Publications

Effects of analgesics on tumor growth in mouse models of prostate cancer bone metastasis

Murine models of tumor development often require invasive procedures for tumor implantation, potentially causing pain or distress. However, analgesics are often withheld during implantation because of concerns that they may adversely affect tumor development. Previous studies examining the effects of...

Year Published: 2021Topics: Disease/Experimental ModelAnimal Type: Mouse, Rodent

Citation: Xu, J. J., Thurston, S. E., Robinson, T. J. et al. 2021. Effects of analgesics on tumor growth in mouse models of prostate cancer bone metastasis. JAALAS 60(3), 341-348.

Effects of pair housing on patency of jugular catheters in rats (Rattus norvegicus)

Chronic vascular access devices are widely used in a variety of species for repeated blood sampling or substance administration. Jugular catheters are commonly used for studying addiction-related behaviors in rats. Rats with catheters have historically been individually housed for the...

Year Published: 2021Topics: Cannulation, Catheterization, & Intubation, External Bodily Equipment, Social Housing & CompanionshipAnimal Type: Rat, Rodent

Citation: Krueger, L. D., Chang, S. E., Motoc, M. et al. 2021. Effects of pair housing on patency of jugular catheters in rats (Rattus norvegicus). JAALAS 60(3), 357-364.

The use of a species-specific health and welfare assessment tool for the giant Pacific octopus, Enteroctopus dofleini

Cephalopods are increasingly viewed as sentient animals that require the same welfare consideration as their vertebrate counterparts. In this study, an observational welfare assessment tool developed by the EU Directive was revised to be species-specific for the giant Pacific octopus,...

Year Published: 2021Topics: Welfare AssessmentAnimal Type: Cephalopod, Invertebrate

Citation: Holst, M. M., Miller-Morgan, T. 2021. The use of a species-specific health and welfare assessment tool for the giant Pacific octopus, Enteroctopus dofleini, Journal of Applied Animal Welfare Science 24(3), 272-291.

Taste preferences and feeding behaviour in the facultative herbivorous fish, Nile tilapia Oreochromis niloticus

Taste preferences in fishes are known mainly for carnivorous species, whereas herbivorous consumers were rarely used in such studies. The main goal of the present study was to evaluate the taste preferences in the herbivorous African cichlid fish, Nile tilapia...

Year Published: 2021Topics: Husbandry & ManagementAnimal Type: Fish, Tilapia

Citation: Levina, A. D., Mikhailova, E. S., Kasumyan, A. O. 2021. Taste preferences and feeding behaviour in the facultative herbivorous fish, Nile tilapia Oreochromis niloticus. Journal of Fish Biology 98(5), 1385-1400.

Plasticity of the skeleton and skeletal deformities in zebrafish (Danio rerio) linked to rearing density

The teleost zebrafish (Danio rerio), an established model for human skeletal diseases, is reared under controlled conditions with defined parameters for temperature and photoperiod. Studies aimed at defining the proper rearing density have been performed with regard to behavioural and...

Year Published: 2021Topics: Stocking DensityAnimal Type: Fish, Zebrafish

Citation: Martini, A., Huysseune, A., Witten, P. E. et al. 2021. Plasticity of the skeleton and skeletal deformities in zebrafish (Danio rerio) linked to rearing density. Journal of Fish Biology 98(4), 971-986.

Reducing suffering in experimental autoimmune encephalomyelitis (EAE)

This report is based on discussions and submissions from an expert working group consisting of veterinarians, animal care staff and scientists with expert knowledge relevant to the field. It aims to facilitate the implementation of the Three Rs (replacement, reduction...

Year Published: 2013Topics: Disease/Experimental ModelAnimal Type: Dog, Guinea Pig, Hamster, Macaque, Marmoset, Mouse, Nonhuman Primate, Rabbit, Rat, Rodent, Sheep

Citation: Wolfensohn, S., Hawkins, P., Lilley, E. et al. 2013. Reducing suffering in experimental autoimmune encephalomyelitis (EAE). Journal of Pharmacological and Toxicological Methods 67(3), 169-176.

Assessment of behaviour in groups of zebrafish (Danio rerio) using an intelligent software monitoring tool, the chromatic fish analyser

Background: Zebrafish (Danio rerio) are an increasingly popular model species within a variety of biomedical and neurobiological contexts. Researchers are required to prevent any negative states, such as pain, when using experimental animals to optimise fish welfare but analysis tools...

Year Published: 2019Topics: Welfare AssessmentAnimal Type: Fish, Zebrafish

Citation: Thomson, J. S., Al-Temeemy, A. A., Isted, H. et al. 2019. Assessment of behaviour in groups of zebrafish (Danio rerio) using an intelligent software monitoring tool, the chromatic fish analyser. Journal of Neuroscience Methods 328, 108433.

Individually customisable non-invasive head immobilisation system for non-human primates with an option for voluntary engagement

Background: Head immobilisation is often necessary for neuroscientific procedures. A number of Non-invasive Head Immobilisation Systems (NHIS) for monkeys are available, but the need remains for a feasible integrated system combining a broad range of essential features. New Method: We...

Year Published: 2016Topics: External Bodily EquipmentAnimal Type: Macaque, Nonhuman Primate

Citation: Slater, H., Milne, A. E., Wilson, B. et al. 2016. Individually customisable non-invasive head immobilisation system for non-human primates with an option for voluntary engagement. Journal of Neuroscience Methods 269, 46-60.

The development of a non-invasive behavioral model of thermal heat stress in laboratory mice (Mus musculus)

Background: Many behavioral and physiological studies of laboratory mice employ invasive methods such as radio telemetry to measure key aspects of behavior and physiology. Radio telemetry requires surgical implants, which may impact mouse health and behavior, and thus reduce the...

Year Published: 2016Topics: Disease/Experimental ModelAnimal Type: Mouse, Rodent

Citation: Mufford, J. T., Paetkau, M.J., Flood, N.J. et al. 2016. The development of a non-invasive behavioral model of thermal heat stress in laboratory mice (Mus musculus). Journal of Neuroscience Methods 268, 189-195.

Protective cranial implant caps for macaques

Background: Neuroscience studies with macaque monkeys may require cranial implants to stabilize the head or gain access to the brain for scientific purposes. Wound management that promotes healing after the cranial implant surgery in non-human primates can be difficult as...

Year Published: 2021Topics: External Bodily EquipmentAnimal Type: Macaque, Nonhuman Primate

Citation: Perry, B. A. L., Mason, S., Nacef, J. et al. 2021. Protective cranial implant caps for macaques. Journal of Neuroscience Methods 348, 108992.