Rodent

Rat ultrasound and welfare assessment: Preliminary results

A great deal of further research will be necessary before ultrasonic vocalisation can be used to help assess pain and/or distress in the rat.

Year Published: 2005Animal Type: Rat, Rodent

Citation: Nicholson, J. 2005. Rat ultrasound and welfare assessment: Preliminary results. Animal Technology and Welfare 4, 79-80.

The effect of training for long term restraining of rats evaluated by telemtry

Cardiovsacular stress responses were significant on all ten days of 3-hour tube restraint periods.

Year Published: 2005Animal Type: Rat, Rodent

Citation: Mikkelsen, L. F., Dragsted, N., Hansen, A. K. et al. 2005. The effect of training for long term restraining of rats evaluated by telemtry. Alternatives to Animal Experimentation [ALTEX] 22, 53 (Abstract).

Breeding colony housing: A comparison of two cages sized

Based on our findings we determined that large boxes [8 x 17 in. versus small 6 x 10 in. standard boxes] improved breeding performance [of breeding C57BL/6 mice], required less labor, and provided a better microenvironment.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: McMahon, K., Haist, C., Dysko, R. 2005. Breeding colony housing: A comparison of two cages sized. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 127(Abstract).

Collecting blood from rodents: A discussion by the Laboratory Animal Refinement and Enrichment Forum

The question was asked: "In your own experience, what is the least disturbing technique - from the subject's point of view! - of blood collection for rodents?" In summary, it is fair to conclude the clinical and ethical concerns outweigh...

Year Published: 2005Topics: Biological Sampling & Physiological MeasurementAnimal Type: Chinchilla, Gerbil, Guinea Pig, Hamster, Mouse, Other Rodent, Rat, Rodent

Citation: Luzzi, M., Skoumbourdis, E., Baumans, V. et al. 2005. Collecting blood from rodents: A discussion by the Laboratory Animal Refinement and Enrichment Forum. Animal Technology and Welfare 4, 99-102.

Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice

Cerebral deposition of beta-amyloid (Abeta) peptides is an invariant pathological hallmark in brains of patients with Alzheimer's disease (AD) and transgenic mice coexpressing familial AD-linked APP and PS1 variants. We now report that exposure of transgenic mice to an enriched...

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Lazarov, O., Robinson, J., Tang, Y. P. et al. 2005. Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice. Cell 120, 701-713.

Nest-building behaviour in male rats from three inbred strains: BN/HsdCpb, BDIX/OrIIco and LEW/Mol

It was demonstrated in three inbred strains [BN, BDIX, LEW] of pair-housed male rats that naive animals who never had access to any kind of nesting material do build nests if the correct stimuli are provided. The animals were housed...

Year Published: 2005Animal Type: Rat, Rodent

Citation: Jegstrup, I. M., Vestergaard, R., Vach, W. et al. 2005. Nest-building behaviour in male rats from three inbred strains: BN/HsdCpb, BDIX/OrIIco and LEW/Mol. Animal Welfare 14, 149-156.

Environmental enrichment for laboratory rodents

In this article, laws and guidelines relating to rodent enrichment are reviewed, the natural behaviors of select rodent species are discussed, and an overview of widely used types of enrichment in laboratory rodent management is provided. Survey data on current...

Year Published: 2005Topics: Environmental Enrichment, Natural Behavior, Regulations & Ethical ReviewAnimal Type: Guinea Pig, Hamster, Mouse, Rat, Rodent

Citation: Hutchinson, E., Avery, A., Van de Woude, S. 2005. Environmental enrichment for laboratory rodents. ILAR Journal 46(2), 148-161.

Report of the 2004 RSPCA/UFAW rodent welfare group meeting

Year Published: 2005Animal Type: Rodent

Citation: Hawkins, P., Nicholson, J., Burn, C. et al. 2005. Report of the 2004 RSPCA/UFAW rodent welfare group meeting. Animal Technology and Welfare 4, 79-89.

Husbandry of an atypical animal research model: The degu (Octodon degus)

Useful tips on the behavior, handling, diet, breeding and environmental enrichment of degus: One of the most important aspects to consider when housing the degu is social behavior. Animals should be pair housed, either as a breeding pair or same...

Year Published: 2005Topics: Husbandry & ManagementAnimal Type: Other Rodent, Rodent

Citation: Haight, J. 2005. Husbandry of an atypical animal research model: The degu (Octodon degus). Tech Talk [The Newsletter for Laboratory Animal Science Technicians] 10(6).

Using obese mouse models in research: Special considerations for IACUC members, animal care technicians, and researchers

General discussion of husbandry issues specifically related to obese mice.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Good, D. J. 2005. Using obese mouse models in research: Special considerations for IACUC members, animal care technicians, and researchers. Lab Animal 34(2), 30-37.