Publications

Recovery of horses from general anesthesia after induction with propofol and ketamine versus midazolam and ketamine

OBJECTIVE To evaluate quality of recovery from general anesthesia in horses after induction with propofol and ketamine versus midazolam and ketamine. DESIGN Prospective randomized crossover study. ANIMALS 6 healthy adult horses. PROCEDURES Horses were premedicated with xylazine (1.0 mg/kg [0.45...

Year Published: 2018Topics: Anesthesia & SedationAnimal Type: Equine

Citation: Jarrett, M. A., Bailey, K. M., Messenger, K. M. et al. 2018. Recovery of horses from general anesthesia after induction with propofol and ketamine versus midazolam and ketamine. Journal of the American Veterinary Medical Association 253(1), 101-107.

Use of tricaine methanesulfonate or propofol for immersion euthanasia of goldfish (Carassius auratus)

OBJECTIVE To substantiate current AVMA guidelines for immersion euthanasia of goldfish (Carassius auratus) with tricaine methanesulfonate (TMS), determine whether immersion in propofol at 5 times its immersion anesthesia concentration for 30 minutes is sufficient for euthanasia of goldfish, and quantify...

Year Published: 2018Topics: EuthanasiaAnimal Type: Fish, Other Fish

Citation: Balko, J. A., Oda, A., Posner, L. P. 2018. Use of tricaine methanesulfonate or propofol for immersion euthanasia of goldfish (Carassius auratus). Journal of the American Veterinary Medical Association 252(12), 1555-1561.

Effects of alfaxalone administered intravenously to healthy yearling loggerhead sea turtles (Caretta caretta) at three different doses

OBJECTIVE To compare physiologic and anesthetic effects of alfaxalone administered IV to yearling loggerhead sea turtles (Caretta caretta) at 3 different doses. DESIGN Randomized crossover study. ANIMALS 9 healthy yearling loggerhead sea turtles. PROCEDURES Animals received each of 3 doses...

Year Published: 2017Topics: Anesthesia & SedationAnimal Type: Reptile, Turtle & Tortoise

Citation: Phillips, B. E., Posner, L. P., Lewbart, G. A. et al. 2017. Effects of alfaxalone administered intravenously to healthy yearling loggerhead sea turtles (Caretta caretta) at three different doses. Journal of the American Veterinary Medical Association 250(8), 909-917.

Report of the 2017 RSPCA/UFAW Rodent and Rabbit Welfare Group meeting

The RSPCA/UFAW Rodent (and now Rabbit) Welfare Group held a one-day meeting on 14 November 2017 in Weybridge, UK. The first session addressed meeting animals' needs and aiming for a 'good life', with the needs of female breeding rabbits as...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Mouse, Rodent

Citation: Hawkins, P., McBride, A., Paiba, G. et al. 2018. Report of the 2017 RSPCA/UFAW Rodent and Rabbit Welfare Group meeting. Animal Technology and Welfare 17(2), 75-83. [Meeting Report]

Refinement of tumour passage by optimisation of the tissue disaggregation protocol

Surgical implantation of tumour pieces has been used regularly in the passage of tumour models. This involves an invasive surgical procedure, carried out under anaesthesia, ensuring mice have adequate pain relief and peri-operative care. The procedure also requires multiple tumour-bearing...

Year Published: 2018Topics: Drug/Substance AdministrationAnimal Type: Mouse, Rodent

Citation: Galvin, M., Lallo, A., Brown, S. et al. 2018. Refinement of tumour passage by optimisation of the tissue disaggregation protocol. Animal Technology and Welfare 17(2), 101-103.

Blunting/cutting canines of adult male monkeys: A discussion by the Laboratory Animal Refinement & Enrichment Forum

"When you keep adult Rhesus macaque (Macaca mulatta) males, adult Cynomolgus (Macaca fascicularis) males or adult Vervet males (Chlorocebus pygerythrus), in the same enclosure, is it advisable to have the canines of the males blunted or cut?" - question posed...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Coke, C., Skoumbourdis, E., Rodgers, J. C. et al. 2018. Blunting/cutting canines of adult male monkeys: A discussion by the Laboratory Animal Refinement & Enrichment Forum. Animal Technology & Welfare 17(2), 105-107.

A refinement to Schedule 1

There are varying methods used for animal restraint and angle of injection. It remains unclear whether one method is more accurate than others. The primary objectives were to examine whether inverted restraint of rats resulted in more effective outcomes and...

Year Published: 2018Topics: Drug/Substance AdministrationAnimal Type: Rat, Rodent

Citation: Read, H., Perry, R. 2018. A refinement to Schedule 1. Animal Technology and Welfare 17(2), 117-120.

Improving rabbit enrichment: Developing a rolling enrichment plan

A three-week enrichment preference study trialling different substrates, food and pen structures was carried out in three, group-housed female New Zealand White Rabbits (NZW). Preference results: structural - rabbits spent the most time with a circular table (repurposed empty wooden...

Year Published: 2018Topics: Environmental Enrichment, HousingAnimal Type: Rabbit

Citation: Pearson, K., Gant, J. 2018. Improving rabbit enrichment: Developing a rolling enrichment plan. Animal Technology and Welfare 17(2), 121-123.

Design by intravenous injection in the Syrian hamster

Repeated injections in rats and mice are typically done via the tail vein. For hamsters, the tail is not an option. In this paper we explore the development and refinement of IV dosing in the Syrian hamster via the jugular...

Year Published: 2018Topics: Drug/Substance AdministrationAnimal Type: Hamster, Rodent

Citation: Beamish, G., Chapman, C., Lomax, A. 2018. Design by intravenous injection in the Syrian hamster. Animal Technology and Welfare 17(2), 124-125.

Refinements to animal husbandry for continuous infusion dosing in Beagle dogs

At Envigo we are contracted by our customers to conduct studies, usually to evaluate the safety of new drugs and chemicals. A rodent and non-rodent species are usually involved in this testing with the method of administration designed to replicate...

Year Published: 2018Topics: External Bodily EquipmentAnimal Type: Dog

Citation: Allen, L. 2018. Refinements to animal husbandry for continuous infusion dosing in Beagle dogs. Animal Technology and Welfare 17(2), 126-127.