Publications

Husbandry techniques for a research colony of veiled chameleons (Chamaeleo calyptratus)

Although most chameleon species can be challenging captives, C. calyptratus have been successfully kept and bred in captivity for over thirty years. Despite their relative familiarity, our challenge is to replicate their preferred habitats in a practical way while also...

Year Published: 2021Topics: Housing, Husbandry & ManagementAnimal Type: Lizard, Reptile

Citation: Jewell, D., Muensch, A., Kupronis, R. et al. 2021. Husbandry techniques for a research colony of veiled chameleons (Chamaeleo calyptratus). Laboratory Animal Science Professional 9(4) (July/August), 52-55.

Effect of chronic handling and social isolation on emotion and cognition in adolescent rats

Adolescence is a critical period of establishing social relations through social interactions that affect the emotional development associated with stress responses, anxiety, depression, and cognitive development. We investigated the behavioral and neurobiological changes induced by handling and social isolation in...

Year Published: 2021Topics: Emotion, Pain, & Sentience, HandlingAnimal Type: Rat, Rodent

Citation: Song, M. K., Lee, J. H., Kim, Y.-J. 2021. Effect of chronic handling and social isolation on emotion and cognition in adolescent rats. Physiology & Behavior 237, 113440.

Animal-appropriate housing of ball pythons (Python regius)—Behavior-based evaluation of two types of housing systems

Considering animal welfare, animals should be kept in animal-appropriate and stress-free housing conditions in all circumstances. To assure such conditions, not only basic needs must be met, but also possibilities must be provided that allow animals in captive care to...

Year Published: 2021Topics: Environmental Enrichment, HousingAnimal Type: Reptile, Snake

Citation: Hollandt, T., Baur, M., Wöhr, A.-C. 2021. Animal-appropriate housing of ball pythons (Python regius)—Behavior-based evaluation of two types of housing systems. PLOS ONE 16(5), e0247082.

Proof of concept: Visual categorization of carotenoid pigmentation in Arctic charr (Salvelinus alpinus L) can predict stress response

Carotenoid pigmentation in Salvelinus alpinus has been connected to stress responsiveness in earlier studies. This has, however, only been tested with time-consuming image analysis from photos. Here, we used quick visual categorization of carotenoid pigmentation to investigate the stress responsiveness...

Year Published: 2021Topics: Welfare AssessmentAnimal Type: Fish, Other Fish

Citation: Backström, T., Brännäs, E., Nilsson, J. et al. 2021. Proof of concept: Visual categorization of carotenoid pigmentation in Arctic charr (Salvelinus alpinus L) can predict stress response. Journal of Fish Biology 98(4), 1192-1195.

Comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-detomidine-butorphanol, tiletamine-zolazepam-xylazine-butorphanol, and ketamine-detomidine-butorphanol in pigs

OBJECTIVE: To evaluate and compare the anesthetic, analgesic, and cardiorespiratory effects of tiletamine-zolazepam-detomidine-butorphanol (TZDB), tiletamine-zolazepam-xylazine-butorphanol (TZXB), and ketamine-detomidine-butorphanol (KDB) in pigs and to assess anesthetic recovery duration and quality following administration of tolazoline as a reversal agent. ANIMALS: 11 healthy...

Year Published: 2021Topics: Anesthesia & SedationAnimal Type: Pig

Citation: Chang, L.-J., Ko, J. C., Weil, A. B. et al. 2021. Comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-detomidine-butorphanol, tiletamine-zolazepam-xylazine-butorphanol, and ketamine-detomidine-butorphanol in pigs. Journal of the American Veterinary Medical Association 258(8), 883-891.

Assessing choice ability and preferences of five Leopard Tortoises (Stigmochelys pardalis) for three stimuli through a novel two-phase preference test

Preference testing has long been used in ethology and animal welfare science to assess the preferences that animals have for different resources and stimuli. The study conducted herein assessed the choice-making ability of five leopard tortoises Stigmochelys pardalis in a...

Year Published: 2021Topics: Human-Animal InteractionAnimal Type: Reptile, Turtle & Tortoise

Citation: Learmonth, M. J., Sherwen, S., Hemsworth, P. 2021. Assessing choice ability and preferences of five Leopard Tortoises (Stigmochelys pardalis) for three stimuli through a novel two-phase preference test. Journal of Zoo and Aquarium Research, 9(2), 94-101.

Using individual-specific conditioning to reduce stereotypic behaviours: A study on smooth dogfish Mustelus canis in captivity

Despite how frequently stereotypic behaviours are discussed in the field of animal behaviour and welfare, research on stereotypies in captive elasmobranchs is far less represented in the literature compared to studies on mammalian species. This is particularly unfortunate as aquatic...

Year Published: 2021Topics: Abnormal/Problematic Behavior, Husbandry & ManagementAnimal Type: Fish, Other Fish

Citation: Hart, A., Reynolds, Z., Troxell-Smith, S. 2021. Using individual-specific conditioning to reduce stereotypic behaviours: A study on smooth dogfish Mustelus canis in captivity. Journal of Zoo and Aquarium Research, 9(3), 193-199.

Constructing and programming a cost-effective murine running wheel with digital revolution counter

Voluntary wheel running is a valuable metabolic intervention and well-established measure of physical activity in preclinical rodent models. Herein, we describe detailed assembly instructions and provide necessary resources for researchers to build their own running wheels from commercial-off-the-shelf parts and...

Year Published: 2021Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Edwards, J., Olson, B., Marks, D.L. 2021. Constructing and programming a cost-effective murine running wheel with digital revolution counter. Lab Animal 50, 202-204.

Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research

Using animals for research raises ethical concerns that are addressed in project evaluation by weighing expected harm to animals against expected benefit to society. A harm–benefit analysis (HBA) relies on two preconditions: (a) the study protocol is scientifically suitable and...

Year Published: 2021Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Eggel, M., Würbel, H. 2021. Internal consistency and compatibility of the 3Rs and 3Vs principles for project evaluation of animal research. Laboratory Animals 55(3), 233-243.

Clarification of early end-points for refinement of animal experiments, with specific reference to fish

Appropriate end-points are integral to the refinement of laboratory animal experiments. Our recent experience has highlighted that ambiguity around end-points is hampering their adoption in experiments that cause severe suffering to fish. In toxicology, the term endpoint (single word) refers...

Year Published: 2021Topics: Humane Endpoint, Welfare AssessmentAnimal Type: Fish, Other Fish, Salmon, Tilapia, Trout, Zebrafish

Citation: Ellis, T., Katsiadaki, I. 2021. Clarification of early end-points for refinement of animal experiments, with specific reference to fish. Laboratory Animals 55(3), 244-253.