Publications

Association of Primate Veterinarians’ guidelines for nonhuman primate restraint

The Association of Primate Veterinarians (APV) recognizes that several forms of restraint, including physical and chemical, are necessary for the safe handling of nonhuman primates (NHPs). The following guidelines aim to provide information to researchers, animal caregivers, veterinarians, and institutional...

Year Published: 2019Topics: RestraintAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Association of Primate Veterinarians. 2019. Association of Primate Veterinarians' guidelines for nonhuman primate restraint. JAALAS 58(3), 282-284.

Time-dependent pathologic and inflammatory consequences of various blood sampling techniques in mice

We compared 6 frequently used mouse blood-sampling methods (lateral tail incision; tail-tip amputation; sublingual, submandibular, and saphenous vein puncture; and retrobulbar sinus puncture during isoflurane anesthesia) with regard to induction of local and systemic inflammation, stomach contents, weight changes, and...

Year Published: 2019Topics: Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rodent

Citation: Sørensen, D. B., Metzdorff, S. B., Jensen, L. K. et al. 2019. Time-dependent pathologic and inflammatory consequences of various blood sampling techniques in mice. JAALAS 58(3), 362-372.

Assessment of pain associated with the injection of sodium pentobarbital in laboratory mice (Mus musculus)

The AVMA Guidelines for the Euthanasia of Animals considers injection of barbiturates to be an acceptable method of euthanasia in rodents but states there is a potential for pain when administered intraperitoneally. This study examined the potential for pain in...

Year Published: 2019Topics: Drug/Substance Administration, EuthanasiaAnimal Type: Mouse, Rodent

Citation: Dutton III, J. W., Artwohl, J. E., Huang, X. et al. 2019. Assessment of pain associated with the injection of sodium pentobarbital in laboratory mice (Mus musculus). JAALAS 58(3), 373-379.

Clinical, physiologic, and behavioral evaluation of permanently catheterized NMRI mice

Vascular catheterization is becoming a popular technique in laboratory rodents, facilitating repetitive blood sampling and infusion in individual animals. In mice, catheterization is complicated by their small body size, which may increase the risk of postoperative complications that may both...

Year Published: 2019Topics: Cannulation, Catheterization, & IntubationAnimal Type: Mouse, Rodent

Citation: Falkenberg, M. K., Teilmann, A. C., Henriksen, T. et al. 2019. Clinical, physiologic, and behavioral evaluation of permanently catheterized NMRI mice. JAALAS 58(3), 380-389.

Compassion fatigue, euthanasia stress, and their management in laboratory animal research

This review is designed to assist both individuals and organizations involved in animal-based research to understand and appreciate the importance and potential risks of compassion fatigue and euthanasia stress. We reviewed current literature regarding compassion fatigue and euthanasia stress as...

Year Published: 2019Topics: Human-Animal InteractionAnimal Type: All/General

Citation: Newsome, J. T., Clemmons, E. A., Fitzhugh, D. C. et al. 2019. Compassion fatigue, euthanasia stress, and their management in laboratory animal research. JAALAS 58(3), 289-292.

Human infant pants for postoperative protection during social housing of New Zealand white rabbits (Oryctolagus cuniculus)

Elizabethan collars (E-collars) are commonly used in various species to safeguard healing wounds. However, E-collars inadvertently restrict the expression of normal species-typical behaviors, including coprophagy, self-grooming, and social housing. To maintain social housing in accordance with recommendations in the 8th...

Year Published: 2019Topics: Disease/Experimental Model, Social Housing & CompanionshipAnimal Type: Rabbit

Citation: Bartley, K. A., Johnson, C. H. 2019. Human infant pants for postoperative protection during social housing of New Zealand white rabbits (Oryctolagus cuniculus). JAALAS 58(4), 510-516.

The role of emotional contagion in the distress exhibited by grouped mice exposed to CO2

The 2013 AVMA Guidelines for the Euthanasia of Animals recommends a chamber volume displacement rate of 10% to 30% per minute (v/min) when euthanizing small laboratory rodents with CO2. Group euthanasia of mice is a common practice, and grouping strangers...

Year Published: 2019Topics: EuthanasiaAnimal Type: Mouse, Rodent

Citation: Moffitt, A. D., Brignolo, L. L., Ardeshir, A. et al. 2019. The role of emotional contagion in the distress exhibited by grouped mice exposed to CO2. JAALAS 58(4), 430-437.

Physiologic stress of ear punch identification compared with restraint only in mice

Social housing of laboratory rodents is recommended whenever possible to encourage natural behavior and social dynamics. Several identification methods are used to distinguish rodents from one another. One of the most common means of identifying mice is ear punching. The...

Year Published: 2019Topics: Identification MethodAnimal Type: Mouse, Rodent

Citation: Taitt, K. T., Kendall, L. V. 2019. Physiologic stress of ear punch identification compared with restraint only in mice. JAALAS 58(4), 438-442.

Evaluation of a 16-week change cycle for ventilated mouse cages

The methods and conditions for housing research mice have been the subject of many discussions and publications in recent years. At our institution, we began to explore these matters with the goal of reducing stress in the animals and yet...

Year Published: 2019Topics: Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Taylor, J. L., Noel, P., Mickelsen, M. 2019. Evaluation of a 16-week change cycle for ventilated mouse cages. JAALAS 58(4), 443-449.

Refinements of equipment and methodology to reduce risk during pole-guided chair transfer of nonhuman primates

Neurophysiologic studies of NHP commonly involve their transfer from a housing enclosure to a laboratory by using a mobile chair. This transfer should be performed in a manner that is safe and minimizes stress for both animal and handler. The...

Year Published: 2019Topics: HandlingAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Squirrel Monkey, Vervet (African Green Monkey)

Citation: McIntosh, M. K., Armitage-Brown, B., Levy, R. 2019. Refinements of equipment and methodology to reduce risk during pole-guided chair transfer of nonhuman primates. JAALAS 58(4), 462-468.