Macaque

Modular, cement-free, customized headpost and connector-chamber implants for macaques

Background: Neurophysiological studies with awake macaques typically require chronic cranial implants. Headpost and connector-chamber implants are used to allow head stabilization and to house connectors of chronically implanted electrodes, respectively. New method: We present long-lasting, modular, cement-free headpost implants made...

Year Published: 2023Topics: External Bodily EquipmentAnimal Type: Macaque, Nonhuman Primate

Citation: Psarou, E., Vezoli, J., Schölvinck, M. L. et al. 2023. Modular, cement-free, customized headpost and connector-chamber implants for macaques. Journal of Neuroscience Methods 393, 109899.

The impact of housing on birth outcomes in breeding macaque groups across multiple research centers

Demand for nonhuman primates in research has increased over the past several years, while nonhuman primate supply remains a challenge in the United States. Global nonhuman primate supply issues make it increasingly important to maximize domestic colony production. To explore...

Year Published: 2023Topics: Housing, Rearing & WeaningAnimal Type: Macaque, Nonhuman Primate

Citation: Haertel, A. J., Beisner, B. A., Buehler, M. S. et al. 2023. The impact of housing on birth outcomes in breeding macaque groups across multiple research centers. American Journal of Primatology 85(11), e23554.

Less invasive, simultaneous, and continuous measurements of locomotor activity and body temperature using the nano tag® small accelerometer device in cynomolgus monkeys

Locomotor activity and body temperature evaluations of cynomolgus monkeys are useful to understand the effects of drugs on the central nervous system. Here, we describe a simple, inexpensive, and less invasive evaluation method using the nano tag® (KISSEI COMTEC Co.,...

Year Published: 2022Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Kishida, T., Motokawa, Y., Yokoi, R. et al. 2022. Less invasive, simultaneous, and continuous measurements of locomotor activity and body temperature using the nano tag® small accelerometer device in cynomolgus monkeys. Journal of Pharmacological and Toxicological Methods 118, 107224.

Blood microsampling in cynomolgus monkey and evaluation of plasma PK parameters in comparison to conventional sampling

Microsampling, a reduced volume sampling method, has successfully gained attention at the International Conference on Harmonization (ICH) level and established benefits support its use in Toxicokinetic (TK) studies. These improved sampling techniques are less invasive and in large animal species...

Year Published: 2023Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Bertani, S., Donadi, A., Franchi, J. et al. 2023. Blood microsampling in cynomolgus monkey and evaluation of plasma PK parameters in comparison to conventional sampling. Journal of Pharmacological and Toxicological Methods 123, 107298.

Nonhuman primate enrichment evaluation program

Noting that it is typical for enrichment devices to be approved by a committee and understanding that this is paramount for animal safety, we began to think outside the box and seek additional ways to approve enrichment devices for the...

Year Published: 2023Topics: Environmental EnrichmentAnimal Type: Macaque, Nonhuman Primate

Citation: Deugan, C. R., Gross, A. A. 2023. Nonhuman primate enrichment evaluation program. Laboratory Animal Science Professional 11(2) (March/April), 46-49.

Thirty years of telemetry-based data acquisition for cardiovascular drug safety evaluation: Applications and optimization

Conducting safety evaluations of new drugs using conscious animals has been a specialty of our working group for thirty years. In this article, we review the various technical challenges and solutions dealt with over the years to improve both the...

Year Published: 2023Topics: Biological Sampling & Physiological Measurement, External Bodily EquipmentAnimal Type: Dog, Guinea Pig, Macaque, Mouse, Nonhuman Primate, Pig, Rat, Rodent

Citation: Alizadeh, E. A., Graf, K., Schiwon, J. et al. 2023. Thirty years of telemetry-based data acquisition for cardiovascular drug safety evaluation: Applications and optimization. Journal of Pharmacological and Toxicological Methods 122, 107279.

The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals (9th ed.)

The latest edition of the seminal reference on the care and management of laboratory and research animals. The newly revised ninth edition of The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals delivers an up-to-date...

Year Published: 2024Topics: Animal Training, Environmental Enrichment, Euthanasia, Housing, Husbandry & Management, Natural Behavior, Relocation & Transport, Welfare AssessmentAnimal Type: Amphibian, Bird, Capuchin, Cat, Cattle, Cephalopod, Crustacean, Dog, Equine, Ferret, Finch, Fish, Fowl, Frog & Toad, Gerbil, Goat, Guinea Pig, Hamster, Invertebrate, Lizard, Macaque, Marmoset, Mole Rat, Mouse, Nonhuman Primate, Other Animal, Other Bird, Other Fish, Other Nonhuman Primate, Other Rodent, Pig, Rabbit, Rat, Reptile, Rodent, Sheep, Snake, Tree Shrew, Turtle & Tortoise, Vervet (African Green Monkey), Zebrafish

Citation: Golledge, H., Richardson, C. (Eds.) 2024. The UFAW Handbook on the Care and Management of Laboratory and Other Research Animals (9th ed.). Wiley-Blackwell. 1040 p.

A fine-scale and minimally invasive marking method for use with conventional tungsten microelectrodes

In neurophysiology, achieving precise correlation between physiological responses and anatomic structures is a significant challenge. Therefore, the accuracy of the electrode marking method is crucial. In this study, we describe a tungsten-deposition method, in which tungsten oxide is generated by...

Year Published: 2023Topics: Imaging & Electrophysiological RecordingAnimal Type: Macaque, Mouse, Nonhuman Primate, Rodent

Citation: Oikawa, T., Nomura, K., Hara, T. et al. 2023. A fine-scale and minimally invasive marking method for use with conventional tungsten microelectrodes. eNeuro 10(9), ENEURO.0141-23.2023.

Mechanisms underlying cognitive bias in nonhuman primates

Recent research in nonhuman animals highlights the exciting possibility that performance on cognitive bias tasks might indirectly measure an individual's subjective, affective state. Subjects first learn to perform a conditional discrimination task with two differentially reinforced responses, and then intermediate,...

Year Published: 2017Topics: Welfare AssessmentAnimal Type: Capuchin, Macaque, Nonhuman Primate

Citation: Perdue, B. 2017. Mechanisms underlying cognitive bias in nonhuman primates. Animal Behavior and Cognition 4(1), 105–118.

A comparison of oocyte yield between ultrasound-guided and laparoscopic oocyte retrieval in rhesus macaques

Obtaining quality oocytes is a prerequisite for ART-based studies. Here we describe a method for transabdominal ultrasound-guided (US) oocyte retrieval in rhesus macaques (Macaca mullata) and compare it to the standard surgical approach using laparoscopy (LAP). We analyzed oocyte yield...

Year Published: 2023Topics: Reproduction, Surgery & Post-OpAnimal Type: Macaque, Nonhuman Primate

Citation: Piekarski, N., Hobbs, T. R., Jacob, D. et al. 2023. A comparison of oocyte yield between ultrasound-guided and laparoscopic oocyte retrieval in rhesus macaques. Animals 13(19), 3017.