Publications

Assessing the severity of laparotomy and partial hepatectomy in male rats—A multimodal approach

This study assessed the postoperative severity after three different visceral surgical interventions in rats by using objective parameters pertaining to various disciplines. The objective was to evaluate whether the degree of severity increases with the invasiveness of the intervention and...

Year Published: 2021Topics: Welfare AssessmentAnimal Type: Rat, Rodent

Citation: Zieglowski, L., Kümmecke, A. M., Ernst, L. et al. 2021. Assessing the severity of laparotomy and partial hepatectomy in male rats—A multimodal approach. PLOS ONE 16(8), e0255175.

Perceptions of laboratory animal facility managers regarding institutional transparency

Institutions that conduct animal research are often obliged to release some information under various legal or regulatory frameworks. However, within an institution, perspectives on sharing information with the broader public are not well documented. Inside animal facilities, managers exist at...

Year Published: 2021Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Brunt, M. W., Weary, D. M. 2021. Perceptions of laboratory animal facility managers regarding institutional transparency. PLOS ONE 16(7), e0254279.

Evaluation of an enrichment programme for a colony of long-tailed macaques (Macaca fascicularis) in a rescue centre

Long-tailed macaques are highly social primates that are commonly used in biomedical research as animal models. The aim of this study was to evaluate the effects of different kinds of enrichment on the behaviour and faecal cortisol metabolite (FCM) level...

Year Published: 2021Topics: Environmental EnrichmentAnimal Type: Macaque, Nonhuman Primate

Citation: Albanese, V., Kuan, M., Accorsi, P.A. et al. 2021. Evaluation of an enrichment programme for a colony of long-tailed macaques (Macaca fascicularis) in a rescue centre. Primates 62(4), 585-593.

Physiological variation in Japanese macaques (Macaca fuscata) housed in different outdoor cages evaluated using the metabolic profile test

Captive primates require environmental enrichment to minimize physical and mental stress. However, only a few objective evaluations have been performed to assess environment-induced physiological variations in these animals. In this study, we evaluated the usage of the metabolic profile test...

Year Published: 2021Topics: HousingAnimal Type: Macaque, Nonhuman Primate

Citation: Kaneko, A., Takasu, M., Miyabe-Nishiwaki, T. et al. 2021. Physiological variation in Japanese macaques (Macaca fuscata) housed in different outdoor cages evaluated using the metabolic profile test. Primates 62(4), 609-615.

The effects of bedding material on the treatment of mild pododermatitis in the guinea pig (Cavia porcellus)

One of our colony's five guinea pigs started to develop a moderate case of pododermatitis (bumblefoot) on one paw, which staff were keen to alleviate to prevent any detrimental effects that this might have on her health and welfare. Pododermatitis...

Year Published: 2021Topics: Husbandry & ManagementAnimal Type: Guinea Pig, Rodent

Citation: Ferguson, K., Fisher, Z. 2021. The effects of bedding material on the treatment of mild pododermatitis in the guinea pig (Cavia porcellus). RATEL (Journal of the Association of British and Irish Wild Animal Keepers) 48(1), 18-22.

A novel model of ischemia in rats with middle cerebral artery occlusion using a microcatheter and zirconia ball under fluoroscopy

Here, we present a highly selective rat MCAO model by percutaneous caudal arterial puncture using a microcatheter and zirconia ball under fluoroscopic guidance. The model is predictable and reproducible, which is well confined within the territory supplied by the MCA,...

Year Published: 2021Topics: Disease/Experimental ModelAnimal Type: Rat, Rodent

Citation: Komatsu, T., Ohta, H., Motegi, H. et al. 2021. A novel model of ischemia in rats with middle cerebral artery occlusion using a microcatheter and zirconia ball under fluoroscopy. Scientific Reports 11(1), 12806.

Rearing experience with ramps improves specific learning and behaviour and welfare on a commercial laying farm

To access resources in commercial laying houses hens must move between levels with agility to avoid injury. This study considered whether providing ramps during rear improved the ability of birds to transition between levels. Twelve commercial flocks (2000 birds/flock) on...

Year Published: 2021Topics: Environmental Enrichment, Husbandry & ManagementAnimal Type: Bird, Chicken

Citation: Norman, K. I., Weeks, C. A., Tarlton, J. F. 2021. Rearing experience with ramps improves specific learning and behaviour and welfare on a commercial laying farm. Scientific Reports 11(1), 8860.

The impact of a stress-reducing protocol on the quality of pre-anaesthesia in cats

Introduction: Transport to the clinic is a major source of stress for cats. The process involves being put into a carrier, driven in a car and handled. Cats are therefore removed from the safe-haven of their territory and experience many...

Year Published: 2021Topics: Anesthesia & Sedation, Handling, Relocation & TransportAnimal Type: Cat

Citation: Argüelles, J., Echaniz, M., Bowen, J. et al. 2021. The impact of a stress-reducing protocol on the quality of pre-anaesthesia in cats. Veterinary Record 188(12), e138.

Comparison of pain response after subcutaneous injection of two maropitant formulations to beagle dogs

The antiemetic maropitant, with metacresol as preservative (Cerenia, Zoetis), has been associated with pain after subcutaneous injection in dogs and cats. Recently, a generic formulation containing benzyl alcohol was authorised (Prevomax, Le Vet). Benzyl alcohol is reported to have local...

Year Published: 2018Topics: Drug/Substance AdministrationAnimal Type: Dog

Citation: Deckers, N., Ruigrok, C. A., Verhoeve, H. P. et al. 2018. Comparison of pain response after subcutaneous injection of two maropitant formulations to beagle dogs. Veterinary Record Open 5(1), e000262.

Analgesic effects of intravenous flunixin and intrafunicular lidocaine or their combination for castration of lambs

Objective: To analyse the effectiveness of intrafunicular lidocaine and intravenous flunixin for reducing pain and signs of stress in lambs undergoing surgical castration. Design: Randomised controlled trial. Setting: One university teaching hospital in Italy. Participants: 30 healthy male lambs, 9–12...

Year Published: 2018Topics: Analgesia, Body Modification/MutilationAnimal Type: Sheep

Citation: Straticò, P., Varasano, V., Suriano, R. et al. 2018. Analgesic effects of intravenous flunixin and intrafunicular lidocaine or their combination for castration of lambs. Veterinary Record Open 5(1), e000266.