Nonhuman Primate

Association of Primate Veterinarians’ Position Statement: Cerebrospinal fluid aspiration for nonhuman primates in biomedical research

The Association of Primate Veterinarians (APV) recognizes that CSF collection may be required for both clinical and research purposes in nonhuman primates (NHP). Because there are inherent risks associated with the technique, the laboratory animal veterinarian should determine the need...

Year Published: 2019Topics: Biological Sampling & Physiological MeasurementAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Association of Primate Veterinarians. 2019. Association of Primate Veterinarians' Position Statement: Cerebrospinal fluid aspiration for nonhuman primates in biomedical research. JAALAS 58(4), 428-429.

Survey of behavioral indices of welfare in research chimpanzees (Pan troglodytes) in the United States

Chimpanzees demand specialized housing and care and the highest degree of attention to animal welfare. The current project used a survey method to collate information on chimpanzee housing and behavioral indices of welfare across all 6 of the chimpanzee research...

Year Published: 2019Topics: Abnormal/Problematic Behavior, Animal Training, Environmental Enrichment, Housing, Husbandry & ManagementAnimal Type: Chimpanzee, Nonhuman Primate

Citation: Bloomsmith, M. A., Clay, A. W., Lambeth, S. P. et al. 2019. Survey of behavioral indices of welfare in research chimpanzees (Pan troglodytes) in the United States. JAALAS 58(2), 160-177.

Evaluation of analgesic patches in cynomolgus macaques (Macaca fascicularis)

Opioids are widely used in veterinary and human medicine to manage pain. However, there is a paucity of information in the literature regarding the pharmacokinetics of opioid transdermal patches (TDP) in NHP. Therefore, to determine whether opioid TDP attain therapeutic...

Year Published: 2019Topics: AnalgesiaAnimal Type: Macaque, Nonhuman Primate

Citation: Smith, A. A., Halliday, L. C., Lindeblad, M. O. et al. 2019. Evaluation of analgesic patches in cynomolgus macaques (Macaca fascicularis). JAALAS 58(3), 356-361.

Association of Primate Veterinarians’ guidelines for nonhuman primate restraint

The Association of Primate Veterinarians (APV) recognizes that several forms of restraint, including physical and chemical, are necessary for the safe handling of nonhuman primates (NHPs). The following guidelines aim to provide information to researchers, animal caregivers, veterinarians, and institutional...

Year Published: 2019Topics: RestraintAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Association of Primate Veterinarians. 2019. Association of Primate Veterinarians' guidelines for nonhuman primate restraint. JAALAS 58(3), 282-284.

Refinements of equipment and methodology to reduce risk during pole-guided chair transfer of nonhuman primates

Neurophysiologic studies of NHP commonly involve their transfer from a housing enclosure to a laboratory by using a mobile chair. This transfer should be performed in a manner that is safe and minimizes stress for both animal and handler. The...

Year Published: 2019Topics: HandlingAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: McIntosh, M. K., Armitage-Brown, B., Levy, R. 2019. Refinements of equipment and methodology to reduce risk during pole-guided chair transfer of nonhuman primates. JAALAS 58(4), 462-468.

Effects of pregnancy, outdoor access, and antifungal medication on hair loss in breeding-age female pigtailed macaques (Macaca nemestrina)

Over 18 mo, adult female pigtailed macaques (Macaca nemestrina) housed at a breeding facility in Arizona were monitored every 6 mo for alopecia. The study period coincided with the movement of a majority of animals from primarily outdoor housing to...

Year Published: 2019Topics: Abnormal/Problematic Behavior, HousingAnimal Type: Macaque, Nonhuman Primate

Citation: Kroeker, R., Chichester, L., Lee, G. H. et al. 2019. Effects of pregnancy, outdoor access, and antifungal medication on hair loss in breeding-age female pigtailed macaques (Macaca nemestrina). Comparative Medicine 69(3), 221–227.

Daily water intake by common marmosets (Callithrix jacchus) and recommendations regarding fluid regulation

The typical daily water intake of common marmosets (Callithrix jacchus) in a research setting has not been well characterized. Because these New World primates are in demand as animal models for neurobehavioral experiments, which can include the potential use of...

Year Published: 2019Topics: Husbandry & Management, Natural BehaviorAnimal Type: Macaque, Nonhuman Primate

Citation: Winn, C. B., Issa, E. B., Curcillo, C. P. et al. 2019. Daily water intake by common marmosets (Callithrix jacchus) and recommendations regarding fluid regulation. JAALAS 58(1), 16-20.

Regional anesthesia for dentistry and orofacial surgery in rhesus macaques (Macaca mulatta)

Regional anesthesia is a commonly used adjunct to orofacial dental and surgical procedures in companion animals and humans. However, appropriate techniques for anesthetizing branches of the mandibular and maxillary nerves have not been described for rhesus monkeys. Skulls of 3...

Year Published: 2019Topics: Anesthesia & Sedation, Disease/Experimental ModelAnimal Type: Macaque, Nonhuman Primate

Citation: Engel, R. M., Thomas III, M. L., Banks, R. E. 2019. Regional anesthesia for dentistry and orofacial surgery in rhesus macaques (Macaca mulatta). JAALAS 58(2), 223-230.

Interest in non-social novel stimuli as a function of age in rhesus monkeys

Human cognitive and affective life changes with healthy ageing; cognitive capacity declines while emotional life becomes more positive and social relationships are prioritized. This may reflect an awareness of limited lifetime unique to humans, leading to a greater interest in...

Year Published: 2019Topics: Environmental EnrichmentAnimal Type: Macaque, Nonhuman Primate

Citation: Bliss-Moreau, E., Baxter, M. G. 2019. Interest in non-social novel stimuli as a function of age in rhesus monkeys. Royal Society Open Science 6(9), 182237.

Minimally invasive lumbar port system for the collection of cerebrospinal fluid from rhesus macaques (Macaca mulatta)

Biomedical translational research frequently incorporates collection of CSF from NHP, because CSF drug levels are used as a surrogate for CNS tissue penetration in pharmacokinetic and dynamic studies. Surgical placement of a CNS ventricular catheter reservoir for CSF collection is...

Year Published: 2016Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: MacAllister, R. P., Lester McCully, C. M., Bacher, J. et al. 2016. Minimally invasive lumbar port system for the collection of cerebrospinal fluid from rhesus macaques (Macaca mulatta). Comparative Medicine 66(4), 349–352.