Biological Sampling & Physiological Measurement

Refining the blood collection procedure for macaques

Training protocol is described. These findings lead to the conclusion that training nonhuman primates to cooperate during venipuncture in their familiar home environment offers a methodological refinement by eliminating significant cortisol responses.

Year Published: 1996Topics: Animal Training, Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Reinhardt, V. 1996. Refining the blood collection procedure for macaques. Lab Animal 25(1), 32-35.

Training nonhuman primates to cooperate during handling procedures: A review

Twenty-six reports provide detailed information of how primates can be trained to voluntarily cooperate - rather than resist - during blood collection, injection, topical drug application, blood pressure measurement, urine collection, and capture.

Year Published: 1997Topics: Animal Training, Biological Sampling & Physiological Measurement, Cannulation, Catheterization, & Intubation, Human-Animal Interaction, RestraintAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Reinhardt, V. 1997. Training nonhuman primates to cooperate during handling procedures: A review. Animal Technology 48, 55-73.

Training and remote monitoring of cardiovascular parameters in non-human primates

The use of "pre-invasive" implantable radio telemetry has revolutionized the collection of physiological data under stress-free conditions. It is now possible to measure accurately 'normal' baseline data of haemodynamic and electrical parameters in conscious and unrestrained monkeys. The use of...

Year Published: 1997Topics: Animal Training, Biological Sampling & Physiological Measurement, RestraintAnimal Type: Macaque, Marmoset, Nonhuman Primate

Citation: Schnell, C. R., Gerber, P. 1997. Training and remote monitoring of cardiovascular parameters in non-human primates. Primate Report 49, 61-70.

Behavior and salivary cortisol in gorillas housed in an all male group

Group-housed male gorillas were trained to voluntarily chew on the cotton plugs then return them to the caretaker ... Further analysis of these data may provide a better understanding of how the gorillas are perceiving and adapting to their physical...

Year Published: 1998Topics: Biological Sampling & Physiological MeasurementAnimal Type: Nonhuman Primate, Other Nonhuman Primate

Citation: Bettinger, T., Kuhar, C., Sironen, A. et al. 1998. Behavior and salivary cortisol in gorillas housed in an all male group. American Zoo and Aquarium Association (AZA) Annual Conference Proceedings, 242-246.

Tomorrow’s animal management today – semen collection in gorillas using behavioral training

Three male gorillas were trained to provide semen samples and allow a physical examination. Training was based on a standard training method - food rewards and verbal praise.

Year Published: 1998Topics: Animal Training, Biological Sampling & Physiological MeasurementAnimal Type: Nonhuman Primate, Other Nonhuman Primate

Citation: Brown, C. S. 1998. Tomorrow's animal management today - semen collection in gorillas using behavioral training. American Zoo and Aquarium Association (AZA) Regional Conference Proceedings, 416-418.

Collecting blood of macaques: An often overlooked variable in biomedical research

The findings of this survey suggest that many investigators do not recognize that the traditional manner of collecting blood can introduce uncontrolled stress variables into research findings, leading to increased data variability and therefore increasing the number of experimental animals...

Year Published: 1999Topics: Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Reinhardt, V. 1999. Collecting blood of macaques: An often overlooked variable in biomedical research. Laboratory Primate Newsletter 38(4), 4-5.

A few new developments in primate housing and husbandry

A major focus of this paper is an examination of the complementary role that behavioral management strategies play in the establishment and enhancement of well-defined nonhuman primate research resources. .... Additionally, I will discuss the use of positive reinforcement training...

Year Published: 2000Topics: Animal Training, Biological Sampling & Physiological MeasurementAnimal Type: Chimpanzee, Macaque, Nonhuman Primate

Citation: Schapiro, S. J. 2000. A few new developments in primate housing and husbandry. Scandinavian Journal of Laboratory Animal Science 27(2), 103-110.

Blood collection procedure of laboratory primates: A neglected variable in biomedical research

A survey of 75 biomedical articles dealing with stress-dependent blood parameters in caged primates revealed that the conditions under which blood collection occurred were in most cases [72%] described either not at all or so haphazardly that it would be...

Year Published: 2000Topics: Biological Sampling & Physiological Measurement, HandlingAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Reinhardt, V., Reinhardt, A. 2000. Blood collection procedure of laboratory primates: A neglected variable in biomedical research. Journal of Applied Animal Welfare Science 3(4), 321-333.

Training pair-housed rhesus males to cooperate during blood collection

In many laboratory studies, venipuncture (blood collection) is a routine activity. Some animal care managers assume that blood collection requires single-housing and squeezing (and stressing) the primate subjects. Not true!Here, we show a simple training procedure that is based on...

Year Published: 2001Topics: Animal Training, Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Reinhardt, V. 2001. Training pair-housed rhesus males to cooperate during blood collection. Primate Enrichment Network (PEN), Item #: A107.

Training macaques to voluntarily co-operate during two common procedures: Blood collection and capture of group-housed animals

Ten male, pair-housed rhesus macaques (Macaca mulatta) and six female, pair-housed stump-tailed macaques (M. arctoides) were successfully trained to actively cooperate during in-homecage venipuncture. Training was based on positive reinforcement with food-treats and vocal praise, consistent firmness, gentleness and patience....

Year Published: 2002Topics: Animal Training, Biological Sampling & Physiological MeasurementAnimal Type: Macaque, Nonhuman Primate

Citation: Reinhardt, V., Buchanan-Smith, H. M., Prescott, M. J. 2002. Training macaques to voluntarily co-operate during two common procedures: Blood collection and capture of group-housed animals. In: Congress of the International Primatological Society . 182-183 (Abstract). Mammalogical Society of China, Beijing, China.