Reporting the implementation of the three Rs in European primate and mouse research papers: Are we making progress? Alternatives to Laboratory Animals 38(6), 495-517

It is now more than 20 years since both Council of Europe Convention ETS123 and EU Directive 86/609/EEC were introduced, to promote the implementation of the Three Rs in animal experimentation and to provide guidance on animal housing and care....

Year Published: 2010Topics: Regulations & Ethical ReviewAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Mouse, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Rodent, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Taylor K. 2010. Reporting the implementation of the three Rs in European primate and mouse research papers: Are we making progress? Alternatives to Laboratory Animals 38(6), 495-517.

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The COST Manual of Laboratory Animal Care and Use: Refinement, Reduction, and Research (1st Ed)

COST Action B-24 established four working groups to research and discuss issues relevant to laboratory animal science. These included the housing of animals, environmental needs, refinement of procedures, genetically modified animals, and cost-benefit analysis. Based on the groups' findings, The...

Year Published: 2010Topics: Environmental Enrichment, Euthanasia, Handling, Housing, Regulations & Ethical Review, Surgery & Post-OpAnimal Type: Mouse, Rabbit, Rat, Rodent

Citation: Howard, B., Nevalainen, T., Perretta, G. (ed). 2010. The COST Manual of Laboratory Animal Care and Use: Refinement, Reduction, and Research (1st Ed). CRC Press, Boca Raton, FL.

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Weighing the costs and benefits of animal experiments

Most regulations governing animal experimentation require that the harms expected to be incurred by animal subjects should be balanced against the likely benefits of the project. Too often, however, expected human benefits are based on unrealistic assumptions. To critically assess...

Year Published: 2011Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Knight, A. 2011. Weighing the costs and benefits of animal experiments. Alternatives to Animal Experimentation [ALTEX] Proceedings of WC8, 289-294.

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The Animal Welfare Act: From enactment to enforcement

Originally enacted in 1966, the Laboratory Animal Welfare Act has been amended several times and renamed the Animal Welfare Act. Responsibility for administering the Animal Welfare Act was delegated within the United States Department of Agriculture to the Administrator of...

Year Published: 2012Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Cardon, A. D., Bailey, M. R., Bennett, B. T. 2012. The Animal Welfare Act: From enactment to enforcement. JAALAS 51(3), 301-305.

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ICLAS Working Group on Harmonization: International guidance concerning the production care and use of genetically-altered animals

Replacement, Reduction and Refinement, the Three Rs of Russell & Burch, are accepted worldwide as fundamental to the ethics of animal experimentation. The production, care and use of genetically-altered animals can pose particular challenges to the implementation of the Three...

Year Published: 2013Topics: Regulations & Ethical ReviewAnimal Type: All/General

Citation: Rose, M., Everitt, J., Hedrich, H. et al. 2013. ICLAS Working Group on Harmonization: International guidance concerning the production care and use of genetically-altered animals. Laboratory Animals 47(3), 146-192.

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Clinical Laboratory Animal Medicine: An Introduction (4th Ed)

Clinical Laboratory Animal Medicine: An Introduction, Fourth Edition offers a user-friendly guide to the unique anatomy and physiology, care, common diseases, and treatment of small mammals and nonhuman primates. Carefully designed for ease of use, the book includes tip boxes,...

Year Published: 2013Topics: Environmental Enrichment, Housing, Husbandry & Management, Regulations & Ethical Review, Welfare AssessmentAnimal Type: Baboon, Capuchin, Chimpanzee, Chinchilla, Ferret, Gerbil, Guinea Pig, Hamster, Lemur, Macaque, Marmoset, Mouse, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Rabbit, Rat, Rodent, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Hrapkiewicz, K., Colby, L. A., Denison, P. 2013. Clinical Laboratory Animal Medicine: An Introduction (4th Ed). Wiley-Blackwell, Ames, IA.

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