Biological Sampling & Physiological Measurement

Jacketed telemetry in rats: A novel non-invasive method for cardiorespiratory phenotyping during treadmill exercise

The development of alternative methods for monitoring cardiorespiratory function without restraint or surgical implantation is attracting growing interest for both ethical and scientific reasons. For this purpose, a new non-invasive jacketed telemetry tool consisting in a radio device maintained in...

Year Published: 2025Topics: Biological Sampling & Physiological Measurement, External Bodily EquipmentAnimal Type: Rat, Rodent

Citation: Tanguy, S., Cambier, A., Fontana-Pires, L. et al. 2025. Jacketed telemetry in rats: A novel non-invasive method for cardiorespiratory phenotyping during treadmill exercise. Laboratory Animals 59(2), 215–225.

Inconsistent terminology in rodent anatomy hinders appropriate blood sampling in laboratory animal science: A review of blood sampling techniques on the head of mice

Blood sampling is often performed during animal studies. This is more challenging in mice than in larger animal species owing to their size and lack of blood vessel visibility. Guidelines for blood sampling in mice and papers on animal welfare...

Year Published: 2025Topics: Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rodent

Citation: Štrbenc, M. 2025. Inconsistent terminology in rodent anatomy hinders appropriate blood sampling in laboratory animal science: A review of blood sampling techniques on the head of mice. Laboratory Animals 59(3), 332–341.

Exploring the utility of the gut microbiome as a longitudinal health monitoring tool in sanctuary chimpanzees (Pan troglodytes)

The primary goal of captive primate management is to ensure optimal health and welfare of the animals in our care. Given that the gut microbiome interacts closely with host metabolism, immunity, and even cognition, it represents a potentially powerful tool...

Year Published: 2025Topics: Biological Sampling & Physiological Measurement, Husbandry & ManagementAnimal Type: Chimpanzee, Nonhuman Primate

Citation: Amato, K. R., Lake, B. R., Ozminkowski, S. et al. 2025. Exploring the utility of the gut microbiome as a longitudinal health monitoring tool in sanctuary chimpanzees (Pan troglodytes). American Journal of Primatology 87(3), e70004.

Impact of enrichment of metabolic cages with ball-shaped shelters in studies of protein metabolism in rats (Rattus norvegicus)

Housing in metabolic cages for quantitative collection of urine and feces is necessary for nitrogen (N) metabolism studies but may have negative consequences for rat welfare. We hypothesized that providing shelters in metabolic cages would affect the rats’ behavior and...

Year Published: 2025Topics: Biological Sampling & Physiological Measurement, Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Lærke, H. N., Ternman, E. M., Stødkilde, L. et al. 2025. Impact of enrichment of metabolic cages with ball-shaped shelters in studies of protein metabolism in rats (Rattus norvegicus). Journal of the American Association for Laboratory Animal Science 64(2), 301–309.

Impact of an implanted intra-abdominal telemetry transmitter on fecal excretion of corticosterone and IgA in adult male F344 and BN rats (Rattus norvegicus)

Telemetry is a widely used method for obtaining physiologic data from rats, but it is uncertain how distressing it is for the animals to live with an implanted transmitter for long periods. The present study aimed to assess this impact...

Year Published: 2025Topics: Biological Sampling & Physiological MeasurementAnimal Type: Rat, Rodent

Citation: Kemppinen, N., Meller, A., Kalliokoski, O. et al. 2025. Impact of an implanted intra-abdominal telemetry transmitter on fecal excretion of corticosterone and IgA in adult male F344 and BN rats (Rattus norvegicus). Journal of the American Association for Laboratory Animal Science 64(3), 495–499.

Infrared thermography for temperature measurement in adult female C57BL/6NCrl mice: A comparison with rectal probe and subcutaneous transponder

Body temperature is an easily measured clinical parameter that provides important information about an animal’s health and welfare. In the context of animal experiments, temperature monitoring provides relevant data needed to manage animal care and has been embraced as a...

Year Published: 2025Topics: Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rodent

Citation: Fiebig, K., Jourdan, T., Kock, M. et al. 2025. Infrared thermography for temperature measurement in adult female C57BL/6NCrl mice: A comparison with rectal probe and subcutaneous transponder. Journal of the American Association for Laboratory Animal Science 64(1), 120–131.

Contactless monitoring of respiratory rate variability in rats under anesthesia with a compact 24GHz microwave radar sensor (2025)

Objective The objective of this study was to develop and validate a noncontact monitoring system for respiratory rate variability in rats under anesthesia using a 24GHz microwave radar sensor. This study aimed to address the need for stress-free monitoring techniques...

Year Published: 2025Topics: Anesthesia & Sedation, Biological Sampling & Physiological MeasurementAnimal Type: Rat, Rodent

Citation: Sun, G., Kurosawa, M., Ninomiya, Y. et al. 2025. Contactless monitoring of respiratory rate variability in rats under anesthesia with a compact 24GHz microwave radar sensor. Frontiers in Veterinary Science 12.

Blood sampling in Göttingen minipigs—a case study of two standard methods and clicker training as a restraint-free alternative (2025)

Blood sampling often requires restraint that negatively affects animal welfare. This case study evaluated three methods for jugular vein blood sampling (V-bench, sling, and clicker training) with the overall aim of assessing the negative impact on animal welfare and providing...

Year Published: 2025Topics: Animal Training, Biological Sampling & Physiological Measurement, RestraintAnimal Type: Pig

Citation: Schiøler, K., Jensen, M. L., Sørensen, D. B. 2025. Blood sampling in Göttingen minipigs—a case study of two standard methods and clicker training as a restraint-free alternative. Animals 15(3), 407.

Tracking ‘tails’: Refining motor activity monitoring in rats and mice (2025)

Motor activity monitoring is used in specialist regulatory toxicology studies to investigate test item related neurobehavioral effects. Introduction of a new video tracking software system which detects the centre point, tail base and nose tip of rodents to individually track...

Year Published: 2025Topics: Behavioral & Cognitive Testing, Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rat, Rodent

Citation: Reading, R. 2025. Tracking “tails”: Refining motor activity monitoring in rats and mice. Animal Technology and Welfare 24(1), 53–56.

Hematological reference intervals for Danish crossbred Landrace Yorkshire Duroc (LYD) pigs used in biomedical research (2025)

The health and welfare of pigs used in biomedical research is essential to research quality and compliance with the 3Rs (replacement, reduction, and refinement). Hematological variables are objective markers to quantitatively determine health issues and evaluate physiological differences before and...

Year Published: 2025Topics: Biological Sampling & Physiological Measurement, Welfare AssessmentAnimal Type: Pig

Citation: Præstegaard, K. F., Winther-Larsen, A., Kousholt, B. S. 2025. Hematological reference intervals for Danish crossbred Landrace Yorkshire Duroc (LYD) pigs used in biomedical research. Acta Veterinaria Scandinavica 67(1), 11.