Publications

Minimally invasive electrocorticography (ECoG) recording in common marmosets

Background: Electrocorticography (ECoG) provides a valuable compromise between spatial and temporal resolution for recording brain activity with excellent signal quality, crucial for presurgical epilepsy mapping and advancing neuroscience, including brain-machine interface development. ECoG is particularly effective in the common marmoset...

Year Published: 2025Topics: Imaging & Electrophysiological RecordingAnimal Type: Marmoset, Nonhuman Primate

Citation: Spadacenta, S., Dicke, P. W., Thier, P. 2025. Minimally invasive electrocorticography (ECoG) recording in common marmosets. Journal of Neuroscience Methods 417, 110409.

Application of the horse grimace scale in horses with dental disease: Preliminary findings

Background Dental disease is a common but often under-recognised condition in horses, possibly due to an inability to recognise clinical signs of oral discomfort. Some dental disorders are reportedly more painful than others, but there is no current metric by...

Year Published: 2025Topics: Disease/Experimental Model, Welfare AssessmentAnimal Type: Equine

Citation: Sidwell, A. E., Duz, M., Hill, B. et al. 2025. Application of the horse grimace scale in horses with dental disease: Preliminary findings. Veterinary Record 196(3), e4800.

Development of a non-invasive novel individual marmoset holder for evaluation by awake functional magnetic resonance brain imaging

Background: Although functional MRI (fMRI) in awake marmosets (Callithrix jacchus) is fascinating for functional brain mapping and evaluation of brain disease models, it is difficult to launch awake fMRI on scanners with bore sizes of less than 16 cm. A universal...

Year Published: 2025Topics: Imaging & Electrophysiological RecordingAnimal Type: Marmoset, Nonhuman Primate

Citation: Seki, F., Yurimoto, T., Kamioka, M. et al. 2025. Development of a non-invasive novel individual marmoset holder for evaluation by awake functional magnetic resonance brain imaging. Journal of Neuroscience Methods 417, 110390.

Mouse strain-specific habituation to oral metamizole administration

When pain might occur during an animal experiment, sufficient analgesia is necessary. Metamizole is the third most used postoperative pain medication in animal research. The analgesic effect of metamizole is supposed to last 6–8 h in rodents. Therefore, the supplementation of...

Year Published: 2025Topics: Drug/Substance AdministrationAnimal Type: Mouse, Rodent

Citation: Schreiber, T., Leitner, E., Brandstetter, J. et al. 2025. Mouse strain-specific habituation to oral metamizole administration. Laboratory Animals 59(2), 192–202.

Breeding planning for laboratory mice

In laboratory animal facilities, due to the rules of mammalian genetics, animals are often produced that do not possess the required genotype for planned experiments. To minimize the number of these animals that cannot be used for the intended research,...

Year Published: 2025Topics: ReproductionAnimal Type: Mouse, Rodent

Citation: Schenkel, J., Nagel-Riedasch, S., Zevnik, B. et al. 2025. Breeding planning for laboratory mice. Laboratory Animals 59(3), 415–415.

Physiologic consequences of housing adult male cynomolgus monkeys (Macaca fascicularis) in heterosexual pairs: A pilot study using implanted biotelemetry

Facilities may forgo attempting to socially house adult males due to fear of animal injury, study disruptions, and confounding data results. To leverage the potential advantages of male–female pairs, and to understand the impact on measures typically used in safety...

Year Published: 2025Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Santos, R., Tran, D.-B., Li, D. et al. 2025. Physiologic consequences of housing adult male cynomolgus monkeys (Macaca fascicularis) in heterosexual pairs: A pilot study using implanted biotelemetry. American Journal of Primatology 87(6), e70052.

Key concepts for enhancing zoo animal welfare: Coping, comfort, choice, control, challenge, and compassion

Zoo animal welfare is subject to increasing scrutiny by many audiences. Although zoo husbandry and management techniques have progressed, common welfare issues are still apparent. To encourage further improvements, converting theoretical welfare definition into practical application is key. This paper...

Year Published: 2025Topics: Natural Behavior, Welfare AssessmentAnimal Type: All/General

Citation: Rose, P. E., Lewton, J. 2025. Key concepts for enhancing zoo animal welfare: Coping, comfort, choice, control, challenge, and compassion. Journal of Applied Animal Welfare Science 28(3), 497–514.

Decision trees for determining the fate of laboratory animals

Facilities involved in laboratory animal research often face ethical challenges such as: what should I do with the animals that are no longer suitable for experimental purposes? One of the common answers to this question is to kill them. And...

Year Published: 2025Topics: Euthanasia, Relocation & Transport, ReproductionAnimal Type: All/General

Citation: Reshetnykov, M., Stumm, K., Zwick, M. et al. 2025. Decision trees for determining the fate of laboratory animals. Laboratory Animals 59(2), 157–168.

Retrospective descriptive report comparing access systems to refine intravenous self-administration in rats

For operant self-administration, permanent intravenous cannulas need to remain open and operational for months without infections or blockages. Here, we report retrospectively on our experiences and observations using different access systems during three studies. We identified a refined method for...

Year Published: 2025Topics: Cannulation, Catheterization, & Intubation, Social Housing & CompanionshipAnimal Type: Rat, Rodent

Citation: Lozeman-van ’t Klooster, J. G., Lesscher, H. M. 2025. Retrospective descriptive report comparing access systems to refine intravenous self-administration in rats. Laboratory Animals 59(3), 364–368.

Current research and guidelines for euthanasia in laboratory fish with a focus on fathead minnows

This paper reviews the methods and approaches used to humanely anesthetize (render unconscious) and or euthanize (kill) laboratory fish (in research settings), with a specific focus on the fathead minnow. We surveyed the literature (333 scientific studies published 2004–2021) to...

Year Published: 2025Topics: EuthanasiaAnimal Type: Fish, Other Fish

Citation: Lavalle, C., Clarence, S., Khan, H. et al. 2025. Current research and guidelines for euthanasia in laboratory fish with a focus on fathead minnows. Laboratory Animals 59(3), 319–331.