Publications

Evaluation of ambient sound, vibration, and light in rodent housing rooms

Excessive sound, vibration, and light are detrimental to rodent welfare, yet these parameters are rarely recorded in vivaria. Whether housing environments exceed the suggested thresholds and which specific factors may alter these parameters is generally unknown. The goal of this...

Year Published: 2022Topics: Husbandry & ManagementAnimal Type: Mouse, Rat, Rodent

Citation: Barabas, A. J., Darbyshire, A. K., Schlegel, S. L. et al. 2022. Evaluation of ambient sound, vibration, and light in rodent housing rooms. JAALAS 61(6), 660–671.

Pinna edge biopsy of 7 and 21 day old C57BL/6 mice as a method for identification and genotyping

Identifying and genotyping mice prior to weaning can be useful for mouse colony management. Mice of an undesired genotype can be identified prior to weaning and removed from further study, resulting in a reduction of housing costs, and labor time....

Year Published: 2023Topics: Identification MethodAnimal Type: Mouse, Rodent

Citation: Chen, D. D., Molk, D. M., Palley, L. S. et al. 2023. Pinna edge biopsy of 7 and 21 day old C57BL/6 mice as a method for identification and genotyping. JAALAS 62(5), 438–448.

Effects of housing density on reproductive performance, intracage ammonia, and welfare of mice continuously housed as breeders in standard mouse and rat caging

Maintaining compliance with cage density recommendations in The Guide for the Care and Use of Laboratory Animals precludes continuous trio breeding in standard-sized mouse cages. This study evaluated and compared several parameters of reproductive performance, intracage ammonia concentration, and fecal...

Year Published: 2023Topics: Husbandry & Management, Reproduction, Stocking DensityAnimal Type: Mouse, Rodent

Citation: Cho, E., Walsh, C. A., D'Angelo-Gavrish, N. M. et al. 2023. Effects of housing density on reproductive performance, intracage ammonia, and welfare of mice continuously housed as breeders in standard mouse and rat caging. JAALAS 62(2), 116–122.

The effect of noise, vibration, and light disturbances from daily health checks on breeding performance, nest building, and corticosterone in mice

At our institution, the techniques that technicians use for health checks vary for mice housed in cages on individually ventilated caging (IVC) racks. If the mice cannot be adequately visualized, some technicians partially undock the cage whereas others use an...

Year Published: 2023Topics: Emotion, Pain, & Sentience, Husbandry & Management, ReproductionAnimal Type: Mouse, Rodent

Citation: Clancy, B. M., Theriault, B. R., Turcios, R. et al. 2023. The effect of noise, vibration, and light disturbances from daily health checks on breeding performance, nest building, and corticosterone in mice. JAALAS 62(4), 291–302.

Vivarium lighting as an important extrinsic factor influencing animal-based research

Light is an extrinsic factor that exerts widespread influence on the regulation of circadian, physiologic, hormonal, metabolic, and behavioral systems of all animals, including those used in research. These wide-ranging biologic effects of light are mediated by distinct photoreceptors, the...

Year Published: 2023Topics: Husbandry & ManagementAnimal Type: All/General

Citation: Dauchy, R. T., Blask, D. E. 2023. Vivarium lighting as an important extrinsic factor influencing animal-based research. JAALAS 62(1), 3–25.

Efficacy of supplemental diet gels for preventing postoperative weight loss in mice (Mus musculus)

This study investigated whether the use of commercially available diet gels prevented the postoperative weight loss associated with major survival surgery in mice. C57BL/6 mice were divided into 3 groups (n = 9 per group) that received moistened chow pellets...

Year Published: 2023Topics: Husbandry & Management, Surgery & Post-OpAnimal Type: Mouse, Rodent

Citation: Gates, K. V., Alamaw, E., Jampachaisri, K. et al. 2023. Efficacy of supplemental diet gels for preventing postoperative weight loss in mice (Mus musculus). JAALAS 62(1), 87–91.

Evaluation of submental blood collection in mice (Mus musculus)

The submental route is an option for nonterminal and serial blood collection in mice. This study compared the submental route to the maxillary route (also referred to as the submandibular route). The study used male CD1 and C57BL/6 strains of...

Year Published: 2023Topics: Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rodent

Citation: George, A. J., Harmsen, B. J., Ford, J. A. et al. 2023. Evaluation of submental blood collection in mice (Mus musculus). JAALAS 62(1), 92–98.

Euthanasia of neonatal rats and mice using carbon monoxide

Minimization of potential pain and distress of rodents undergoing euthanasia is a touchstone of veterinary clinical medicine. Evaluation of this issue in postweanling rodents has supported revisions to the AVMA (American Veterinary Medical Association) Guidelines on Euthanasia in 2020. However,...

Year Published: 2023Topics: EuthanasiaAnimal Type: Mouse, Rat, Rodent

Citation: Hickman, D. L. 2023. Euthanasia of neonatal rats and mice using carbon monoxide. JAALAS 62(3), 274–278.

Effects of isoflurane anesthesia on C57BL/6J pups after cervical dislocation of dams

Inhalant anesthesia is routinely used for cesarian section in many animal species, allowing the safe delivery of neonates and smooth recovery of dams. However, in mice, inhalant anesthesia in cesarean section may be avoided due to fear of negative health...

Year Published: 2023Topics: ReproductionAnimal Type: Mouse, Rodent

Citation: Hunter, C. L., Yang, P., Renner, D. M. et al. 2023. Effects of isoflurane anesthesia on C57BL/6J pups after cervical dislocation of dams. JAALAS 62(5), 449–452.

A review of long-acting parenteral analgesics for mice and rats

Appropriate analgesia is a crucial part of rodent postoperative and postprocedural pain. Providing appropriate analgesia is an ethical obligation, a regulatory requirement, and an essential element of obtaining quality scientific results and conducting reproducible data. Meeting these requirements is facilitated...

Year Published: 2022Topics: Anesthesia & SedationAnimal Type: Mouse, Rat, Rodent

Citation: Huss, M. K., Pacharinsak, C. 2022. A review of long-acting parenteral analgesics for mice and rats. JAALAS 61(6), 595–602.