Rodent

Rat playpens—The effect on welfare, technical time and budget

Year Published: 2023Topics: Environmental Enrichment, HousingAnimal Type: Rat, Rodent

Citation: Tough, B. 2023, August. Rat playpens—The effect on welfare, technical time and budget. Animal Technology and Welfare 22(2), 156–157.

Social enrichment improves social recognition memory in male rats

The social environment is thought to have a strong impact on cognitive functions. In the present study, we investigated whether social enrichment could affect rats' memory ability using the “Different Objects Task (DOT),” in which the levels of memory load...

Year Published: 2018Topics: Social Housing & CompanionshipAnimal Type: Rat, Rodent

Citation: Toyoshima, M., Yamada, K., Sugita, M. et al. 2018. Social enrichment improves social recognition memory in male rats. Animal Cognition 21(3), 345–351.

A fine-scale and minimally invasive marking method for use with conventional tungsten microelectrodes

In neurophysiology, achieving precise correlation between physiological responses and anatomic structures is a significant challenge. Therefore, the accuracy of the electrode marking method is crucial. In this study, we describe a tungsten-deposition method, in which tungsten oxide is generated by...

Year Published: 2023Topics: Imaging & Electrophysiological RecordingAnimal Type: Macaque, Mouse, Nonhuman Primate, Rodent

Citation: Oikawa, T., Nomura, K., Hara, T. et al. 2023. A fine-scale and minimally invasive marking method for use with conventional tungsten microelectrodes. eNeuro 10(9), ENEURO.0141-23.2023.

Making a case for the free exploratory paradigm: Animal welfare-friendly assays that enhance heterozygosity and ecological validity

Rodents, laboratory rats and mice, have been used as models in experimental research for almost two centuries (Keeler, 1947; Bolles and Woods, 1964; Nishioka, 1995; Guénet and Bonhomme, 2003). During this time, it has been assumed that rodent suffering was...

Year Published: 2023Topics: Behavioral & Cognitive TestingAnimal Type: Mouse, Rat, Rodent

Citation: Parsons, M. H., Stryjek, R., Fendt, M. et al. 2023. Making a case for the free exploratory paradigm: Animal welfare-friendly assays that enhance heterozygosity and ecological validity. Frontiers in Behavioral Neuroscience 17.

Refining stereotaxic neurosurgery techniques and welfare assessment for long-term intracerebroventricular device implantation in rodents

Stereotaxic surgeries enable precise access to specific brain regions, being of particular interest for chronic intracerebroventricular drug delivery. However, the challenge of long-term studies at this level is to allow the implantation of drug storage devices and their correct intrathecal...

Year Published: 2023Topics: External Bodily EquipmentAnimal Type: Mouse, Rodent

Citation: Pérez-Martín, E., Coto-Vilcapoma, A., Castilla-Silgado, J. et al. 2023. Refining stereotaxic neurosurgery techniques and welfare assessment for long-term intracerebroventricular device implantation in rodents. Animals 13(16), 2627.

Evidence-based comparative severity assessment in young and adult mice

In animal-based research, welfare assessments are essential for ethical and legal reasons. However, accurate assessment of suffering in laboratory animals is often complicated by the multidimensional character of distress and pain and the associated affective states. The present study aimed...

Year Published: 2023Topics: Welfare AssessmentAnimal Type: Mouse, Rodent

Citation: Reiber, M., Schumann, L. von, Buchecker, V. et al. 2023. Evidence-based comparative severity assessment in young and adult mice. PLOS ONE 18(10), e0285429.

Effects of early noise exposure on hippocampal-dependent behaviors during adolescence in male rats: Influence of different housing conditions

Central nervous system (CNS) development is a very complex process that can be altered by environmental stimuli such as noise, which can generate long-term auditory and/or extra-auditory impairments. We have previously reported that early noise exposure can induce hippocampus-related behavioral...

Year Published: 2022Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Molina, S. J., Lietti, Á. E., Carreira Caro, C. S. et al. 2022. Effects of early noise exposure on hippocampal-dependent behaviors during adolescence in male rats: Influence of different housing conditions. Animal Cognition 25(1), 103–120.

Animal-friendly behavioral testing in field studies: Examples from ground squirrels

Field studies of behavior provide insight into the expression of behavior in its natural ecological context and can serve as an important complement to behavioral studies conducted in the lab under controlled conditions. In addition to naturalistic observations, behavioral testing...

Year Published: 2023Topics: Behavioral & Cognitive TestingAnimal Type: Other Rodent, Rodent

Citation: Nunes, S. 2023. Animal-friendly behavioral testing in field studies: Examples from ground squirrels. Frontiers in Behavioral Neuroscience 17.

Non-invasive quantification of faecal and urine reproductive hormone metabolites in the naked mole-rat (Heterocephalus glaber)

The naked mole-rat (Heterocephalus glaber) occurs in colonies with a distinct dominance hierarchy, including one dominant, breeding female (the queen), 1–3 breeding males, and non-reproductive subordinates of both sexes that are reproductively suppressed while in the colony. To non-invasively evaluate...

Year Published: 2023Topics: Biological Sampling & Physiological MeasurementAnimal Type: Rat, Rodent

Citation: Majelantle, T. L., Ganswindt, A., Ganswindt, S. B. et al. 2023. Non-invasive quantification of faecal and urine reproductive hormone metabolites in the naked mole-rat (Heterocephalus glaber). Animals 13(19), 3039.

Acclimation and blood sampling: Effects on stress markers in C57Bl/6J mice

Blood sampling in rodents is common practice in scientific studies. Some of the refined methods widely used are the puncture of the saphenous vein or tail vein, or even tail docking. The handling needs of these different blood sampling methods...

Year Published: 2023Topics: Biological Sampling & Physiological MeasurementAnimal Type: Mouse, Rodent

Citation: Marin, N., Moragon, A., Gil, D. et al. 2023. Acclimation and blood sampling: Effects on stress markers in C57Bl/6J mice. Animals 13(18), 2816.