Publications

Caloric restriction in group-housed mice: Littermate and sex influence on behavioral and hormonal data

Much of the research done on aging, oxidative stress, anxiety, and cognitive and social behavior in rodents has focused on caloric restriction (CR). This often involves several days of single housing, which can cause numerous logistical problems, as well as...

Year Published: 2021Topics: Disease/Experimental Model, Husbandry & Management, Social Housing & CompanionshipAnimal Type: Mouse, Rodent

Citation: Perea, C., Vázquez-Ágredos, A., Ruiz-Leyva, L. et al. 2021. Caloric restriction in group-housed mice: Littermate and sex influence on behavioral and hormonal data. Frontiers in Veterinary Science 8, 639187.

Behavioral management is a key component of ethical research

Behavioral management programs aim to enhance the welfare of animal subjects that participate in research, thereby enhancing our ability to conduct ethical research projects. Socialization strategies, environmental enrichment techniques, opportunities for subjects to voluntarily participate in research procedures, and the...

Year Published: 2019Topics: Environmental Enrichment, Social Housing & CompanionshipAnimal Type: All/General

Citation: Schapiro, S. J., Neal Webb, S. J., Mulholland, M. M. et al. 2019. Behavioral management is a key component of ethical research. ILAR Journal 60(3), 389-396.

Moving beyond the absence of pain and distress: Focusing on positive animal welfare

For many years, researchers, veterinarians, animal ethics committees, and regulators have focused on minimizing pain and distress as a primary goal of refinement when working with animals in science. More recent publications as well as a shift in animal ethics...

Year Published: 2019Topics: Welfare AssessmentAnimal Type: All/General

Citation: Turner, P. V. 2019. Moving beyond the absence of pain and distress: Focusing on positive animal welfare. ILAR Journal 60(3), 366-372.

A good life for laboratory rodents?

Most would agree that animals in research should be spared “unnecessary” harm, pain, or distress, and there is also growing interest in providing animals with some form of environmental enrichment. But is this the standard of care that we should...

Year Published: 2019Topics: Environmental Enrichment, Handling, Housing, Husbandry & Management, Natural Behavior, RestraintAnimal Type: Mouse, Rat, Rodent

Citation: Makowska, I. J., Weary, D. M. 2019. A good life for laboratory rodents? ILAR Journal 60(3), 373-388.

Mouse anesthesia: The art and science

There is an art and science to performing mouse anesthesia, which is a significant component to animal research. Frequently, anesthesia is one vital step of many over the course of a research project spanning weeks, months, or beyond. It is...

Year Published: 2021Topics: Anesthesia & SedationAnimal Type: Mouse, Rodent

Citation: Navarro, K. L., Huss, M., Smith, J. C. et al. 2021. Mouse anesthesia: The art and science. ILAR Journal 62(1-2), 238-273.

Practical euthanasia method for common sea stars (Asterias rubens) that allows for high-quality RNA sampling

Sea stars in research are often lethally sampled without available methodology to render them insensible prior to sampling due to concerns over sufficient sample quality for applied molecular techniques. The objectives of this study were to describe an inexpensive and...

Year Published: 2021Topics: EuthanasiaAnimal Type: Invertebrate, Other Invertebrate

Citation: Wahltinez, S. J., Kroll, K. J., Nunamaker, E. A. et al. 2021. Practical euthanasia method for common sea stars (Asterias rubens) that allows for high-quality RNA sampling. Animals 11(7), 1847.

Influence of female coalitionary aggressive behavior on the success of male introductions to female groups of rhesus macaques (Macaca Mulatta)

Migration patterns of wild rhesus macaque males are often mimicked in captivity by introducing unfamiliar males to female groups every few years. This strategy prevents inbreeding and has been shown to encourage group stability once males are fully integrated. The...

Year Published: 2021Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Bailey, K. L., Bloomsmith, M. A., Michopoulos, V. et al. 2021. Influence of female coalitionary aggressive behavior on the success of male introductions to female groups of rhesus macaques (Macaca Mulatta). Applied Animal Behaviour Science 237, 105293.

Environmental enrichment impacts discrimination between familiar and unfamiliar human odours in snakes (Pantherophis guttata)

Environmental enrichment has been found to significantly influence the cognitive abilities of a variety of mammalian and avian species, with effects ranging from positive to negative, however, these effects have been little studied in reptiles. This is problematic given their...

Year Published: 2021Topics: Environmental EnrichmentAnimal Type: Reptile, Snake

Citation: Nagabaskaran, G., Burman, O. H. P., Hoehfurtner, T. et al. 2021. Environmental enrichment impacts discrimination between familiar and unfamiliar human odours in snakes (Pantherophis guttata). Applied Animal Behaviour Science 237, 105278.

Does the provision of environmental enrichment affect the behaviour and welfare of captive snakes?

There is a wealth of evidence demonstrating the benefits of environmental enrichment across a range of different animal species. However, there is comparatively little such research into the effect of enrichment provision on captive reptiles. The aim of this study...

Year Published: 2021Topics: Environmental EnrichmentAnimal Type: Reptile, Snake

Citation: Hoehfurtner, T., Wilkinson, A., Nagabaskaran, G. et al. 2021. Does the provision of environmental enrichment affect the behaviour and welfare of captive snakes? Applied Animal Behaviour Science 239, 105324.

Training pigs for oral glucose tolerance test—Six years’ experience of a refined model

Animal models of human diseases are important in biomedical research. When using animals for scientific purposes, the 3Rs (replace, reduce, refine) should be considered. Refinement of animal models is essential to ensure best use of animals, which is important for...

Year Published: 2021Topics: Animal Training, Drug/Substance AdministrationAnimal Type: Pig

Citation: Manell, E., Hedenqvist, P., Jensen-Waern, M. 2021. Training pigs for oral glucose tolerance test—Six years' experience of a refined model. Animals 11(6), 1677.