Reproduction

Development of a 3D simulator for training the mouse in utero electroporation

In utero electroporation (IUE) requires high-level training in microinjection through the mouse uterine wall into the lateral ventricle of the mouse brain. Training for IUE is currently being performed in live mice as no artificial models allow simulations yet. This...

Year Published: 2022Topics: Disease/Experimental Model, Drug/Substance Administration, ReproductionAnimal Type: Mouse, Rodent

Citation: Nuber, M., Gonzalez-Uarquin, F., Neufurth, M. et al. 2022. Development of a 3D simulator for training the mouse in utero electroporation. PLOS ONE 17(12), e0279004.

Effects of castration and sterilization on baseline and response levels of cortisol—A case study in male guinea pigs

An uncontrolled reproduction of animals in human hands should be avoided. To meet this goal, animals are widely castrated, i.e., the gonads are completely removed. Since the gonads are the most important source of sex hormones, this is a serious...

Year Published: 2023Topics: Body Modification/Mutilation, ReproductionAnimal Type: All/General, Guinea Pig, Rodent

Citation: Kaiser, S., Korte, A., Wistuba, J. et al. 2023. Effects of castration and sterilization on baseline and response levels of cortisol—A case study in male guinea pigs. Frontiers in Veterinary Science 9, 1093157.

Does environmental colour matter to Zebrafish

The aim of this study was to determine if environmental colour affects the Zebrafrish (Danio rerio) performance metrics of survival, growth rates, fecundity, and fertility. This study created tanks of different colours (green, blue, and black) and included a clear...

Year Published: 2022Topics: Housing, Husbandry & Management, Rearing & Weaning, ReproductionAnimal Type: Fish, Zebrafish

Citation: Goldsmith, R., Wilson, C. 2022. Does environmental colour matter to Zebrafish. Animal Technology and Welfare 21(3), 234–237.

3R measures in facilities for the production of genetically modified rodents

Sociocultural changes in the human–animal relationship have led to increasing demands for animal welfare in biomedical research. The 3R concept is the basis for bringing this demand into practice: Replace animal experiments with alternatives where possible, Reduce the number of...

Year Published: 2022Topics: Analgesia, Disease/Experimental Model, Husbandry & Management, Reproduction, Surgery & Post-OpAnimal Type: Mouse, Rat, Rodent

Citation: Zevnik, B., Jerchow, B., Buch, T. 2022. 3R measures in facilities for the production of genetically modified rodents. Lab Animal 51(6), 162-177.

Confirming sexual maturity in male cynomolgus macaques by urinary spermatozoa microscopic examination

Medications often require studies performed in sexually mature cynomolgus macaques. At this time, there are few options available to confirm sexual maturity in male macaques. Electroejaculation and collection of seminal fluid are invasive and require either anesthesia or prolonged acclimation....

Year Published: 2022Topics: ReproductionAnimal Type: Macaque, Nonhuman Primate

Citation: Rosales, C., Sands, C. 2022. Confirming sexual maturity in male cynomolgus macaques by urinary spermatozoa microscopic examination. Laboratory Animal Science Professional 10(1) (January/February), 60-61.

Improving maternal welfare during gestation has positive outcomes on neonatal survival and modulates offspring immune response in pigs

Improving the housing of pregnant sows by giving them more space and access to deep straw had positive effects on their welfare, influenced their maternal behavior and improved the survival of their offspring. The present study aimed at determining whether...

Year Published: 2022Topics: Husbandry & Management, Rearing & Weaning, ReproductionAnimal Type: Pig

Citation: Merlot, E., Meunier-Salaün, M.-C., Peuteman, B. et al. 2022. Improving maternal welfare during gestation has positive outcomes on neonatal survival and modulates offspring immune response in pigs. Physiology & Behavior 249, 113751.

Magnetic resonance imaging for early pregnancy diagnosis in the laboratory rat

Pregnancy diagnosis and embryo counting are important end points in reproductive, developmental biology and toxicology studies. The purpose of the present study was to assess the feasibility and efficacy of magnetic resonance imaging (MRI) for early pregnancy diagnosis and embryo...

Year Published: 2021Topics: ReproductionAnimal Type: Rat, Rodent

Citation: Ypsilantis, P., Souftas, V., Vyza, V. et al. 2021. Magnetic resonance imaging for early pregnancy diagnosis in the laboratory rat. Laboratory Animals 55(3), 262-269.

Retrospective analysis of the effectiveness and reversibility of long-acting contraception Etonogestrel (Implanon®) in common marmosets (Callithrix jacchus)

Contraception is an important population control method for the colony management of primates housed in captivity. Etonogestrel (ENG) implants (i.e., Implanon®) are a widely used progestin-based contraceptive in common marmosets (Callithrix jacchus) with the theoretical advantages of being reversible and...

Year Published: 2021Topics: ReproductionAnimal Type: Marmoset, Nonhuman Primate

Citation: Roubos, S., Louwerse, A. L., Langermans, J. A. M. et al. 2021. Retrospective analysis of the effectiveness and reversibility of long-acting contraception Etonogestrel (Implanon®) in common marmosets (Callithrix jacchus). Animals 11(4), 963.

Replacement of surgical vasectomy through the use of wild-type sterile hybrids

For the production and rederivation of mouse strains, pseudopregnant female mice are used for embryo transfer and serve as surrogate mothers to support embryo development to term. Vasectomized males are commonly used to render pseudopregnancy in females, generated by surgical...

Year Published: 2021Topics: ReproductionAnimal Type: Mouse, Rodent

Citation: Preece, C., Alghadban, S., Bouchareb, A. et al. 2021. Replacement of surgical vasectomy through the use of wild-type sterile hybrids. Lab Animal 50, 49-52.

Improved timed-mating, non-invasive method using fewer unproven female rats with pregnancy validation via early body mass increases

For studies requiring accurate conception-timing, reliable, efficient methods of detecting oestrus reduce time and costs, whilst improving welfare. Standard methods use vaginal cytology to stage cycle, and breeders are paired-up using approximately five proven females with proven males to achieve...

Year Published: 2019Topics: ReproductionAnimal Type: Rat, Rodent

Citation: Stramek, A. K., Johnson, M. L., Taylor, V. J. 2019. Improved timed-mating, non-invasive method using fewer unproven female rats with pregnancy validation via early body mass increases. Laboratory Animals 53(2), 148–159.