Mouse

Evaluation of the effects of space allowance on measures of animal welfare in laboratory mice

We studied how space allowance affects measures of animal welfare in mice by systematically varying group size and cage type across three levels each in both males and females of two strains of mice (C57BL/6ByJ and BALB/cByJ; n = 216...

Year Published: 2018Topics: Housing, Social Housing & Companionship, Stocking DensityAnimal Type: Mouse, Rodent

Citation: Bailoo, J. D., Murphy, E., Varholick, J. A. et al. 2018. Evaluation of the effects of space allowance on measures of animal welfare in laboratory mice. Scientific Reports 8, 713.

Effect of light colour temperature and intensity on the behaviour of male C57CL/6J mice

Light is an important environmental factor affecting laboratory animals' well-being but still there is a range of light parameters in animal research facilities that need further study. Behavioural testing was conducted to study the impact of different conditions of light...

Year Published: 2016Topics: Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Kapogiannatou, A., Paronis, E., Paschidis, K. et al. 2016. Effect of light colour temperature and intensity on the behaviour of male C57CL/6J mice. Applied Animal Behaviour Science 184, 135-140.

He’s getting under my skin! Comparing the sensitivity and specificity of dermal vs subcuticular lesions as a measure of aggression in mice

Aggression is the leading cause of death in young laboratory mice, representing a major welfare issue. Many of the experimental measures used in traditional aggression research, especially those focusing on territorial aggression (e.g., resident/intruder) are poorly suited to examining dominance...

Year Published: 2016Topics: Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Gaskill, B. N., Stottler, A., Pritchett-Corning, K. R. et al. 2016. He's getting under my skin! Comparing the sensitivity and specificity of dermal vs subcuticular lesions as a measure of aggression in mice. Applied Animal Behaviour Science 183, 77-85.

Personality predicts the responses to environmental enrichment at the group but not within-groups in stereotypic African striped mice, Rhabdomys dilectus

Environmental enrichment is used to enhance the well-being of captive animals and to prevent or reduce stereotypic and other abnormal behaviours. However, environmental enrichment does not always succeed in its intended purpose. We investigated whether personality (i.e. consistent individual variation...

Year Published: 2016Topics: Abnormal/Problematic Behavior, Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Joshi, S., Pillay, N. 2016. Personality predicts the responses to environmental enrichment at the group but not within-groups in stereotypic African striped mice, Rhabdomys dilectus. Applied Animal Behaviour Science 182, 44-52.

Mice aversion to sevoflurane, isoflurane and carbon dioxide using an approach-avoidance task

Euthanasia of laboratory animals is one of the main concerns for animal welfare, especially the use of carbon dioxide (CO2) which has been described to induce aversive-like behaviours. In order to refine mass euthanasia in rodents, this study aims to...

Year Published: 2017Topics: EuthanasiaAnimal Type: Mouse, Rodent

Citation: Guedes, S. R., Valentim, A. M., Antunes, L. M. 2017. Mice aversion to sevoflurane, isoflurane and carbon dioxide using an approach-avoidance task. Applied Animal Behaviour Science 189, 91-97.

The impact of bedding volumes on laboratory mice

Environmental refinement is considered to be an improvement in housing conditions for laboratory animals. Previous preference tests showed that female BALB/c and C57BL/6 mice prefer deeper bedding in comparison to shallow bedding (Freymann et al., 2015). In order to give...

Year Published: 2017Topics: Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Freymann, J., Tsai, P.-P., Stelzer, H. et al. 2017. The impact of bedding volumes on laboratory mice. Applied Animal Behaviour Science 186, 72-79.

Buprenorphine via drinking water and combined oral-injection protocols for pain relief in mice

Buprenorphine is the opioid analgesic most commonly used in laboratory mice. However, to maintain therapeutically effective serum levels, repeated injections are required. To overcome negative aspects of restraint and injection, oral self-administration is a promising alternative but has been criticized...

Year Published: 2016Topics: AnalgesiaAnimal Type: Mouse, Rodent

Citation: Sauer, M., Fleischmann, T., Lipiski, M. et al. 2016. Buprenorphine via drinking water and combined oral-injection protocols for pain relief in mice. Applied Animal Behaviour Science 185, 103-112.

Tramadol:Paracetamol in drinking water for treatment of post-surgical pain in laboratory mice

In the search for stress-free analgesia administration for laboratory mice suffering pain, oral delivery of Tramadol:Paracetamol (T:P) shows great promise. Here, we monitored the analgesic efficacy and side effects of a T:P combination administered solely in the drinking water of...

Year Published: 2018Topics: AnalgesiaAnimal Type: Mouse, Rodent

Citation: Jirkof, P., Arras, M., Cesarovic, N. 2018. Tramadol:Paracetamol in drinking water for treatment of post-surgical pain in laboratory mice. Applied Animal Behaviour Science 198, 95-100.

The effects of mining machinery noise of different frequencies on the behaviour, faecal corticosterone and tissue morphology of wild mice (Mus musculus)

Mining noise has a wide variety of frequency spectra and is a potential source of stress for wildlife. We evaluated the effects of mining machinery noise on behaviour and associated physiological parameters at two isoenergetic frequency ranges: high (>2kHz) and...

Year Published: 2017Topics: Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Mancera, K. F., Lisle, A. Allavena, R. et al. 2017. The effects of mining machinery noise of different frequencies on the behaviour, faecal corticosterone and tissue morphology of wild mice (Mus musculus). Applied Animal Behaviour Science 197, 81-89.

Ethological approach to social isolation effects in behavioral studies of laboratory rodents

The aim of the present review is to discuss how housing conditions affect behavioral performance in laboratory rodents from an ethological view. Commonly used laboratory rodents such as rats and mice, are originally captured animals that largely retain species-typical natural...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Mouse, Rat, Rodent

Citation: Arakawa, H. 2018. Ethological approach to social isolation effects in behavioral studies of laboratory rodents. Behavioural Brain Research 341, 98-108.