Analgesia

Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale

Most research laboratories abide by guidelines and mandates set by their research institution regarding the administration of analgesics to control pain during the postoperative period. Unfortunately, measuring pain originating from the head is difficult, making adequate decisions regarding pain control...

Year Published: 2019Topics: Analgesia, Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Cho, C., Michalidis, V., Lecker, I. et al. 2019. Evaluating analgesic efficacy and administration route following craniotomy in mice using the grimace scale. Scientific Reports 9, 359.

Refinements to captive chimpanzee (Pan troglodytes) care: a self-medication paradigm

In an effort to enhance welfare, behavioural management continually refines methods of non-human primate (NHP) care. Chimpanzees (Pan troglodytes) are one of the most cognitively complex captive NHPs and they have been observed to self-medicate in the wild. The population...

Year Published: 2018Topics: AnalgesiaAnimal Type: Chimpanzee, Nonhuman Primate

Citation: Webb, S. J. N., Hau, J., Schapiro, S. J. 2018. Refinements to captive chimpanzee (Pan troglodytes) care: a self-medication paradigm. Animal Welfare 27(4), 327-341.

Dairy cows under experimentally-induced Escherichia coli mastitis show negative emotional states assessed through Qualitative Behaviour Assessment

Mastitis and associated pain have been identified as a major health and welfare problem affecting dairy cows, however little is known about how cows emotionally experience this illness. Qualitative behaviour assessment (QBA) is a ‘whole animal' methodology for assessing animal...

Year Published: 2018Topics: Analgesia, Welfare AssessmentAnimal Type: Cattle

Citation: de Boyer des Roches, A., Lussert, A., Faure, M. et al. 2018. Dairy cows under experimentally-induced Escherichia coli mastitis show negative emotional states assessed through Qualitative Behaviour Assessment. Applied Animal Behaviour Science 206, 1-11.

Self-administration by consumption of flunixin in feed alleviates the pain and inflammation associated with castration and tail docking of lambs

It can be impractical for farmers to provide pain relief to livestock following husbandry procedures such as castration and tail-docking, particularly in pasture-based systems because animals need to be repeatedly gathered to handling facilities and restrained. We investigated whether voluntary...

Year Published: 2017Topics: AnalgesiaAnimal Type: Sheep

Citation: Marini, D., Colditz, I. G., Hinch, G. et al. 2017. Self-administration by consumption of flunixin in feed alleviates the pain and inflammation associated with castration and tail docking of lambs. Applied Animal Behaviour Science 188, 26-33.

Impact of analgesic drugs on the behavioural responses of larval zebrafish to potentially noxious temperatures

Recent studies have demonstrated that fish exhibit behavioural responses to noxious stimuli, including mechanical, chemical or thermal stimulation. In many cases, these responses are characterised by a reduction in the locomotor activity, which in turn can be ameliorated by using...

Year Published: 2017Topics: AnalgesiaAnimal Type: Fish, Zebrafish

Citation: Lopez-Luna, J., Al-Jubouri, Q., Al-Nuaimy, W. et al. 2017. Impact of analgesic drugs on the behavioural responses of larval zebrafish to potentially noxious temperatures. Applied Animal Behaviour Science 188, 97-105.

Exploring the efficacy of immersion analgesics in zebrafish using an integrative approach

Home Office guidelines recommend the use of analgesics for all protected species, including fish during scientific procedures likely to result in pain, suffering, distress and lasting harm. In larger fish species some drugs have shown efficacy in terms of perioperative...

Year Published: 2017Topics: AnalgesiaAnimal Type: Fish, Zebrafish

Citation: Schroeder, P. G., Sneddon, L. U. 2017. Exploring the efficacy of immersion analgesics in zebrafish using an integrative approach. Applied Animal Behaviour Science 187, 93-102.

Buprenorphine via drinking water and combined oral-injection protocols for pain relief in mice

Buprenorphine is the opioid analgesic most commonly used in laboratory mice. However, to maintain therapeutically effective serum levels, repeated injections are required. To overcome negative aspects of restraint and injection, oral self-administration is a promising alternative but has been criticized...

Year Published: 2016Topics: AnalgesiaAnimal Type: Mouse, Rodent

Citation: Sauer, M., Fleischmann, T., Lipiski, M. et al. 2016. Buprenorphine via drinking water and combined oral-injection protocols for pain relief in mice. Applied Animal Behaviour Science 185, 103-112.

Behavioural responses of fish larvae modulated by analgesic drugs after a stress exposure

Fish are known to respond to a wide range of irritant chemicals, displaying clear behavioural changes after exposure to potentially noxious stimuli. Recent evidence shows that these agents can have an impact on larval forms of fish. However, very little...

Year Published: 2017Topics: AnalgesiaAnimal Type: Fish, Zebrafish

Citation: Lopez-Luna, J., Canty, M. N., Al-Jubouri, Q. et al. 2017. Behavioural responses of fish larvae modulated by analgesic drugs after a stress exposure. Applied Animal Behaviour Science 195, 115-120.

Tramadol:Paracetamol in drinking water for treatment of post-surgical pain in laboratory mice

In the search for stress-free analgesia administration for laboratory mice suffering pain, oral delivery of Tramadol:Paracetamol (T:P) shows great promise. Here, we monitored the analgesic efficacy and side effects of a T:P combination administered solely in the drinking water of...

Year Published: 2018Topics: AnalgesiaAnimal Type: Mouse, Rodent

Citation: Jirkof, P., Arras, M., Cesarovic, N. 2018. Tramadol:Paracetamol in drinking water for treatment of post-surgical pain in laboratory mice. Applied Animal Behaviour Science 198, 95-100.

Evaluating environmental enrichment as a method to alleviate pain after castration and tail docking in pigs

Castration and tail docking are common management practices performed on commercial swine farms in the US and around the world to reduce adverse behaviors and the occurrence of boar taint. However, these practices themselves are a welfare concern for the...

Year Published: 2018Topics: Analgesia, Body Modification/Mutilation, Environmental EnrichmentAnimal Type: Pig

Citation: Backus, B. L., McGlone, J. J. 2018. Evaluating environmental enrichment as a method to alleviate pain after castration and tail docking in pigs. Applied Animal Behaviour Science 204, 37-42.