Rodent

Comparative effects of 1/4-inch and 1/8-inch corncob bedding on cage ammonia levels, behavior, and respiratory pathology of male C57BL/6 and 129S1/Svlm mice

Corncob is a common bedding material used in laboratory rodents, but little is known about differences in the effects of the 2 available sizes on rodent models and health. This study compared the effects of these 2 corncob bedding sizes...

Year Published: 2020Topics: Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Cantara, S. I., Blas-Machado, U., Zhao, X. et al. 2020. Comparative effects of 1/4-inch and 1/8-inch corncob bedding on cage ammonia levels, behavior, and respiratory pathology of male C57BL/6 and 129S1/Svlm mice. JAALAS 59(6), 695-702.

Identification of sick or dead mice (Mus musculus) housed with 6 grams of crinkle paper nesting material

Although nesting material is beneficial to the welfare of laboratory mice, provision of appropriate amounts may impair visualization of the mice. In anticipation of our academic research institution transitioning to providing 6 grams of nesting material to all mice, we...

Year Published: 2021Topics: Husbandry & Management, Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Burlingame, L. A., Gaskill, B. N., Lofgren, J. L. S. 2021. Identification of sick or dead mice (Mus musculus) housed with 6 grams of crinkle paper nesting material. JAALAS 60(1), 18-27.

Indicators of postoperative pain in Syrian hamsters (Mesocricetus auratus)

Despite the use of Syrian hamsters (Mesocricetus auratus) in research, little is known about the evaluation of pain in this species. This study investigated whether the frequency of certain behaviors, a grimace scale, the treat-take-test proxy indicator, body weight, water...

Year Published: 2021Topics: Welfare AssessmentAnimal Type: Hamster, Rodent

Citation: Edmunson, A. M., Duke Boynton, F. D., Rendahl, A. et al. 2021. Indicators of postoperative pain in Syrian hamsters (Mesocricetus auratus). Comparative Medicine 71(1), 76-85.

Evaluation of nutritional gel supplementation in C57BL/6J mice infected with mouse-adapted Influenza A/PR/8/34 virus

Mice are a common animal model for the study of influenza virus A (IAV). IAV infection causes weight loss due to anorexia and dehydration, which can result in early removal of mice from a study when they reach a humane...

Year Published: 2020Topics: Disease/Experimental Model, Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Felgenhauer, J. L., Brune, J. E., Long, M. E. et al. 2020. Evaluation of nutritional gel supplementation in C57BL/6J mice infected with mouse-adapted Influenza A/PR/8/34 virus. Comparative Medicine 70(6), 471-486.

Conspecific presence improves episodic-like memory in rats

A number of studies have provided evidence that animals, including rats, remember past episodes. However, few experiments have addressed episodic-like memory from a social perspective. In the present study, we evaluated Wistar rats in the WWWhen/ELM task as single setups...

Year Published: 2021Topics: Social Housing & CompanionshipAnimal Type: Rat, Rodent

Citation: de França Malheiros, M. A. S., Castelo-Branco, R., de Medeiros, P. H. S. et al 2021. Conspecific presence improves episodic-like memory in rats. Frontiers in Behavioral Neuroscience 14, 572150.

Automated and continuous monitoring of animal welfare through digital alerting

A primary goal in preclinical animal research is respectful and responsible care aimed toward minimizing stress and discomfort while enhancing collection of accurate and reproducible scientific data. Researchers use hands-on clinical observations and measurements as part of routine husbandry procedures...

Year Published: 2020Topics: Disease/Experimental Model, Humane Endpoint, Welfare AssessmentAnimal Type: Mouse, Rat, Rodent

Citation: Do, J. P., Defensor, E. B., Ichim, C. V. et al. 2020. Automated and continuous monitoring of animal welfare through digital alerting. Comparative Medicine 70(4), 313-327.

Prewarming followed by active warming is superior to passive warming in preventing hypothermia for short procedures in adult rats (Rattus norvegicus) under isoflurane anesthesia

General anesthesia is a common procedure in laboratory rats; however, it impairs thermoregulation, rapidly leading to hypothermia as warm core blood is distributed to the cooler periphery. The protective strategy of prewarming before the onset of anesthesia delays hypothermia, but...

Year Published: 2020Topics: Surgery & Post-OpAnimal Type: Rat, Rodent

Citation: Rufiange, M., Leung, V. S.Y., Simpson, K. et al. 2020. Prewarming followed by active warming is superior to passive warming in preventing hypothermia for short procedures in adult rats (Rattus norvegicus) under isoflurane anesthesia. JAALAS 59(4), 377-383.

Improving animal welfare at Newcastle University by introducing the low stress handling of mice

The primary focus of this project was to introduce the low stress handling of mice to Newcastle University and resulting in all researchers and technicians using this method. It aimed to bring a team together, working to promote and communicate...

Year Published: 2020Topics: HandlingAnimal Type: Mouse, Rodent

Citation: Hamilton, E. 2020. Improving animal welfare at Newcastle University by introducing the low stress handling of mice. Animal Technology and Welfare 19(3), 185-194.

Alternative training method using a mouse simulator in intravenous lateral tail vein procedures

The purpose of this study was to reduce or replace mouse cadavers for use in procedural training. All participants had mixed experience in various technical procedures such as oral gavage, intraperitoneal injections, etc., but none had ever carried out intravenous...

Year Published: 2020Topics: Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rodent

Citation: Abela, C. 2020. Alternative training method using a mouse simulator in intravenous lateral tail vein procedures. Animal Technology and Welfare 19(3), 249-250.

Surgery refinements improve success rates in rat bile collection

This poster compares the model success rates using 2 different housing regimes during recovery from surgery. Catheters were placed in the bile duct to collect bile; a second catheter was secured into the duodenum where artificial bile salts were infused....

Year Published: 2020Topics: Cannulation, Catheterization, & IntubationAnimal Type: Rat, Rodent

Citation: Van Wijk, H., Haida, D., Duncan, C. et al. 2020. Surgery refinements improve success rates in rat bile collection. Animal Technology and Welfare 19(3), 251-254.