Anesthesia & Sedation

Comparison of recovery quality following medetomidine versus xylazine balanced isoflurane anaesthesia in horses: A retrospective analysis

Medetomidine partial intravenous anaesthesia (PIVA) has not been compared to xylazine PIVA regarding quality of recovery. This clinical retrospective study compared recoveries following isoflurane anaesthesia balanced with medetomidine or xylazine. The following standard protocol was used: sedation with 7 µg·kg−1...

Year Published: 2021Topics: Anesthesia & SedationAnimal Type: Equine

Citation: Kälin, I., Henze, I. S., Ringer, S. K. et al. 2021. Comparison of recovery quality following medetomidine versus xylazine balanced isoflurane anaesthesia in horses: A retrospective analysis. Animals 11(8), 2440.

The impact of a stress-reducing protocol on the quality of pre-anaesthesia in cats

Introduction: Transport to the clinic is a major source of stress for cats. The process involves being put into a carrier, driven in a car and handled. Cats are therefore removed from the safe-haven of their territory and experience many...

Year Published: 2021Topics: Anesthesia & Sedation, Handling, Relocation & TransportAnimal Type: Cat

Citation: Argüelles, J., Echaniz, M., Bowen, J. et al. 2021. The impact of a stress-reducing protocol on the quality of pre-anaesthesia in cats. Veterinary Record 188(12), e138.

Isoflurane, sevoflurane and desflurane use in cane toads (Rhinella marina)

Anaesthetic chamber concentrations of isoflurane, sevoflurane and desflurane that resulted in loss of righting reflex within 15 minutes in 50 per cent of toads (Rhinella marina) exposed (ED50-LRR

Year Published: 2016Topics: Anesthesia & SedationAnimal Type: Amphibian, Frog & Toad

Citation: Morrison, K.E., Strahl-Heldreth, D. Clark-Price, S.C. 2016. Isoflurane, sevoflurane and desflurane use in cane toads (Rhinella marina). Veterinary Record Open 3(1), e000185.

Comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-detomidine-butorphanol, tiletamine-zolazepam-xylazine-butorphanol, and ketamine-detomidine-butorphanol in pigs

OBJECTIVE: To evaluate and compare the anesthetic, analgesic, and cardiorespiratory effects of tiletamine-zolazepam-detomidine-butorphanol (TZDB), tiletamine-zolazepam-xylazine-butorphanol (TZXB), and ketamine-detomidine-butorphanol (KDB) in pigs and to assess anesthetic recovery duration and quality following administration of tolazoline as a reversal agent. ANIMALS: 11 healthy...

Year Published: 2021Topics: Anesthesia & SedationAnimal Type: Pig

Citation: Chang, L.-J., Ko, J. C., Weil, A. B. et al. 2021. Comparison of anesthetic and cardiorespiratory effects of tiletamine-zolazepam-detomidine-butorphanol, tiletamine-zolazepam-xylazine-butorphanol, and ketamine-detomidine-butorphanol in pigs. Journal of the American Veterinary Medical Association 258(8), 883-891.

Effects of oxygen supplementation on injectable and inhalant anesthesia in C57BL/6 mice

Oxygen supplementation is rarely considered when anesthetizing laboratory mice, despite reports that mice become profoundly hypoxic under anesthesia. Little is known about the effects of hypoxia on anesthetic performance. This article focuses on the effects of oxygen supplementation on physiologic...

Year Published: 2021Topics: Anesthesia & SedationAnimal Type: Mouse, Rodent

Citation: Blevins, C. E., Celeste, N. A., Marx, J. O. 2021. Effects of oxygen supplementation on injectable and inhalant anesthesia in C57BL/6 mice. JAALAS 60(3), 289-297.

An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain

Background: Investigating brain function requires tools and techniques to visualise, modify and manipulate neuronal tissue. One powerful and popular method is intracerebral injection of customised viruses, allowing expression of exogenous transgenes. This technique is a standard procedure for adult mice,...

Year Published: 2020Topics: Anesthesia & SedationAnimal Type: Mouse, Rodent

Citation: Ho, H., Fowle, A., Coetzee, M. et al. 2020. An inhalation anaesthesia approach for neonatal mice allowing streamlined stereotactic injection in the brain. Journal of Neuroscience Methods 342, 108824.

Current topics in marmoset anesthesia and analgesia

Anesthetic and analgesics are essential components of both clinical and research procedures completed in marmosets. A review of current anesthetic and analgesic regimens for marmosets has been complied to provide a concise reference for veterinarians and investigator teams. Published dose...

Year Published: 2020Topics: Anesthesia & SedationAnimal Type: Marmoset, Nonhuman Primate

Citation: Goodroe, A., Fitz, C., Bakker, J. 2020. Current topics in marmoset anesthesia and analgesia. ILAR Journal 61(2-3), 218-229.

Mouse anesthesia: The art and science

There is an art and science to performing mouse anesthesia, which is a significant component to animal research. Frequently, anesthesia is one vital step of many over the course of a research project spanning weeks, months, or beyond. It is...

Year Published: 2021Topics: Anesthesia & SedationAnimal Type: Mouse, Rodent

Citation: Navarro, K. L., Huss, M., Smith, J. C. et al. 2021. Mouse anesthesia: The art and science. ILAR Journal 62(1-2), 238-273.

A suitable anaesthetic protocol for metamorphic zebrafish

Zebrafish are frequently used as a means to investigate development. These studies increasingly require repeated anaesthesia of zebrafish during juvenile (i.e. metamorphic) stages. The effects of anaesthesia during this time remain poorly studied. The aim of this study was to...

Year Published: 2021Topics: Anesthesia & SedationAnimal Type: Fish, Zebrafish

Citation: Owen, J. P., Kelsh, R. N. 2021. A suitable anaesthetic protocol for metamorphic zebrafish. PLOS ONE 16(3), e0246504.

Anesthetic effects of alfaxalone–ketamine, alfaxalone–ketamine–dexmedetomidine, and alfaxalone–butorphanol–midazolam administered intramuscularly in five striped palm squirrels (Funambulus pennantii)

Injectable anesthesia protocols for five striped palm squirrels (Funambulus pennantii) are poorly described in the literature. In this study, male intact squirrels received intramuscular injections of either alfaxalone (6 mg/kg) and ketamine (40 mg/ kg; AK group, n = 8);...

Year Published: 2020Topics: Anesthesia & SedationAnimal Type: Other Rodent, Rodent

Citation: Eshar, D., Beaufrère, H. 2020. Anesthetic effects of alfaxalone–ketamine, alfaxalone–ketamine–dexmedetomidine, and alfaxalone–butorphanol–midazolam administered intramuscularly in five striped palm squirrels (Funambulus pennantii). JAALAS 59(4), 384-392.