Guinea Pig

Sedation efficacy of midazolam in conjunction with ketamine and alfaxalone in female laboratory guinea pigs (Cavia porcellus)

Guinea pigs have been integral as models used in biomedical research, making significant contributions to nutritional, auditory, immunologic, and hypersensitivity studies, and necessitating the routine need for sedation in laboratory settings. The ketamine-xylazine (KX) combination has been the standard sedation...

Year Published: 2024Topics: Anesthesia & SedationAnimal Type: Guinea Pig, Rodent

Citation: Wharton, K. N., Walsh, C. A., Haulter, M. et al. 2024. Sedation efficacy of midazolam in conjunction with ketamine and alfaxalone in female laboratory guinea pigs (Cavia porcellus). JAALAS 63(5), 572–580.

Effect of adopting a timothy hay–based diet at weaning or in adulthood on urinary tract parameters in strain 13/N guinea pigs (Cavia porcellus)

Type of feed is an important consideration in herbivore colony management, yet limited studies report on the effects of diet on common conditions such as urolithiasis in guinea pigs. Urolithiasis is a well-documented cause of lower urinary tract disease in...

Year Published: 2024Topics: Housing, Husbandry & ManagementAnimal Type: Guinea Pig, Rodent

Citation: Wier, R. C., Flietstra, T. D., Coleman-McCray, J. D. et al. 2024. Effect of adopting a timothy hay–based diet at weaning or in adulthood on urinary tract parameters in strain 13/N guinea pigs (Cavia porcellus). JAALAS 63(4), 385–396.

Guidance on the transport of laboratory animals

Report of the Transport Working Group established by the Laboratory Animal Science Association (LASA)

Year Published: 2005Topics: Relocation & TransportAnimal Type: Amphibian, Cat, Dog, Ferret, Frog & Toad, Guinea Pig, Hamster, Macaque, Marmoset, Mouse, Nonhuman Primate, Pig, Rabbit, Rat, Rodent, Salamander

Citation: Swallow, J., Anderson, D., Buckwell, A. C. et al. 2005. Guidance on the transport of laboratory animals. Laboratory Animals 39(1), 1-39.

Measuring ramp use in guinea pigs (Cavia porcellus)

To investigate the utility of ramps as enrichment and as a method for establishing demand for commodities, the latency to climb a ramp of increasing slope to obtain food was measured in four guinea pigs. The average height where guinea...

Year Published: 2022Topics: HousingAnimal Type: Guinea Pig, Rodent

Citation: Begum-Diamond, Z., Neuhauser, J. E., Cameron, K. E. 2022. Measuring ramp use in guinea pigs (Cavia porcellus). Journal of the Experimental Analysis of Behavior 118(2), 292-301.

Thirty years of telemetry-based data acquisition for cardiovascular drug safety evaluation: Applications and optimization

Conducting safety evaluations of new drugs using conscious animals has been a specialty of our working group for thirty years. In this article, we review the various technical challenges and solutions dealt with over the years to improve both the...

Year Published: 2023Topics: Biological Sampling & Physiological Measurement, External Bodily EquipmentAnimal Type: Dog, Guinea Pig, Macaque, Mouse, Nonhuman Primate, Pig, Rat, Rodent

Citation: Alizadeh, E. A., Graf, K., Schiwon, J. et al. 2023. Thirty years of telemetry-based data acquisition for cardiovascular drug safety evaluation: Applications and optimization. Journal of Pharmacological and Toxicological Methods 122, 107279.

Comparison of subcutaneous sedation with alfaxalone or alfaxalone-midazolam in pet guinea pigs (Cavia porcellus) of three different age groups

OBJECTIVE To compare the cardiorespiratory effects, quality and duration of sedation of 2 subcutaneous sedation protocols for noninvasive procedures in guinea pigs (GPs). ANIMALS 24 pet GPs (15 females, 9 males) of 3 different age groups: infant (n = 8),...

Year Published: 2022Topics: Anesthesia & SedationAnimal Type: Guinea Pig, Rodent

Citation: Álvarez, E. R., Solé, L. V., Mateo, A. G. de C. 2022. Comparison of subcutaneous sedation with alfaxalone or alfaxalone-midazolam in pet guinea pigs (Cavia porcellus) of three different age groups. Journal of the American Veterinary Medical Association 260(9), 1024–1030.

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals (9th ed.)

The latest edition of the seminal reference on the care and management of laboratory and research animals. The newly revised ninth edition of The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals delivers an up-to-date...

Year Published: 2024Topics: Animal Training, Environmental Enrichment, Euthanasia, Housing, Husbandry & Management, Natural Behavior, Relocation & Transport, Welfare AssessmentAnimal Type: Amphibian, Bird, Capuchin, Cat, Cattle, Cephalopod, Crustacean, Dog, Equine, Ferret, Finch, Fish, Fowl, Frog & Toad, Gerbil, Goat, Guinea Pig, Hamster, Invertebrate, Lizard, Macaque, Marmoset, Mole Rat, Mouse, Nonhuman Primate, Other Animal, Other Bird, Other Fish, Other Nonhuman Primate, Other Rodent, Pig, Rabbit, Rat, Reptile, Rodent, Sheep, Snake, Tree Shrew, Turtle & Tortoise, Vervet (African Green Monkey), Zebrafish

Citation: Golledge, H., Richardson, C. (Eds.) 2024. The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals (9th ed.). Wiley-Blackwell. 1040 p.

Effects of castration and sterilization on baseline and response levels of cortisol—A case study in male guinea pigs

An uncontrolled reproduction of animals in human hands should be avoided. To meet this goal, animals are widely castrated, i.e., the gonads are completely removed. Since the gonads are the most important source of sex hormones, this is a serious...

Year Published: 2023Topics: Body Modification/Mutilation, ReproductionAnimal Type: All/General, Guinea Pig, Rodent

Citation: Kaiser, S., Korte, A., Wistuba, J. et al. 2023. Effects of castration and sterilization on baseline and response levels of cortisol—A case study in male guinea pigs. Frontiers in Veterinary Science 9, 1093157.

Review of rat (Rattus norvegicus), Mouse (Mus musculus), Guinea pig (Cavia procellus), and rabbit (Oryctolagus cuniculus) indicators for welfare assessment

The monitoring and assessment of animals is important for their health and welfare. The appropriate selection of multiple, validated, and feasible welfare assessment indicators is required to effectively identify compromises or improvements to animal welfare. Animal welfare indicators can be...

Year Published: 2023Topics: Welfare AssessmentAnimal Type: Guinea Pig, Mouse, Rabbit, Rat, Rodent

Citation: Cohen, S., Ho, C. 2023. Review of rat (Rattus norvegicus), Mouse (Mus musculus), Guinea pig (Cavia procellus), and rabbit (Oryctolagus cuniculus) indicators for welfare assessment. Animals 13(13), 2167.

The evolution of how guinea pigs are housed at high containment in the Biological Investigations Group

Previously, we housed guinea pigs in pairs, where study design allowed, using RC2R cages (NKP-Isotec). Our change was to house guinea pigs in bigger groups with more space. This resulted in moving the guinea pigs into a floor pen, which...

Year Published: 2022Topics: HousingAnimal Type: Guinea Pig, Rodent

Citation: Emm, L., Heydon, J. 2022. The evolution of how guinea pigs are housed at high containment in the Biological Investigations Group. Animal Technology and Welfare 21(2), 137-140.