Nonhuman Primate

A new group housing approach for non-human primate metabolism studies

Understanding the absorption, distribution, metabolism and excretion (ADME) of candidate drugs in preclinical species is an integral part of the safety and efficacy evaluation in drug development. For this purpose, the housing of single animals in metabolism cages has historically...

Year Published: 2021Topics: Biological Sampling & Physiological Measurement, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Stow, R., Kendrick, J., Ibbotson, N. et al. 2021. A new group housing approach for non-human primate metabolism studies. Journal of Pharmacological and Toxicological Methods 107, 106947.

Reducing suffering in experimental autoimmune encephalomyelitis (EAE)

This report is based on discussions and submissions from an expert working group consisting of veterinarians, animal care staff and scientists with expert knowledge relevant to the field. It aims to facilitate the implementation of the Three Rs (replacement, reduction...

Year Published: 2013Topics: Disease/Experimental ModelAnimal Type: Dog, Guinea Pig, Hamster, Macaque, Marmoset, Mouse, Nonhuman Primate, Rabbit, Rat, Rodent, Sheep

Citation: Wolfensohn, S., Hawkins, P., Lilley, E. et al. 2013. Reducing suffering in experimental autoimmune encephalomyelitis (EAE). Journal of Pharmacological and Toxicological Methods 67(3), 169-176.

Individually customisable non-invasive head immobilisation system for non-human primates with an option for voluntary engagement

Background: Head immobilisation is often necessary for neuroscientific procedures. A number of Non-invasive Head Immobilisation Systems (NHIS) for monkeys are available, but the need remains for a feasible integrated system combining a broad range of essential features. New Method: We...

Year Published: 2016Topics: External Bodily EquipmentAnimal Type: Macaque, Nonhuman Primate

Citation: Slater, H., Milne, A. E., Wilson, B. et al. 2016. Individually customisable non-invasive head immobilisation system for non-human primates with an option for voluntary engagement. Journal of Neuroscience Methods 269, 46-60.

Protective cranial implant caps for macaques

Background: Neuroscience studies with macaque monkeys may require cranial implants to stabilize the head or gain access to the brain for scientific purposes. Wound management that promotes healing after the cranial implant surgery in non-human primates can be difficult as...

Year Published: 2021Topics: External Bodily EquipmentAnimal Type: Macaque, Nonhuman Primate

Citation: Perry, B. A. L., Mason, S., Nacef, J. et al. 2021. Protective cranial implant caps for macaques. Journal of Neuroscience Methods 348, 108992.

Marmosets: Welfare, ethical use, and IACUC/regulatory considerations

Use of marmosets in biomedical research has increased dramatically in recent years due, in large part, to their suitability for transgenic applications and utility as models for neuroscience investigations. This increased use includes the establishment of new colonies and involvement...

Year Published: 2020Topics: Regulations & Ethical ReviewAnimal Type: Marmoset, Nonhuman Primate

Citation: Colman, R. J., Capuano, 3rd, S., Bakker, J. et al. 2021. Marmosets: Welfare, ethical use, and IACUC/regulatory considerations. ILAR Journal 61(2-3), 167-178.

Current topics in marmoset anesthesia and analgesia

Anesthetic and analgesics are essential components of both clinical and research procedures completed in marmosets. A review of current anesthetic and analgesic regimens for marmosets has been complied to provide a concise reference for veterinarians and investigator teams. Published dose...

Year Published: 2020Topics: Anesthesia & SedationAnimal Type: Marmoset, Nonhuman Primate

Citation: Goodroe, A., Fitz, C., Bakker, J. 2020. Current topics in marmoset anesthesia and analgesia. ILAR Journal 61(2-3), 218-229.

The importance of complementary collaboration of researchers, veterinarians, and husbandry staff in the successful training of marmoset behavioral assays

Interest in marmosets as research models has seen exponential growth over the last decade, especially given that the research community is eager to improve on gaps with historical animal models for behavioral and cognitive disorders. The spectrum of human disease...

Year Published: 2020Topics: Animal Training, Husbandry & ManagementAnimal Type: Marmoset, Nonhuman Primate

Citation: Murai, T., Sukoff Rizzo, S. J. 2020. The importance of complementary collaboration of researchers, veterinarians, and husbandry staff in the successful training of marmoset behavioral assays. ILAR Journal 61(2-3), 230-247.

Swimming and diving as social play in juvenile rhesus macaques (Macaca mulatta)

Although play is ubiquitous throughout the animal kingdom, and in primates especially, the ultimate explanations and proximate mechanisms of play are not well understood. Previous research proposes that primate play may be important for the development of cognitive skills including...

Year Published: 2021Topics: Environmental Enrichment, Natural BehaviorAnimal Type: Macaque, Nonhuman Primate

Citation: Arre, A. M., Horschler, D. J. 2021. Swimming and diving as social play in juvenile rhesus macaques (Macaca mulatta). Behaviour 158(6), 529-546.

Influence of female coalitionary aggressive behavior on the success of male introductions to female groups of rhesus macaques (Macaca Mulatta)

Migration patterns of wild rhesus macaque males are often mimicked in captivity by introducing unfamiliar males to female groups every few years. This strategy prevents inbreeding and has been shown to encourage group stability once males are fully integrated. The...

Year Published: 2021Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Bailey, K. L., Bloomsmith, M. A., Michopoulos, V. et al. 2021. Influence of female coalitionary aggressive behavior on the success of male introductions to female groups of rhesus macaques (Macaca Mulatta). Applied Animal Behaviour Science 237, 105293.

Retrospective analysis of the effectiveness and reversibility of long-acting contraception Etonogestrel (Implanon®) in common marmosets (Callithrix jacchus)

Contraception is an important population control method for the colony management of primates housed in captivity. Etonogestrel (ENG) implants (i.e., Implanon®) are a widely used progestin-based contraceptive in common marmosets (Callithrix jacchus) with the theoretical advantages of being reversible and...

Year Published: 2021Topics: ReproductionAnimal Type: Marmoset, Nonhuman Primate

Citation: Roubos, S., Louwerse, A. L., Langermans, J. A. M. et al. 2021. Retrospective analysis of the effectiveness and reversibility of long-acting contraception Etonogestrel (Implanon®) in common marmosets (Callithrix jacchus). Animals 11(4), 963.