Imaging & Electrophysiological Recording

Minimally invasive electrocorticography (ECoG) recording in common marmosets

Background: Electrocorticography (ECoG) provides a valuable compromise between spatial and temporal resolution for recording brain activity with excellent signal quality, crucial for presurgical epilepsy mapping and advancing neuroscience, including brain-machine interface development. ECoG is particularly effective in the common marmoset...

Year Published: 2025Topics: Imaging & Electrophysiological RecordingAnimal Type: Marmoset, Nonhuman Primate

Citation: Spadacenta, S., Dicke, P. W., Thier, P. 2025. Minimally invasive electrocorticography (ECoG) recording in common marmosets. Journal of Neuroscience Methods 417, 110409.

Development of a non-invasive novel individual marmoset holder for evaluation by awake functional magnetic resonance brain imaging

Background: Although functional MRI (fMRI) in awake marmosets (Callithrix jacchus) is fascinating for functional brain mapping and evaluation of brain disease models, it is difficult to launch awake fMRI on scanners with bore sizes of less than 16 cm. A universal...

Year Published: 2025Topics: Imaging & Electrophysiological RecordingAnimal Type: Marmoset, Nonhuman Primate

Citation: Seki, F., Yurimoto, T., Kamioka, M. et al. 2025. Development of a non-invasive novel individual marmoset holder for evaluation by awake functional magnetic resonance brain imaging. Journal of Neuroscience Methods 417, 110390.

Thermal imaging in biomedical research: a non-invasive technology for animal models (2025)

Thermal imaging has been used in animal models to non-invasively detect surface temperature changes after several pathologic and surgical processes. Infrared thermography (IRT) identifies increases or decreases in radiated heat according to blood circulation and microcirculation. The present review aims...

Year Published: 2025Topics: Imaging & Electrophysiological RecordingAnimal Type: All/General

Citation: Verduzco-Mendoza, A., Olmos-Hernández, A., Bueno-Nava, A. et al. 2025. Thermal imaging in biomedical research: A non-invasive technology for animal models. Frontiers in Veterinary Science 12.

Non-invasive scalp recording of electroencephalograms and evoked potentials in unanesthetized horses using a 12-channel active electrode array

Despite the long history of the horse-human bond, our understanding of the brain and mind of horses remains limited due to the lack of methods to investigate their brain functions. This study introduces a novel methodology for completely non-invasive, multi-channel...

Year Published: 2024Topics: Imaging & Electrophysiological RecordingAnimal Type: Equine

Citation: Itoh, K., Kikumura, N., Maeda, T. et al. 2024. Non-invasive scalp recording of electroencephalograms and evoked potentials in unanesthetized horses using a 12-channel active electrode array. Frontiers in Veterinary Science 11.

Ultrasound to ultrasee—The use of ultrasound to determine pregnancy in mice

Several MRC Laboratory of Molecular Biology (LMB) groups require early-stage mouse embryos for their scientific research programmes. Traditionally, Animal Technicians have relied on visual checks or palpation of the abdomen to determine pregnancy in mice. In 2017 an ultrasound machine...

Year Published: 2024Topics: Imaging & Electrophysiological Recording, ReproductionAnimal Type: Mouse, Rodent

Citation: Karam, C., Kemp, K. 2024. Ultrasound to ultrasee—The use of ultrasound to determine pregnancy in mice. Animal Technology and Welfare 23(2), 121–127.

Non-invasive electroencephalography in awake cats: Feasibility and application to sensory processing in chronic pain

Background: Feline osteoarthritis (OA) leads to chronic pain and somatosensory sensitisation. In humans, sensory exposure can modulate chronic pain. Recently, electroencephalography (EEG) revealed a specific brain signature to human OA. However, EEG pain characterisation or its modulation does not exist...

Year Published: 2024Topics: Imaging & Electrophysiological RecordingAnimal Type: Cat

Citation: Delsart, A., Castel, A., Dumas, G. et al. 2024. Non-invasive electroencephalography in awake cats: Feasibility and application to sensory processing in chronic pain. Journal of Neuroscience Methods 411, 110254.

Novel development of magnetic resonance imaging to quantify the structural anatomic growth of diverse organs in adult and mutant zebrafish

Zebrafish (Danio rerio) is a widely used vertebrate animal for modeling genetic diseases by targeted editing strategies followed by gross phenotypic and biomarker characterization. While larval transparency permits microscopic detection of anatomical defects, histological adult screening for organ-level defects remains...

Year Published: 2024Topics: Imaging & Electrophysiological RecordingAnimal Type: Fish, Zebrafish

Citation: Sharma, S., Magnitsky, S., Reesey, E. et al. 2024. Novel development of magnetic resonance imaging to quantify the structural anatomic growth of diverse organs in adult and mutant zebrafish. Zebrafish 21(1), 28–38.

What N Is N-ough for MRI-based animal neuroimaging? eNeuro 11(3), ENEURO

Fueled by the recent and controversial brain-wide association studies in humans, the animal neuroimaging community has also begun questioning whether using larger sample sizes is necessary for ethical and effective scientific progress. In this opinion piece, we illustrate two opposing...

Year Published: 2024Topics: Imaging & Electrophysiological RecordingAnimal Type: All/General, Mouse, Rat, Rodent

Citation: Grandjean, J., Lake, E. M. R., Pagani, M. et al. 2024. What N Is N-ough for MRI-based animal neuroimaging? eNeuro 11(3), ENEURO.0531-23.2024.

The arterial blood sampling associated with PET imaging studies can lead to post-scan complications in Göttingen minipigs

When disease progression or treatment effects are investigated, pigs are frequently used for imaging studies. We recently showed that prolonged anesthesia with intensive blood sampling and road transportation affect internal organs in non-recovery imaging studies in domestic pigs. In the...

Year Published: 2024Topics: Biological Sampling & Physiological Measurement, Imaging & Electrophysiological RecordingAnimal Type: Pig

Citation: Alstrup, A. K. O., Thea Pinholt Lillethorup, Landau, A. M. et al. 2024. The arterial blood sampling associated with PET imaging studies can lead to post-scan complications in Göttingen minipigs. Scandinavian Journal of Laboratory Animal Science 50, 6–12.

Improving behavior monitoring of free-moving dairy cows using noninvasive wireless EEG approach and digital signal processing techniques

Electroencephalography (EEG) is the most common method to access brain information. Techniques to monitor and extract brain signal characteristics in farm animals are not as developed as those for humans and laboratory animals. The objective of this study was to...

Year Published: 2023Topics: Imaging & Electrophysiological RecordingAnimal Type: Cattle

Citation: Silva, A. C. de S., Arce, A. I. C., Arteaga, H. et al. 2023. Improving behavior monitoring of free-moving dairy cows using noninvasive wireless EEG approach and digital signal processing techniques. Applied Sciences 13(19), 10722.