Publications

Ultrasound to UltraSee: The use of ultrasound to determine pregnancy in mice

In March 2017 MRC Ares bought an ultrasound machine to assist in determining pregnancy in timed mating mice. Prior to this, visual checks or palpation would be used to confirm pregnancy. There were limitations with these methods as mice generally...

Year Published: 2019Topics: ReproductionAnimal Type: Mouse, Rodent

Citation: Kemp, K. 2018. Ultrasound to UltraSee: The use of ultrasound to determine pregnancy in mice. Animal Technology and Welfare 17(3), 193-195 (IAT Congress 2018 Poster Presentation).

Three little pigs! straw, sticks and bricks: ‘I’ll blow your house down’

In order for a scientific project involving animals to run smoothly, it is essential that the Animal Technologists have a good understanding of both the animals they are dealing with and of the project itself. Therefore our input to the...

Year Published: 2019Topics: Environmental Enrichment, HousingAnimal Type: Pig

Citation: Duckett, L., Phelon, L., Wheeler, L. 2018.Three little pigs! straw, sticks and bricks: ‘I'll blow your house down'. Animal Technology and Welfare 17(3), 201-203 (IAT Congress 2018 Poster Presentation).

I3S software as a refinement technique to identify individuals within a captive Scyliorhinus canula population

Demarking individual animals within a group is often required in research. However, the process of invasive tagging induces stress and if a tag becomes detached it may wound the animal and/or prevent identification. Photo identification using natural marks can be...

Year Published: 2019Topics: Identification MethodAnimal Type: Amphibian, Fish, Frog & Toad, Other Fish, Zebrafish

Citation: McMurray, C., Allen, N., Hook, S. et al. 2018. I3S software as a refinement technique to identify individuals within a captive Scyliorhinus canula population. Animal Technology and Welfare 17(3), 204-205 (IAT Congress 2018 Poster Presentation).

Give us a break!

Literature is replete with studies on stressors to laboratory rodents; knowing the impact research and husbandry interventions, such as routine cage changing, have on rodents' stress levels, physiology and behaviour, we hypothesised that animals recovering in a familiar environment would...

Year Published: 2019Topics: Disease/Experimental Model, Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Filby, E. 2019. Give us a break! Animal Technology and Welfare 18(1), 45-48.

Using novel equipment to aid reduction and replacement of the ferret model in influenza transmission

The ferret model has long been the “gold standard” animal model for studying human influenza infection and is used all around the world for transmission studies. Professor Wendy Barclay and her team have used ferrets at Imperial College for 10...

Year Published: 2019Topics: Disease/Experimental ModelAnimal Type: Ferret

Citation: Boreham, T. 2019. Using novel equipment to aid reduction and replacement of the ferret model in influenza transmission. Animal Technology and Welfare 18(1), 59-61.

Optimising health & welfare tracking using the Sanger Mouse Database

Health tracking of animals is required legally under the Animals (Scientific Procedures) Act 1986 (ASPA) to prevent pain, avoidable suffering, distress or lasting harm. This is important with Genetically Modified (GM) animals as they are more likely to have unexpected...

Year Published: 2019Topics: Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Dench, J., McLaren-Jones, R., Vancollie, V. et al. 2019. Optimising health & welfare tracking using the Sanger Mouse Database. Animal Technology and Welfare 18(1), 62-64.

Refining mouse re-derivation by using in vitro fertilisation (IVF) with fresh or frozen sperm as opposed to embryos

To attempt to reduce, refine and replace, we have employed a several new approaches to rederive mouse strains. By using in vitro fertilisation (IVF) with fresh or frozen sperm we can reduce the timeframe and number of animals required to...

Year Published: 2019Topics: ReproductionAnimal Type: Mouse, Rodent

Citation: Travers, A., Thomson, J., Sharp, M. 2019. Refining mouse re-derivation by using in vitro fertilisation (IVF) with fresh or frozen sperm as opposed to embryos. Animal Technology and Welfare 18(1), 73-74.

Using subcuticular stitching in rats to replace skin closure clips as a refinement

Skin closure clips are widely used within the University of Edinburgh to close incision sites for various procedures in both rats and mice. In rats the skin closure clips very often come out as a result of cage mates biting...

Year Published: 2019Topics: Surgery & Post-OpAnimal Type: Rat, Rodent

Citation: Thomson, J., Mungall, W. 2019. Using subcuticular stitching in rats to replace skin closure clips as a refinement. Animal Technology and Welfare 18(1), 75-76.

Report of the 2018 RSPCA/UFAW Rodent and Rabbit Welfare Group meeting

The RSPCA/UFAW Rodent (and now Rabbit) Working Group has held a one-day meeting every autumn for the last 25 years, so that its members can discuss current welfare research, exchange views on welfare issues and share experiences of the implementation...

Year Published: 2019Topics: Anesthesia & Sedation, Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Stevens, C., Hawkins, P., Lovell-Badge, R. et al. 2019. Report of the 2018 RSPCA/UFAW Rodent and Rabbit Welfare Group meeting. Animal Technology and Welfare 18(2), 81-91.

A comparison of enrichment items for the promotion of natural gnawing behaviour in laboratory mice

Appropriate housing and husbandry, including environmental enrichment, must take the natural habitat, biology and behaviour of each species into consideration. The Guide for the Care and Use of Laboratory Animals (1996) states that the goal should always be to maximise...

Year Published: 2019Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Lopez Juaristi, 2019. A comparison of enrichment items for the promotion of natural gnawing behaviour in laboratory mice. Animal Technology and Welfare 18(2), 93-97.