Publications

Vivarium lighting and the new measurement metrics

In February 2023, a workshop entitled The 3rd International Workshop on Circadian and Neurophysiological Photometry was held in Manchester, UK to address the problem of light measurement in laboratory animal research. This workshop resulted in a consensus view of an...

Year Published: 2023Topics: Husbandry & ManagementAnimal Type: All/General

Citation: Dauchy, R. T. 2023. Vivarium lighting and the new measurement metrics. Laboratory Animal Science Professional 11(6) (November/December), 16-18.

Using a cost-effective, efficient method to train young dogs to cooperate for multiple blood collection procedures in a pharmacokinetics study

Behavioral testing slings, such as the Pavlov sling, offer an effective form of restraint for beagles while minimizing stress. Although these slings provide effective restraint, their high cost makes them less likely to be considered when discussing restraint options, especially...

Year Published: 2023Topics: Animal Training, Biological Sampling & Physiological Measurement, RestraintAnimal Type: Dog

Citation: Rexroat, E. K., Haughton, C. L., Fox, K. 2023. Using a cost-effective, efficient method to train young dogs to cooperate for multiple blood collection procedures in a pharmacokinetics study. Laboratory Animal Science Professional 11(6) (November/December), 34-36.

Increasing the psychological wellbeing of zebrafish (Danio rerio) and African clawed frogs (Xenopus laevis) at the Cleveland Clinic

With the increased use of aquatic animals in research, especially zebrafish and African clawed frogs, there has been an increased interest in how to best address their psychological wellbeing. In this article, we have shown various ways to improve the...

Year Published: 2023Topics: Environmental EnrichmentAnimal Type: Amphibian, Fish, Frog & Toad, Zebrafish

Citation: Wood, H., Voros, G. B. 2023. Increasing the psychological wellbeing of zebrafish (Danio rerio) and African clawed frogs (Xenopus laevis) at the Cleveland Clinic. Laboratory Animal Science Professional 11(6) (November/December), 38-40.

Enriching the lives of zebra finches

Zebra finches are an uncommon animal model in the biomedical industry but are widely used in language development, memory, and learning studies. Native to Australia, they are desert birds that like warm days and 40%+ relative humidity. As a social...

Year Published: 2024Topics: Environmental EnrichmentAnimal Type: Bird, Finch

Citation: Warner-Hough, M. 2024. Enriching the lives of zebra finches. Laboratory Animal Science Professional 12(1) (January/February), 28-30.

Overcoming the hurdles of lab animal enrichment: Natural behaviors vs. scientific need

The Animal Resources Core (ARC) at the Abigail Wexner Research Institute (AWRI) at Nationwide Children's Hospital (NCH) faces many of the same challenges other institutions manage in terms of enrichment for laboratory animals. A Behavior Assessment Team (BAT) was developed...

Year Published: 2024Topics: Environmental EnrichmentAnimal Type: Chinchilla, Fish, Goat, Mouse, Pig, Rabbit, Rat, Rodent, Sheep, Zebrafish

Citation: Mantz, M., Pugerud, A. 2024. Overcoming the hurdles of lab animal enrichment: Natural behaviors vs. scientific need. Laboratory Animal Science Professional 12(1) (January/February), 32-34.

How much wood could a woodchuck chuck if a woodchuck could chuck wood? Not much if they’re provided with the right enrichment!

Husbandry & Management,Environmental Enrichment

Year Published: 2024Topics: Environmental EnrichmentAnimal Type: Other Animal

Citation: Brennan, J. 2024. How much wood could a woodchuck chuck if a woodchuck could chuck wood? Not much if they're provided with the right enrichment! Laboratory Animal Science Professional 12(1) (January/February), 46-48.

A cost-effective restraint method for safer subcutaneous scruff injections and reducing stress in mice and handlers

Subcutaneous injection is a vital technique in mouse-based biomedical research. Compared to other injections, the subcutaneous method poses fewer technical challenges and reduces acute toxicity risks due to slower absorption. Several suitable subcutaneous injection sites exist in mice, including the...

Year Published: 2024Topics: Drug/Substance AdministrationAnimal Type: Mouse, Rodent

Citation: Fitzwater, A., Zhang, L. 2024. A cost-effective restraint method for safer subcutaneous scruff injections and reducing stress in mice and handlers. Laboratory Animal Science Professional 12(1) (January/February), 52-53.

How outing conditions relate to the motivation of movement-restricted cattle to access an outdoor exercise yard

Assessing animal motivation to access a given resource is one method available to evaluate what to provide in the living environments of captive animals. Providing increased opportunities for movement can be seen as an important source of enrichment, but we...

Year Published: 2023Topics: Environmental Enrichment, Husbandry & ManagementAnimal Type: Cattle

Citation: Aigueperse, N., Boyer, V., Vasseur, E. 2023. How outing conditions relate to the motivation of movement-restricted cattle to access an outdoor exercise yard. Behavioural Processes 213, 104957.

Thirty years of telemetry-based data acquisition for cardiovascular drug safety evaluation: Applications and optimization

Conducting safety evaluations of new drugs using conscious animals has been a specialty of our working group for thirty years. In this article, we review the various technical challenges and solutions dealt with over the years to improve both the...

Year Published: 2023Topics: Biological Sampling & Physiological Measurement, External Bodily EquipmentAnimal Type: Dog, Guinea Pig, Macaque, Mouse, Nonhuman Primate, Pig, Rat, Rodent

Citation: Alizadeh, E. A., Graf, K., Schiwon, J. et al. 2023. Thirty years of telemetry-based data acquisition for cardiovascular drug safety evaluation: Applications and optimization. Journal of Pharmacological and Toxicological Methods 122, 107279.

Comparison of subcutaneous sedation with alfaxalone or alfaxalone-midazolam in pet guinea pigs (Cavia porcellus) of three different age groups

OBJECTIVE To compare the cardiorespiratory effects, quality and duration of sedation of 2 subcutaneous sedation protocols for noninvasive procedures in guinea pigs (GPs). ANIMALS 24 pet GPs (15 females, 9 males) of 3 different age groups: infant (n = 8),...

Year Published: 2022Topics: Anesthesia & SedationAnimal Type: Guinea Pig, Rodent

Citation: Álvarez, E. R., Solé, L. V., Mateo, A. G. de C. 2022. Comparison of subcutaneous sedation with alfaxalone or alfaxalone-midazolam in pet guinea pigs (Cavia porcellus) of three different age groups. Journal of the American Veterinary Medical Association 260(9), 1024–1030.