Publications

Design by intravenous injection in the Syrian hamster

Repeated injections in rats and mice are typically done via the tail vein. For hamsters, the tail is not an option. In this paper we explore the development and refinement of IV dosing in the Syrian hamster via the jugular...

Year Published: 2018Topics: Drug/Substance AdministrationAnimal Type: Hamster, Rodent

Citation: Beamish, G., Chapman, C., Lomax, A. 2018. Design by intravenous injection in the Syrian hamster. Animal Technology and Welfare 17(2), 124-125.

Refinements to animal husbandry for continuous infusion dosing in Beagle dogs

At Envigo we are contracted by our customers to conduct studies, usually to evaluate the safety of new drugs and chemicals. A rodent and non-rodent species are usually involved in this testing with the method of administration designed to replicate...

Year Published: 2018Topics: External Bodily EquipmentAnimal Type: Dog

Citation: Allen, L. 2018. Refinements to animal husbandry for continuous infusion dosing in Beagle dogs. Animal Technology and Welfare 17(2), 126-127.

Refining mouse handling – do we or don’t we? An animal technologist’s perspective

Recent research in the industry identified that picking up mice in a tunnel or cupping them in the hand significantly reduces their stress levels. As Animal Tecgnologists, we could see advantages and disadvantages with this change for the animals, staff...

Year Published: 2018Topics: HandlingAnimal Type: Mouse, Rodent

Citation: Swan, A. 2018. Refining mouse handling - do we or don't we? An animal technologist's perspective. Animal Technology and Welfare 17(2), 130-131.

Introduction of gang caging for group housed rats

Using an existing gang cage designed for ferrets, we developed a version that would be suitable for housing rats. Caging consisted of 3 floors with a combined floor area of 11620m, connected by 2 ladders. Each individual unit can be...

Year Published: 2018Topics: Environmental Enrichment, HousingAnimal Type: Rat, Rodent

Citation: Clarke, D., Ioannou, L. 2018. Introduction of gang caging for group housed rats. Animal Technology and Welfare 17(2), 136-137.

Spider and chips: The use of internal Radio Frequency Identification (RFID) chips as a minimally invasive method to measure internal body temperatures in invertebrates

Internal RFID transponders have been used in vertebrates for many years, however studies into their use in invertebrates are less well represented in the literature. The use of RFID transponders for internal temperature measurement represents a less invasive alternative to...

Year Published: 2018Topics: Biological Sampling & Physiological Measurement, External Bodily EquipmentAnimal Type: Insect & Spider, Invertebrate

Citation: Baker, S., Knight, E., Pellett, S. et al. 2018. Spider and chips: The use of internal Radio Frequency Identification (RFID) chips as a minimally invasive method to measure internal body temperatures in invertebrates. Animal Technology and Welfare 17(1), 1-7.

Synchronisation of oestrous cycle on C57BL/6J mice after the introduction of a hanging perforated container with bedding soaked by the excretions of male mice

Synchronisation of oestrous cycle is a commonly used method to manage pregnancies either for breeding or for research purposes. Based on Whitten effect, the aim of our study was to introduce a new refined method for oestrous synchronisation and to...

Year Published: 2018Topics: ReproductionAnimal Type: Mouse, Rodent

Citation: Balafas, E., Stasinopoulou, M., Alexakos, P. et al. 2018. Synchronisation of oestrous cycle on C57BL/6J mice after the introduction of a hanging perforated container with bedding soaked by the excretions of male mice. Animal Technology and Welfare 17(1), 9-11.

Measuring physiological stress in the common marmoset (Callithrix jacchus): Validation of a salivary cortisol collection and assay technique

Cortisol levels are often used as a physiological measure of the stress response in captive primates, with noninvasive measures of this being an important step in welfare assessment. We report a method of collecting saliva samples voluntarily from unrestrained captive...

Year Published: 2018Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Ash, H., Smith, T. E., Knight, S. et al. 2018. Measuring physiological stress in the common marmoset (Callithrix jacchus): Validation of a salivary cortisol collection and assay technique. Physiology & Behavior 185, 14-22.

Behavioral responses of CD-1 mice to conspecific and heterospecific blood odors and to a blood odor component

The odor of blood may have both aversive and attractive properties for mammals, depending on the species of the odor donor and the species perceiving the odor. To better understand the informational content of blood odor for a prey species...

Year Published: 2018Topics: EuthanasiaAnimal Type: Mouse, Rodent

Citation: Lahger, C., Laska, M. 2018. Behavioral responses of CD-1 mice to conspecific and heterospecific blood odors and to a blood odor component. Physiology & Behavior 184, 2015-210.

Vocal correlates of emotional reactivity within and across contexts in domestic pigs (Sus scrofa)

Vocalizations have long been recognized to encode information about an individual's emotional state and, as such, have contributed to the study of emotions in animals. However, the potential of vocalizations to also encode information about an individual's emotional reactivity has...

Year Published: 2017Topics: Vocalization, Welfare AssessmentAnimal Type: Pig

Citation: Leliveld, L. M. C., Düpjan, S., Tuchscherer, A. et al. 2017. Vocal correlates of emotional reactivity within and across contexts in domestic pigs (Sus scrofa). Physiology & Behavior 181, 117-126.

Assessing the exploratory and anxiety-related behaviors of mice

Ample studies have shown that housing can affect the health, welfare and behavior of mice and therefore, the outcomes of certain experiments. The aim of this study was to investigate if three widely used housing systems, Open Top Cages (OTC),...

Year Published: 2017Topics: Emotion, Pain, & Sentience, HousingAnimal Type: Mouse, Rodent

Citation: Polissidis, A., Zelelak, S., Nikita, M. et al. 2017. Assessing the exploratory and anxiety-related behaviors of mice. Do different caging systems affect the outcome of behavioral tests? Physiology & Behavior 177, 68-73.