Euthanasia

Wellbeing of mice euthanized with carbon dioxide in their home cage as compared with an induction chamber

The AVMA Guidelines on Euthanasia state that, to decrease potential distress of animals, the home cage should be used for the euthanasia of mice. The current study evaluated this recommendation by comparing behavioral and physiologic changes in ICR and SJL...

Year Published: 2021Topics: EuthanasiaAnimal Type: Mouse, Rodent

Citation: Hickman, D. L. 2021. Wellbeing of mice euthanized with carbon dioxide in their home cage as compared with an induction chamber. JAALAS 60(1), 72-76.

International survey on the use and welfare of zebrafish Danio rerio in research

A survey was conducted regarding zebrafish Danio rerio use for scientific research with a focus on: anaesthesia and euthanasia; housing and husbandry; breeding and production; refinement opportunities. A total of 98 survey responses were received from laboratories in 22 countries...

Year Published: 2017Topics: Anesthesia & Sedation, Environmental Enrichment, Euthanasia, Housing, Husbandry & Management, Identification Method, ReproductionAnimal Type: Fish, Zebrafish

Citation: Lidster, K., Readman, G. D., Prescott, M. J. et al. 2017. International survey on the use and welfare of zebrafish Danio rerio in research. Journal of Fish Biology 90(5), 1891-1905.

Cephalopod biology and care, a COST FA1301 (CephsInAction) training school: Anaesthesia and scientific procedures

Cephalopods are the sole invertebrates included in the list of regulated species following the Directive 2010/63/EU. According to the Directive, achieving competence through adequate training is a requisite for people having a role in the different functions (article 23) as...

Year Published: 2017Topics: Anesthesia & Sedation, Euthanasia, Natural Behavior, Relocation & TransportAnimal Type: Cephalopod, Invertebrate

Citation: Lopes, V. M., Sampaio, E., Roumbedakis, K. et al. 2017. Cephalopod biology and care, a COST FA1301 (CephsInAction) training school: Anaesthesia and scientific procedures. Invertebrate Neuroscience 17, 8.

Assessment of pain associated with the injection of sodium pentobarbital in laboratory mice (Mus musculus)

The AVMA Guidelines for the Euthanasia of Animals considers injection of barbiturates to be an acceptable method of euthanasia in rodents but states there is a potential for pain when administered intraperitoneally. This study examined the potential for pain in...

Year Published: 2019Topics: Drug/Substance Administration, EuthanasiaAnimal Type: Mouse, Rodent

Citation: Dutton III, J. W., Artwohl, J. E., Huang, X. et al. 2019. Assessment of pain associated with the injection of sodium pentobarbital in laboratory mice (Mus musculus). JAALAS 58(3), 373-379.

The role of emotional contagion in the distress exhibited by grouped mice exposed to CO2

The 2013 AVMA Guidelines for the Euthanasia of Animals recommends a chamber volume displacement rate of 10% to 30% per minute (v/min) when euthanizing small laboratory rodents with CO2. Group euthanasia of mice is a common practice, and grouping strangers...

Year Published: 2019Topics: EuthanasiaAnimal Type: Mouse, Rodent

Citation: Moffitt, A. D., Brignolo, L. L., Ardeshir, A. et al. 2019. The role of emotional contagion in the distress exhibited by grouped mice exposed to CO2. JAALAS 58(4), 430-437.

Disaster planning for animals in hazardous agent containment units

Disaster response planning for laboratory animal facilities is a time- and personnel-intensive undertaking. This article outlines numerous considerations in formulating a plan for disaster response in a high containment animal unit. The planning process is discussed around a set of...

Year Published: 2018Topics: EuthanasiaAnimal Type: All/General

Citation: Roble, G., Pullium, J., Hester, T. et al. 2018. Disaster planning for animals in hazardous agent containment units. ILAR Journal 59(2), 195–202.

Anesthesia and euthanasia of brine shrimp (Artemia franciscana)

Invertebrates are often overlooked as laboratory animals, yet they are commonly used in toxicology, developmental, cellular and molecular biology, and radiation studies with euthanasia as an endpoint. Little is known regarding appropriate euthanasia methods for invertebrate species, particularly for Artemia....

Year Published: 2019Topics: Anesthesia & Sedation, EuthanasiaAnimal Type: Crustacean, Invertebrate

Citation: Darbyshire, A. K., Oliver, K. H., Dupont, W. D. et al. 2019. Anesthesia and euthanasia of brine shrimp (Artemia franciscana). JAALAS 58(1), 58-63.

Humanely ending the life of animals: Research priorities to identify alternatives to carbon dioxide

The use of carbon dioxide (CO2) for stunning and killing animals is considered to compromise welfare due to air hunger, anxiety, fear, and pain. Despite decades of research, no alternatives have so far been found that provide a safe and...

Year Published: 2019Topics: EuthanasiaAnimal Type: Bird, Chicken, Mouse, Pig, Rat

Citation: Steiner, A. R., Axiak Flammer, S., Beausoleil, N. J. et al. 2019. Humanely ending the life of animals: Research priorities to identify alternatives to carbon dioxide. Animals 9(11), 911.

Physiological and behavioral indicators to measure crustacean welfare

The purpose of this project was to determine how neural circuits were affected during warming by examining sensory neurons, the neuromuscular junction, and the cardiac function and behavior of the commercially important crustacean species, the red swamp crayfish (Procambarus clarkii)....

Year Published: 2019Topics: EuthanasiaAnimal Type: Crustacean, Invertebrate

Citation: Adams, R., Stanley, C. E., Piana, E. et al. 2019. Physiological and behavioral indicators to measure crustacean welfare. Animals 9(11), 914.

Efficacy of a novel mechanical cervical dislocation device in comparison to manual cervical dislocation in layer chickens

The main objective of this study was to assess the efficacy of mechanical cervical dislocation using the Koechner Euthanasia Device Model C (KED) in comparison to manual cervical dislocation in layer chickens. Laying hens and/or roosters in three different age...

Year Published: 2019Topics: EuthanasiaAnimal Type: Bird, Chicken

Citation: Bandara, R. M.A.S., Torrey, S., Turner, P. V. et al. 2019. Efficacy of a novel mechanical cervical dislocation device in comparison to manual cervical dislocation in layer chickens. Animals 9(7), 407.