Publications

Mission creep or mission lapse? Scientific review in research oversight

Background: The ethical use both of human and non-human animals in research is predicated on the assumption that it is of a high quality and its projected benefits are more significant than the risks and harms imposed on subjects. Yet...

Year Published: 2023Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Waltz, M., Fisher, J. A., Walker, R. L. 2023. Mission creep or mission lapse? Scientific review in research oversight. AJOB Empirical Bioethics 14(1), 38-49.

Ultrasonic vocalizations near 30 kHz may indicate excitement rather than distress in female Wistar rats

Rats emit ultrasonic vocalizations (USVs), sometimes referred to as 50-kHz vocalizations, during activities such as play and lower-frequency USVs, sometimes referred to as 22-kHz vocalizations, when experiencing distress. Definitions of 22-kHz vocalizations vary in terms of which frequencies should be...

Year Published: 2023Topics: Emotion, Pain, & Sentience, VocalizationAnimal Type: Rat, Rodent

Citation: Lupfer, G., Brandenburger, A., Machado, M. et al. 2023. Ultrasonic vocalizations near 30 kHz may indicate excitement rather than distress in female Wistar rats. Applied Animal Behaviour Science 261, 105881.

Run access, hutch size and time-of-day affect welfare-relevant behaviour and faecal corticosterone in pair-housed pet rabbits

Although there exist several studies examining the housing needs of rabbits kept in laboratories and for meat, studies of the requirements of pet rabbits are few and focus entirely on single rabbits. Pet rabbits are recommended to be kept in...

Year Published: 2023Topics: HousingAnimal Type: Rabbit

Citation: Rooney, N. J., Baker, P. E., Blackwell, E.-J. et al. 2023. Run access, hutch size and time-of-day affect welfare-relevant behaviour and faecal corticosterone in pair-housed pet rabbits. Applied Animal Behaviour Science 262, 105919.

Species specific differences in short-term behavioral reaction of voles to cage elements removal

The welfare of animals used in scientific experiments should be one of the most important things to take care of. Many kinds of research show that the enriching elements can help animals to fulfil their natural behaviour. However, those studies...

Year Published: 2023Topics: Environmental EnrichmentAnimal Type: Other Rodent, Rodent

Citation: Kapusta, J., Siewierska, D., Kruczek, M. et al. 2023. Species specific differences in short-term behavioral reaction of voles to cage elements removal. Applied Animal Behaviour Science 262, 105899.

Psychosocial stress alters the immune response and results in higher viral load during acute simian immunodeficiency virus infection in a pigtailed macaque model of human immunodeficiency virus

Although social distancing is a key public health response during viral pandemics, psychosocial stressors, such as social isolation, have been implicated in adverse health outcomes in general [1] and in the context of infectious disease, such as human immunodeficiency virus...

Year Published: 2021Topics: Disease/Experimental Model, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Guerrero-Martin, S. M., Rubin, L. H., McGee, K. M. et al. 2021. Psychosocial stress alters the immune response and results in higher viral load during acute simian immunodeficiency virus infection in a pigtailed macaque model of human immunodeficiency virus. The Journal of Infectious Diseases 224(12), 2113–2121.

Conventional laboratory housing increases morbidity and mortality in research rodents: Results of a meta-analysis

Over 120 million mice and rats are used annually in research, conventionally housed in shoebox-sized cages that restrict natural behaviours (e.g. nesting and burrowing). This can reduce physical fitness, impair thermoregulation and reduce welfare (e.g. inducing abnormal stereotypic behaviours). In...

Year Published: 2022Topics: Disease/Experimental Model, Environmental Enrichment, HousingAnimal Type: Mouse, Rat, Rodent

Citation: Cait, J., Cait, A., Scott, R. W. et al. 2022. Conventional laboratory housing increases morbidity and mortality in research rodents: Results of a meta-analysis. BMC Biology 20(1), 15.

Nature calls: Intelligence and natural foraging style predict poor welfare in captive parrots

Understanding why some species thrive in captivity, while others struggle to adjust, can suggest new ways to improve animal care. Approximately half of all Psittaciformes, a highly threatened order, live in zoos, breeding centres and private homes. Here, some species...

Year Published: 2021Topics: Abnormal/Problematic Behavior, Husbandry & ManagementAnimal Type: Bird, Parrot

Citation: Mellor, E. L., McDonald Kinkaid, H. K., Mendl, M. T. et al. 2021. Nature calls: Intelligence and natural foraging style predict poor welfare in captive parrots. Proceedings of the Royal Society B: Biological Sciences 288(1960), 20211952

Blood pressure monitoring in zoologically managed bonobos (Pan paniscus)

In response to the growing evidence that hypertension may play a significant role in the development of cardiovascular disease (CVD) in bonobos, the Great Ape Heart Project established a finger blood pressure (BP) monitoring protocol for zoo-housed bonobos. The ability...

Year Published: 2023Topics: Biological Sampling & Physiological MeasurementAnimal Type: Nonhuman Primate, Other Nonhuman Primate

Citation: Danforth, M. D., Clyde, V. L., Jourdan, B. et al. 2023. Blood pressure monitoring in zoologically managed bonobos (Pan paniscus). American Journal of Primatology 85(3), e23474.

Reducing stress and stereotypic behaviors in captive female pygmy slow lorises (Nycticebus pygmeaus)

Improving captive conditions of pygmy slow lorises (Nekaris and Nijman have recently suggested that the pygmy slow loris should be called the pygmy loris and is distinctive enough to warrant a new genus, Xanthonycticebu) (Nycticebus pygmeaus) poses many challenges because...

Year Published: 2023Topics: Abnormal/Problematic Behavior, Biological Sampling & Physiological Measurement, Social Housing & CompanionshipAnimal Type: Nonhuman Primate, Other Nonhuman Primate

Citation: Alejandro, J., Yamanashi, Y., Nemoto, K. et al. 2023. Reducing stress and stereotypic behaviors in captive female pygmy slow lorises (Nycticebus pygmeaus). American Journal of Primatology 85(7), e23495.

Comparative study of pain-related responses of male piglets up to seven days of age to the application of different local anaesthetics and subsequent castration

To evaluate pain responses to intratesticular and subscrotal injection of three local anaesthetics and their efficacy during castration a randomized controlled study was conducted. In groups of 20 piglets, procaine (2%), lidocaine (2%), or mepivacaine (2%) were administered subscrotal and...

Year Published: 2022Topics: Anesthesia & Sedation, Body Modification/MutilationAnimal Type: Pig

Citation: Söbbeler, F. J., Wendt, S., Briese, A. et al. 2022. Comparative study of pain-related responses of male piglets up to seven days of age to the application of different local anaesthetics and subsequent castration. Animals 12(20), 2833.