Rodent

Impact of enrichment of metabolic cages with ball-shaped shelters in studies of protein metabolism in rats (Rattus norvegicus)

Housing in metabolic cages for quantitative collection of urine and feces is necessary for nitrogen (N) metabolism studies but may have negative consequences for rat welfare. We hypothesized that providing shelters in metabolic cages would affect the rats’ behavior and...

Year Published: 2025Topics: Biological Sampling & Physiological Measurement, Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Lærke, H. N., Ternman, E. M., Stødkilde, L. et al. 2025. Impact of enrichment of metabolic cages with ball-shaped shelters in studies of protein metabolism in rats (Rattus norvegicus). Journal of the American Association for Laboratory Animal Science 64(2), 301–309.

Impact of an implanted intra-abdominal telemetry transmitter on fecal excretion of corticosterone and IgA in adult male F344 and BN rats (Rattus norvegicus)

Telemetry is a widely used method for obtaining physiologic data from rats, but it is uncertain how distressing it is for the animals to live with an implanted transmitter for long periods. The present study aimed to assess this impact...

Year Published: 2025Topics: Biological Sampling & Physiological MeasurementAnimal Type: Rat, Rodent

Citation: Kemppinen, N., Meller, A., Kalliokoski, O. et al. 2025. Impact of an implanted intra-abdominal telemetry transmitter on fecal excretion of corticosterone and IgA in adult male F344 and BN rats (Rattus norvegicus). Journal of the American Association for Laboratory Animal Science 64(3), 495–499.

Elastic motivation for circuit running behaviour in captive African striped mice Rhabdomys dilectus: A consumer demand approach

Captive environments often result in repetitive locomotor behaviours in animals, yet the motivation for these behaviours remains poorly understood. We investigated whether circuit running in African striped mice Rhabdomys dilectus represents a necessary coping mechanism or a flexible, cost-sensitive behaviour,...

Year Published: 2025Topics: Abnormal/Problematic BehaviorAnimal Type: Other Rodent, Rodent

Citation: Hartman, K.-J., Joshi, S., Pillay, N. 2025. Elastic motivation for circuit running behaviour in captive African striped mice Rhabdomys dilectus: A consumer demand approach. Applied Animal Behaviour Science 289, 106693.

Effect of novel high-fat diet feeding methods on food wastage, weight gain, hair coat grease accumulation, and scratching behavior in C57BL/6NCrl mice

Soft-pelleted, high-fat diets (HFD) are greasy and crumble easily leading to food wastage and hair coat grease accumulation when mice are fed using commercially available feeders. The ideal HFD feeder design should reduce food wastage, facilitate mouse weight gain, and...

Year Published: 2025Topics: Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Guy, A. R., Klores, M., Prestia, K. et al. 2025. Effect of novel high-fat diet feeding methods on food wastage, weight gain, hair coat grease accumulation, and scratching behavior in C57BL/6NCrl mice. Journal of the American Association for Laboratory Animal Science 64(1), 98–105.

Ge, Y., Alamaw, E. D., Ray, R. R. et al. 2025. Analgesic efficacy of a long-acting transdermal buprenorphine in rats (Rattus norvegicus)

Zorbium is the first long-acting transdermal buprenorphine (LAT-bup) approved by the FDA for relieving postoperative pain in cats for 72 h. This study aimed to investigate LAT-bup’s efficacy for attenuating postoperative mechanical and thermal hypersensitivity in a rat incisional pain...

Year Published: 2025Topics: AnalgesiaAnimal Type: Rat, Rodent

Citation: Ge, Y., Alamaw, E. D., Ray, R. R. et al. 2025. Analgesic efficacy of a long-acting transdermal buprenorphine in rats (Rattus norvegicus). Journal of the American Association for Laboratory Animal Science 64(3), 406–413.

Behavioral or nutritional drive: Which motivation affects rates of food grinding in CD1 mice?

Wire mouse feeders used in laboratory mouse cages typically hold enough food to feed 5 mice for two weeks. However, some mice gnaw the food provided into powder, which they do not ingest. The ground-up food fills the cage, resulting...

Year Published: 2025Topics: Abnormal/Problematic Behavior, Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Gaskill, B. N., Davis, H., Gosselin, R. P. et al. 2025. Behavioral or nutritional drive: Which motivation affects rates of food grinding in CD1 mice? Applied Animal Behaviour Science 284, 106533.

Infrared thermography for temperature measurement in adult female C57BL/6NCrl mice: A comparison with rectal probe and subcutaneous transponder

Body temperature is an easily measured clinical parameter that provides important information about an animal’s health and welfare. In the context of animal experiments, temperature monitoring provides relevant data needed to manage animal care and has been embraced as a...

Year Published: 2025Topics: Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rodent

Citation: Fiebig, K., Jourdan, T., Kock, M. et al. 2025. Infrared thermography for temperature measurement in adult female C57BL/6NCrl mice: A comparison with rectal probe and subcutaneous transponder. Journal of the American Association for Laboratory Animal Science 64(1), 120–131.

Analysis of individually ventilated cage (IVC) microenvironments during 21-d cage change frequency for mice using two different bedding types

The Guide for the Care and Use of Laboratory Animals provides recommendations on sanitation frequencies for rodent caging equipment; however, it allows for performance standards to be used when extending this frequency for individually ventilated cage (IVC) caging. Our institution...

Year Published: 2025Topics: Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Felgenhauer, J. L., Copio, J. N., Suri, A. M. et al. 2025. Analysis of individually ventilated cage (IVC) microenvironments during 21-d cage change frequency for mice using two different bedding types. Journal of the American Association for Laboratory Animal Science 64(2), 259–265.

Assessment of postoperative analgesic efficacy and animal well-being using a novel triaxial accelerometer device, the rodent fitbit-like telemetry device

Accurate postoperative pain management is crucial for good animal welfare and science. We sought to evaluate mouse postoperative pain management efficacy by measuring activity using a novel triaxial acceleration device—the Rodent Fitbit-like telemetry device (RFB)—to monitor home cage activity. To...

Year Published: 2025Topics: Analgesia, Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Campbell, M., Tolwani, A., Tolwani, R. et al. 2025. Assessment of postoperative analgesic efficacy and animal well-being using a novel triaxial accelerometer device, the rodent fitbit-like telemetry device. Journal of the American Association for Laboratory Animal Science 64(3), 457–467.

Light cycle phase effects on behavioral responses to stress exposure in rats

Animal models enable investigation of the impact of stress on emotional-behavioral performance to facilitate understanding of posttraumatic stress symptoms experienced in humans. Refinement of animal stress models could lead to a reduction in the number of subjects needed to detect...

Year Published: 2025Topics: Husbandry & ManagementAnimal Type: Rat, Rodent

Citation: Brown, C. E., Borrell, A. C., DeMar, J. C. et al. 2025. Light cycle phase effects on behavioral responses to stress exposure in rats. Journal of the American Association for Laboratory Animal Science 64(1), 64–75.