Publications

Environmental enrichment in the 21st century

More than a quarter of a century has elapsed since the Animal Welfare Act mandated that research facilities develop and follow a plan to promote the psychological well-being of captive primates. Since passage of this law, considerable effort and resources...

Year Published: 2017Topics: Environmental EnrichmentAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Coleman, K., Novak, M. A. 2017. Environmental enrichment in the 21st century. ILAR Journal 58(2), 295-307.

Automated microsampling technologies and enhancements in the 3Rs

Data collected in vivo is essential for advising decisions on drug screening and development and basic research, and animal models are used extensively for acquiring experimental measurements. Traditionally, collection of specimens has been invasive, stressful to animal subjects, labor intensive,...

Year Published: 2016Topics: Biological Sampling & Physiological MeasurementAnimal Type: All/General

Citation: Hopper, L. D. 2016. Automated microsampling technologies and enhancements in the 3Rs. ILAR Journal 57(2), 166-177.

Effects of exercise and enrichment on behaviour in CD-1 mice

A host of scholarly work has characterized the positive effects of exercise and environmental enrichment on behaviour and cognition in animal studies. The purpose of this study was to investigate the uptake and longitudinal impact of exercise and enrichment on...

Year Published: 2018Topics: Emotion, Pain, & Sentience, Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Aujnaraina, A. B., Luoa, O. D., Taylor, N. et al. 2018. Effects of exercise and enrichment on behaviour in CD-1 mice. Behavioural Brain Research 342, 43-50.

Anxiety-like behavior and neuropeptide receptor expression in male and female prairie voles: The effects of stress and social buffering

Strong social support can negate negative health outcomes – an effect defined as ‘social buffering'. In the present study, using the socially monogamous prairie vole (Microtus ochrogaster), we examined whether the presence of a bonded partner during a stressful event...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Other Rodent, Rodent

Citation: Donovan, M., Liu, Y., Wang, Z. 2018. Anxiety-like behavior and neuropeptide receptor expression in male and female prairie voles: The effects of stress and social buffering. Behavioural Brain Research 342, 70-78.

Ethological approach to social isolation effects in behavioral studies of laboratory rodents

The aim of the present review is to discuss how housing conditions affect behavioral performance in laboratory rodents from an ethological view. Commonly used laboratory rodents such as rats and mice, are originally captured animals that largely retain species-typical natural...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Mouse, Rat, Rodent

Citation: Arakawa, H. 2018. Ethological approach to social isolation effects in behavioral studies of laboratory rodents. Behavioural Brain Research 341, 98-108.

Generalization of effects of environmental enrichment on seeking for different classes of drugs of abuse

Background: Addiction is a chronic disease characterized by persistent vulnerability to relapse during abstinence. In animal models of addiction, accumulating evidence suggests that exposure to environmental enrichment (EE) during periods of abstinence can have curative effects on addiction and reduce...

Year Published: 2018Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Sikora, M., Nicolas, C., Istin, M. et al. 2018. Generalization of effects of environmental enrichment on seeking for different classes of drugs of abuse. Behavioural Brain Research 341, 109-113.

Decreased environmental complexity during development impairs habituation of reinforcer effectiveness of sensory stimuli

Previous research has shown that rats reared in simple/impoverished environments demonstrate greater repetitive responding for sensory reinforcers (e.g., light onset). Moreover, the brains of these rats are abnormally developed, compared to brains of rats reared in more complex/enriched environments. Repetitive...

Year Published: 2018Topics: Abnormal/Problematic Behavior, Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Wang, R., Hausknechta, K. A., Haj-Dahmane, S. et al. 2018. Decreased environmental complexity during development impairs habituation of reinforcer effectiveness of sensory stimuli. Behavioural Brain Research 337, 53-60.

Effect of a change in housing conditions on body weight, behavior and brain neurotransmitters in male C57BL/6J mice

The development of modern housing regimes such as individually ventilated cage (IVC) systems has become very popular and attractive in order to reduce spreading of pathogenic organisms and to lower the risk to develop a laboratory animal allergy for staff...

Year Published: 2017Topics: Housing, Social Housing & CompanionshipAnimal Type: Mouse, Rodent

Citation: Pasquarelli, N., Voehringer, P., Henke, J. et al. 2017. Effect of a change in housing conditions on body weight, behavior and brain neurotransmitters in male C57BL/6J mice. Behavioural Brain Research 333, 35-42.

Pavlovian influences on learning differ between rats and mice in a counterbalanced Go/NoGo judgement bias task

Judgement bias tests of animal affect and hence welfare assume that the animal's responses to ambiguous stimuli, which may herald positive or negative outcomes, are under instrumental control and reflect ‘optimism' or ‘pessimism' about what will happen. However, Pavlovian control...

Year Published: 2017Topics: Welfare AssessmentAnimal Type: Mouse, Rat, Rodent

Citation: Jones, S., Paul, E. S., Dayan, P. et al. 2017. Pavlovian influences on learning differ between rats and mice in a counterbalanced Go/NoGo judgement bias task. Behavioural Brain Research 331, 214-224.

Enriched environment alters the behavioral profile of tenascin-C deficient mice

Tenascin-C (TnC) is an extracellular matrix glycoprotein implicated in a variety of processes ranging from brain development to synaptic plasticity in the adult vertebrates. Although the role of the TnC gene in regulation of behavior has been investigated, it remained...

Year Published: 2017Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Stamenkovic, V., Milenkovic, I., Galjak, N. et al. 2017. Enriched environment alters the behavioral profile of tenascin-C deficient mice. Behavioural Brain Research 331, 241-253.