Publications

Welfare measures for laboratory chimpanzees in the United States

Behavioral assessment is an essential element of chimpanzee care. Behavioral data were compiled from four chimpanzee laboratory facilities (N = 522; 286 females, 236 males) using differing methods of assessment including quantitative data collection, animal records and observations by behavioral...

Year Published: 2018Topics: Welfare AssessmentAnimal Type: Chimpanzee, Nonhuman Primate

Citation: Bloomsmith, M. A., Lambeth, S., Lutz, C. et al. 2018. Welfare measures for laboratory chimpanzees in the United States. American Journal of Primatology 80(S1), 46-47 (40th Meeting of the American Society of Primatologists Scientific Program, Abstract #145).

Macroenvironmental effects on the well-being of singly-caged male rhesus macaques (Macaca mulatta)

Determining the effects of the macroenvironment on the welfare of nonhuman primates can help identify their needs and guide their behavioral management. We evaluated the behavior of 37 adult male rhesus macaques in two housing settings at the Tulane National...

Year Published: 2018Topics: Husbandry & ManagementAnimal Type: Macaque, Nonhuman Primate

Citation: Baker, K. C., Ruhde, A. 2018. Macroenvironmental effects on the well-being of singly-caged male rhesus macaques (Macaca mulatta). American Journal of Primatology 80(S1), 47 (40th Meeting of the American Society of Primatologists Scientific Program, Abstract #146).

Amount and reciprocity of affiliative behaviors can predict pairing success in captive rhesus macaques (Macaca mulatta)

Socialization is one of the most important forms of enrichment for rhesus macaques. However, pair introductions can result in aggression and injury if partners are incompatible, even days after the initial introduction. Identifying predictors of long‐term compatibility early on can...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Heagerty, A. L., Coleman, K. 2018. Amount and reciprocity of affiliative behaviors can predict pairing success in captive rhesus macaques (Macaca mulatta). American Journal of Primatology 80(S1), 47 (40th Meeting of the American Society of Primatologists Scientific Program, Abstract #148).

Removals based on low within-matriline relatedness can reduce severe aggression in captive rhesus macaques

Previous observational research of captive rhesus macaques suggests that higher coefficients of relatedness within matrilines are associated with lower rates of severe within‐matriline aggression and more cohesive grooming communities. We tested whether experimental removals targeted to increase the relatedness coefficient...

Year Published: 2018Topics: Husbandry & Management, Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Hanniba, D., Beisner, B., Nathman, A. et al. 2018. Removals based on low within-matriline relatedness can reduce severe aggression in captive rhesus macaques. American Journal of Primatology 80(S1), 48 (40th Meeting of the American Society of Primatologists Scientific Program, Abstract #151).

Social buffering and contact transmission: Network connections have beneficial and detrimental effects on Shigella infection risk among captive rhesus macaques

Group living in primates may impact the risk of pathogen acquisition in two ways. First, social connectedness makes individuals more susceptible to pathogens via contact‐mediated transmission. Yet in strongly bonded societies, having close connections and strong social ties can also...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Macaque, Nonhuman Primate

Citation: Balasubramaniam, K. N., Beisner, B. A., Vandeleest, J. J. et al. 2018. Social buffering and contact transmission: Network connections have beneficial and detrimental effects on Shigella infection risk among captive rhesus macaques. American Journal of Primatology 80(S1), 51-52 (40th Meeting of the American Society of Primatologists Scientific Program, Abstract #162).

Back to Nature! Rehabilitating Danish Research Monkeys

This chapter traces the integration of macaques as experimental organisms for polio in Norway during the 1960s and 1970s. Investigating the integration of macaque monkeys helps to craft an understanding of how political and scientific strategies have been constructed. The...

Year Published: 2016Topics: Relocation & TransportAnimal Type: Macaque, Nonhuman Primate

Citation: Koch, L., Svendsen, S. 2016. Back to Nature! Rehabilitating Danish Research Monkeys. In: Animal Housing and Human-Animal Relations: Politics, Practices and Infrastructures. Edited by K. Bjørkdahl and T. Druglitrø. Routlege: Abingdon, Oxon. Chapter 5 p. 67-81.

No-touch measurements of vital signs in small conscious animals

Measuring the heartbeat and respiration of small conscious animals is important for assessing their health and behavior, but present techniques such as electrocardiogram (ECG), ultrasound, and auscultation rely on close skin contact with the animal. These methods can also require...

Year Published: 2019Topics: Biological Sampling & Physiological MeasurementAnimal Type: All/General

Citation: X. Hui, Kan, E. C. 2019. No-touch measurements of vital signs in small conscious animals. Science Advances 5, eaau0169.

Non-invasive 3D time-of-flight imaging technique for tumour volume assessment in subcutaneous models

Subcutaneous tumour xenograft volumes are generally measured using callipers. This method is susceptible to inter- and intra-observer variability and systematic inaccuracies. Non-invasive 3D measurement using ultrasound and magnetic resonance imaging (MRI) have been considered, but require immobilization of the animal....

Year Published: 2015Topics: Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Delgado San Martin, J. A., Worthington, P., Yates, J. W. T. 2015. Non-invasive 3D time-of-flight imaging technique for tumour volume assessment in subcutaneous models. Laboratory Animals 49(2), 168-171.

Standardized environmental enrichment supports enhanced brain plasticity in healthy rats and prevents cognitive impairment in epileptic rats

Environmental enrichment of laboratory animals influences brain plasticity, stimulates neurogenesis, increases neurotrophic factor expression, and protects against the effects of brain insult. However, these positive effects are not constantly observed, probably because standardized procedures of environmental enrichment are lacking. Therefore,...

Year Published: 2013Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Fares, R. P., Belmeguenai, A., Sanchez, P.E. et al. 2013. Standardized environmental enrichment supports enhanced brain plasticity in healthy rats and prevents cognitive impairment in epileptic rats. PLOS ONE 8(1): e53888.

Larger cages with housing unit environment enrichment improve the welfare of marmosets

The provision of adequate space for laboratory animals is essential not only for good welfare but accurate studies. For example, housing conditions for primates used in biomedical research may negatively affect welfare and thus the reliability of findings. In common...

Year Published: 2018Topics: Environmental Enrichment, HousingAnimal Type: Macaque, Nonhuman Primate

Citation: Yoshimoto, T., Takahashi, E., Yamashita, S. et al. 2018. Larger cages with housing unit environment enrichment improve the welfare of marmosets. Experimental Animals 67(1), 31-39.