Publications
Enriched environment effect on lipopolysaccharide-induced spatial learning, memory impairment and hippocampal inflammatory cytokine levels in male rats
Neuro-inflammation is responsible for cognitive impairments and neurodegenerative diseases such as Alzheimer’s disease. In this study, we aimed to investigate the enriched environment (EE) effect on learning and memory impairment as well as on pro-inflammatory cytokines changes induced by lipopolysaccharide...
Year Published: 2020Topics: Environmental EnrichmentAnimal Type: Rat, Rodent
Citation: Keymoradzadeh, A., Hedayati Ch, M., Abedinzade, M. et al. 2020. Enriched environment effect on lipopolysaccharide-induced spatial learning, memory impairment and hippocampal inflammatory cytokine levels in male rats. Behavioural Brain Research 394, 112814.
Read MoreEnriched environments enhance cognition, exploratory behaviour and brain physiological functions of Sparus aurata
Environmental enrichment is considered as a recommended tool to guarantee or improve the welfare of captive fish. This study demonstrates for the first time that structural environmental enrichment enhances cognition, exploratory behaviour and brain physiological functions of gilthead seabream (Sparus...
Year Published: 2020Topics: Environmental EnrichmentAnimal Type: Fish, Other Fish
Citation: Arechavala-Lopez, P., Caballero-Froilán, J. C., Jiménez-García, M. et al. 2020. Enriched environments enhance cognition, exploratory behaviour and brain physiological functions of Sparus aurata. Scientific Reports 10, 11252.
Read MoreEnrichment preferences of singly housed zebrafish (Danio rerio)
Despite the increasing popularity of zebrafish (Danio rerio) as an animal model, the environmental enrichment preferences of this species have been largely unexplored. We sought to determine the preferences of mature female zebrafish that were singly housed with or without...
Year Published: 2020Topics: Environmental EnrichmentAnimal Type: Fish, Zebrafish
Citation: Krueger, L. D., Thurston, S. E., Kirk, J. et al. 2020. Enrichment preferences of singly housed zebrafish (Danio rerio). JAALAS 59(2), 148–155.
Read MoreEvaluating intrahepatic and intraperitoneal sodium pentobarbital or ethanol for mouse euthanasia
Intraperitoneal (IP) injection of sodium pentobarbital (PB) is an accepted method of euthanasia for mice. However, this method has important drawbacks, including the potential for pain or misinjection. The objective of this prospective, randomized, blinded study was to determine whether...
Year Published: 2020Topics: EuthanasiaAnimal Type: Mouse, Rodent
Citation: Laferriere, C. A., Leung, V. S., Pang, D. S. 2020. Evaluating intrahepatic and intraperitoneal sodium pentobarbital or ethanol for mouse euthanasia. JAALAS 59(3), 264–268.
Read MoreEvaluation of an acute osmotic stress in European sea bass via skin mucus biomarkers
European sea bass is a marine teleost which can inhabit a broad range of environmental salinities. So far, no research has studied the physiological response of this fish to salinity challenges using modifications in skin mucus as a potential biological...
Year Published: 2020Topics: Biological Sampling & Physiological Measurement, Husbandry & Management, Welfare AssessmentAnimal Type: Fish, Other Fish
Citation: Ordóñez-Grande, B., Guerreiro, P. M., Sanahuja, I. et al. 2020. Evaluation of an acute osmotic stress in European sea bass via skin mucus biomarkers. Animals 10(9), 1546.
Read MoreEvaluation of cotton dental rolls as environmental enrichment for mice
Historically, we provided 2 compressed cotton squares for nesting and enrichment. The logistics of managing nesting material distribution, disposal, and costs are major considerations for our program, which provides husbandry to approximately 60,000 rodent cages weekly. We identified cotton dental...
Year Published: 2020Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent
Citation: Rodgers, J. C., Ricart Arbona, R. J., Lieggi, C. et al. 2020. Evaluation of cotton dental rolls as environmental enrichment for mice. Laboratory Animal Science Professional 8(5) (September/October), 70-71.
Read MoreEvaluation of effective and practical euthanasia methods for larval African clawed frogs (Xenopus laevis)
Larval, or tadpole-stage Xenopus laevis frogs are a popular research model for developmental biology and disease studies. Existing euthanasia guidance documents offer recommendations for both eggs and adult stages, yet do not specifically address the larval stage. Data evaluating effective...
Year Published: 2020Topics: EuthanasiaAnimal Type: Amphibian, Frog & Toad
Citation: Galex, I. A., Gallant, C. M., D'Avignon, N. et al. 2020. Evaluation of effective and practical euthanasia methods for larval African clawed frogs (Xenopus laevis). JAALAS 59(3), 269–274.
Read MoreEvaluation of infrared thermography as a non-invasive method of measuring the autonomic nervous response in sheep
Eye temperature measured using infrared thermography (IRT) can be used as a non-invasive measure of autonomic nervous system (ANS) activity in cattle. The objective of this study was to evaluate if changes in eye temperature (measured using IRT) can be...
Year Published: 2020Topics: Biological Sampling & Physiological Measurement, Welfare AssessmentAnimal Type: Sheep
Citation: Sutherland, M. A., Worth, G. M., Dowling, S. K. et al. 2020. Evaluation of infrared thermography as a non-invasive method of measuring the autonomic nervous response in sheep. PLOS ONE 15(5): e0233558.
Read MoreEvaluation of subcutaneous administration of alfaxalone-midazolam and dexmedetomidine-midazolam for sedation of ball pythons (Python regius)
OBJECTIVE: To evaluate SC administration of alfaxalone-midazolam and dexmedetomidine-midazolam for sedation of ball pythons (Python regius). ANIMALS: 12 healthy juvenile ball pythons. PROCEDURES: In a randomized crossover study, each snake was administered a combination of alfaxalone (5 mg/kg [2.3 mg/lb])...
Year Published: 2020Topics: Anesthesia & SedationAnimal Type: Reptile, Snake
Citation: Yaw, T. J., Mans, C., Johnson,S. et al. 2020. Evaluation of subcutaneous administration of alfaxalone-midazolam and dexmedetomidine-midazolam for sedation of ball pythons (Python regius). Journal of the American Veterinary Medical Association 256(5), 573-579.
Read MoreEvaluation of subcutaneous administration of alfaxalone-midazolam and ketamine-midazolam as sedation protocols in African pygmy hedgehogs (Atelerix albiventris)
OBJECTIVE: To evaluate SC administration of 2 sedation protocols, ketamine-midazolam (KM) and alfaxalone-midazolam (AM), in African pygmy hedgehogs (Atelerix albiventris). ANIMALS: 9 healthy adult hedgehogs (5 males, 4 females). PROCEDURES: A randomized, blinded, complete crossover study was performed. Sedation was...
Year Published: 2020Topics: Anesthesia & SedationAnimal Type: Other Animal
Citation: Hawkins, S. J., Doss, G. A., Mans, C. 2020. Evaluation of subcutaneous administration of alfaxalone-midazolam and ketamine-midazolam as sedation protocols in African pygmy hedgehogs (Atelerix albiventris). Journal of the American Veterinary Medical Association 257(8), 820-825.
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