Guinea Pig

Evaluation of pain assessment techniques and analgesia efficacy in a female guinea pig (Cavia porcellus) model of surgical pain

Guinea pigs (Cavia porcellus) are a frequently used species in research, often involving potentially painful procedures. Therefore, evidence-based recommendations regarding analgesia are critically needed to optimize their wellbeing. Our laboratory examined the efficacy of carprofen and extended-release (ER) buprenorphine, alone...

Year Published: 2017Topics: Analgesia, Welfare AssessmentAnimal Type: Guinea Pig, Rodent

Citation: Oliver, V. L., Athavale, S., Simon, K. E. et al. 2017. Evaluation of pain assessment techniques and analgesia efficacy in a female guinea pig (Cavia porcellus) model of surgical pain. JAALAS 56(4), 425-435.

Pharmacokinetics and adverse effects of 3 sustained-release buprenorphine dosages in healthy guinea pigs (Cavia porcellus)

In guinea pigs, studies addressing the efficacy, safety, and pharmacokinetic profiles of different sustained-release buprenorphine (SRB) formulations are still in their infancy. Here we assessed the pharmacokinetic profiles of 3 SRB dosages (SR-LAB, ZooPharm; SRBLow, 0.15 mg/kg; SRBMedium, 0.3 mg/kg;...

Year Published: 2017Topics: AnalgesiaAnimal Type: Guinea Pig, Rodent

Citation: Zanetti, A. S., Putta, S. K., Casebolt, D. B. et al. 2017. Pharmacokinetics and adverse effects of 3 sustained-release buprenorphine dosages in healthy guinea pigs (Cavia porcellus). JAALAS 56(6), 768-778.

Instituting dark-colored cover to improve central space use within guinea pig enclosure

Domestic guinea pigs (Cavia aperea f. porcellus) in laboratories have been shown to actively avoid the centers of their cages. This experiment tested a novel, dark-colored “shader” placed over the central portion of a cage. Based on the observed behavior...

Year Published: 2016Topics: Environmental Enrichment, HousingAnimal Type: Guinea Pig, Rodent

Citation: Byrd, C. P., Winnicker, C., Gaskill, B. N. 2016. Instituting dark-colored cover to improve central space use within guinea pig enclosure. Journal of Applied Animal Welfare Science 19(4), 408-413.

Animal facility videoendoscopic intubation station: Tips and tricks from mice to rabbits

Endotracheal intubation of laboratory animals is a common procedure shared by several research fields for different purposes, such as mechanical ventilation of anaesthetized animals, instillation of cytotoxic nanoparticles, infectious agents or tumour cells for induction of disease models, and even...

Year Published: 2017Topics: Cannulation, Catheterization, & IntubationAnimal Type: Guinea Pig, Mouse, Rabbit, Rat, Rodent

Citation: Miranda, A., Pego, J. M., Correia-Pinto, J. 2017. Animal facility videoendoscopic intubation station: Tips and tricks from mice to rabbits. Laboratory Animals 51(2), 204-207.

The gingival vein as a minimally traumatic site for multiple blood sampling in guinea pigs and hamsters

Laboratory animals are still necessary in scientific investigation and vaccine testing, but while novel methodological approaches are not available for their replacement, the search for new, humane, easy, and painless methods is necessary to diminish their stress and pain. When...

Year Published: 2017Topics: Biological Sampling & Physiological MeasurementAnimal Type: Guinea Pig, Hamster, Rodent

Citation: Rodrigues, M. V., de Castro, S. O., de Albuquerque, C. Z. 2017. The gingival vein as a minimally traumatic site for multiple blood sampling in guinea pigs and hamsters. PLOS ONE 12(5), e0177967.

Repeated anaesthesia with isoflurane and medetomidine-midazolam-fentanyl in guinea pigs and its influence on physiological parameters

Repeated anaesthesia may be required in experimental protocols and in daily veterinary practice, but anaesthesia is known to alter physiological parameters in GPs (Cavia porcellus, GPs). This study investigated the effects of repeated anaesthesia with either medetomidine-midazolam-fentanyl (MMF) or isoflurane...

Year Published: 2017Topics: Anesthesia & SedationAnimal Type: Guinea Pig, Rodent

Citation: Schmitz, S., Tacke, S., Guth, B. et al. 2017. Repeated anaesthesia with isoflurane and medetomidine-midazolam-fentanyl in guinea pigs and its influence on physiological parameters. PLOS ONE 12(3), e0174423.

Comparison of physiological parameters and anaesthesia specific observations during isoflurane, ketamine-xylazine or medetomidine-midazolam-fentanyl anaesthesia in male guinea pigs

Guinea pigs (GPs) are difficult to anaesthetize successfully, the choices for anaesthesia are limited and physiological parameters are likely to be influenced substantially under anaesthesia. We implanted blood pressure radio-telemetry devices into 16 male GPs and subjected them to anaesthesia...

Year Published: 2016Topics: Anesthesia & SedationAnimal Type: Guinea Pig, Rodent

Citation: Schmitz, S., Tacke, S., Guth, B. et al. 2016. Comparison of physiological parameters and anaesthesia specific observations during isoflurane, ketamine-xylazine or medetomidine-midazolam-fentanyl anaesthesia in male guinea pigs. PLOS ONE 11(9), e0161258.

A study of the spontaneous activity of guinea pigs

Year Published: 1922Animal Type: Guinea Pig, Rodent

Citation: Nicholls, E. E. 1922. A study of the spontaneous activity of guinea pigs. Journal of Comparative Psychology 2, 303-330.

Transfer experiments with guinea-pigs

Year Published: 1927Animal Type: Guinea Pig

Citation: Hadley, C. V. D. 1927. Transfer experiments with guinea-pigs. British Journal of Psychology 18, 189-224.

Noise stress in laboratory rodents. I. Behavioral and endocrine response of mice, rats and guinea pigs.

Noise affects the endocrine system.

Year Published: 1959Animal Type: Guinea Pig, Mouse, Rat, Rodent

Citation: Anthony, A., Ackerman, E., Lloyd, J. A. 1959 . Noise stress in laboratory rodents. I. Behavioral and endocrine response of mice, rats and guinea pigs. Journal of the Acoustical Society of America 31, 1430-1436.