., Leso, L. et al. 2020. Evaluation of the physical properties of bedding materials for dairy cattle using fuzzy clustering analysis. Animals 10(2), 351.