Disease/Experimental Model

Chimpanzees in AIDS research: A biomedical and bioethical perspective

The present article represents a consensus view of the appropriate utilization of chimpanzees in AIDS research arrived at as a result of a meeting of a group of scientists involved in AIDS research with chimpanzees and bioethicists. The paper considers...

Year Published: 1994Topics: Disease/Experimental Model, Relocation & Transport, Social Housing & CompanionshipAnimal Type: Chimpanzee, Nonhuman Primate

Citation: van Akker, R., Balls, M., Eichberg, J. W. et al. 1994. Chimpanzees in AIDS research: A biomedical and bioethical perspective. Journal of Medical Primatology 23, 49-51.

The Boyd Group of papers on: The use of non-human primates in research and testing – Pager 1: Background information on the use of non-human primates

Number of non-human primates used in scientific procedures in Britain in 2000: New World monkeys [marmosets, tamarins] 1060; Old World monkeys [macaques] 1891 [p.100].

Year Published: 2003Topics: Disease/Experimental ModelAnimal Type: Nonhuman Primate, Salamander

Citation: Smith, J. A., Boyd, K. M. e. 2003. The Boyd Group of papers on: The use of non-human primates in research and testing - Pager 1: Background information on the use of non-human primates. Animal Technology and Welfare 2, 99-103.

The poor contribution of chimpanzee experiments to biomedical progress

Biomedical research on captive chimpanzees incurs substantial nonhuman animal welfare, ethical, and financial costs that advocates claim result in substantial advancements in biomedical knowledge. However, demonstrating minimal contribution toward the advancement of biomedical knowledge generally, subsequent papers did not cite...

Year Published: 2007Topics: Disease/Experimental Model, Regulations & Ethical ReviewAnimal Type: Chimpanzee, Nonhuman Primate

Citation: Knight, A. 2007. The poor contribution of chimpanzee experiments to biomedical progress. Journal of Applied Animal Welfare Science 10(4), 281-308.

Report of the 2006 RSPCA/UFAW Rodent Welfare Group meeting

The RSPCA/UFAW Rodent Welfare Group holds a one-day meeting every autumn to discuss current welfare research and to exchange views on rodent welfare issues. A key aim of the group is to encourage people to think about the lifetime experience...

Year Published: 2008Topics: Disease/Experimental Model, Euthanasia, Housing, Husbandry & ManagementAnimal Type: Mouse, Rat, Rodent

Citation: Reed, B., Hawkins, P., Latham, N. et al. 2008. Report of the 2006 RSPCA/UFAW Rodent Welfare Group meeting. Lab Animal 37(5), 216-222.

Biomedical applications of sheep models: from asthma to vaccines

Although rodent models are very popular for scientific studies, it is becoming more evident that large animal models can provide unique opportunities for biomedical research. Sheep are docile in nature and large in size, which facilitates surgical manipulation, and their...

Year Published: 2008Topics: Disease/Experimental ModelAnimal Type: Sheep

Citation: Scheerlinck, J. P. Y., Snibson, K. J., Bowles, V. M. et al. 2008. Biomedical applications of sheep models: from asthma to vaccines. Trends in Biotechnology 26, 259-266.

Cage enrichment with paper tissue, but not plastic tunnels, increases variability in mouse model of asthma

Environmental enrichment, besides having a great impact on animal welfare, can also be a potential variable in experimental research. Thus, we investigated whether enrichment of cages with paper tissues or plastic tunnels affects scientific outcome in the well-described mouse model...

Year Published: 2011Topics: Disease/Experimental Model, Environmental Enrichment, HousingAnimal Type: Mouse, Rodent

Citation: Pasalic, I., Bosnjak, B., Ivetic Tkalcevic, V. et al. 2011. Cage enrichment with paper tissue, but not plastic tunnels, increases variability in mouse model of asthma. Laboratory Animals 45(2), 121-123.

The beneficial effects of enrichment on diabetic mice

In the last issue of The Enrichment Record, Emily Patterson-Kane and I reported on the work (Cao, Liu et al.) in which investigators demonstrated that even short-term exposure to environmental enrichment (EE) improved resistance to cancer in a number of...

Year Published: 2011Topics: Disease/Experimental Model, Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Lett, G. S. 2011. The beneficial effects of enrichment on diabetic mice. Enrichment Record 6, 5.

Effect of light intensity as determined by cage rack position on tumor growth in a mouse model of melanoma

Within the typical laboratory animal housing facility, animals may be exposed to varying intensities of light as a result of cage type, cage position, light source, and other factors. While evidence exists that light contamination during the dark phase of...

Year Published: 2013Topics: Disease/Experimental Model, Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Suckow, M. A., Wilhite, S., Wolter, W. R. et al. 2013. Effect of light intensity as determined by cage rack position on tumor growth in a mouse model of melanoma. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 670 (Abstract #P178).

Benefits of an enhanced enrichment program for a canine research colony

The overall benefits of an enrichment and exercise program for research canines has been well documented and is a required element, by the United States Department of Agriculture (USDA), of any institution's Animal Care and Use Program. However, some research...

Year Published: 2013Topics: Disease/Experimental Model, Environmental Enrichment, Housing, Relocation & TransportAnimal Type: Dog

Citation: Sposato, M. 2013. Benefits of an enhanced enrichment program for a canine research colony. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 669 (Abstract #P176).

Refinements in laboratory cat management: While the humans are away, the cats will play! Laboratory Animal Science Professional 1(4) (December), 32-35

Cats can be successfully housed in groups when given enough space in addition to sufficient feeding, elimination, and resting areas. Cats at the University of Rochester are utilized in vision research, and have titanium cranium implants to stabilize their heads...

Year Published: 2013Topics: Disease/Experimental Model, Social Housing & CompanionshipAnimal Type: Cat

Citation: Rehrig, A., DeMagistris, M., Callan, C. 2013. Refinements in laboratory cat management: While the humans are away, the cats will play! Laboratory Animal Science Professional 1(4) (December), 32-35.