Rodent

Gerbil tube comparison

Gerbils destructed PC [polycarbonate] tubes much more intensively than PCV [polyvinylchloride] tubes.

Year Published: 2001Animal Type: Gerbil, Rodent

Citation: Lee, L., Hughes, R. 2001. Gerbil tube comparison. Tech Talk [The Newsletter for Laboratory Animal Science Technicians] 6(4), 3.

The use of radiotelemetry in small laboratory animals: Recent advances

Radiotelemetry provides an alternative means of obtaining physiological measurements from awake and freely moving laboratory animals, without introducing stress artifacts. For researchers, especially those in the fields of pharmacology and toxicology, the technique may provide a valuable tool for predicting...

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Kramer, K., Kinter, L., Brockway, B. et al. 2001. The use of radiotelemetry in small laboratory animals: Recent advances. Contemporary Topics in Laboratory Animal Science 40(1), 8-16.

Training could prevent deaths due to rodent gavage procedure

We were surprised and shocked to note that 5 of 9 (56%) of the rats gavaged without anesthesia/sedation died within 10 days. The animals experienced gavage-related weight loss probably due to gavage-related injury leading to decreased food consumption. [in reference...

Year Published: 2001Animal Type: Rat, Rodent

Citation: Rao, G. N., Peace, T. A., Hoskins, D. E. 2001. Training could prevent deaths due to rodent gavage procedure. Contemporary Topics in Laboratory Animal Science 40(4), 7-8.

Does conditioning influence the increase of heart rate and body temperature as provoked by handling in the mouse? Contemporary Topics in Laboratory Animal Science 40(4), 92 (Abstract)

Handling of mice or cleaning their cages results in an acute increase in heart rate (HR) and body temperature (BT). ... From the results it can be concluded that entering the animals' room even without performing handling procedures, increases HR...

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Kramer, K., Mulder, A., van de Weerd, H. et al. 2001. Does conditioning influence the increase of heart rate and body temperature as provoked by handling in the mouse? Contemporary Topics in Laboratory Animal Science 40(4), 92 (Abstract).

Future principles for the housing and care of laboratory rodents: An insider’s experience

The Expert Group also stressed that although animals need a minimum space in order to be able to perform their basic behaviours, increasing amounts of empty space without proper enrichment may stimulate territorial aggression. ... Solid floors are preferable to...

Year Published: 2001Topics: HousingAnimal Type: Rodent

Citation: Peters, A. 2001. Future principles for the housing and care of laboratory rodents: An insider's experience. Animal Technology 52, 37-38.

The effect of sampling technique on pharmacokinetic parameters in rats: A comparison of tradition blood sampling methods with an automated sampler

The condition of the animal during collection of such fluids [blood, bile, urine, cerebrospinal fluid] may influence metabolism or excretion of the drug. Specifically, conditions that accelerate blood pressure, heart rate and endogenous metabolism can be expected to affect xenobiotic...

Year Published: 2001Animal Type: Rat, Rodent

Citation: Kissinger, C. B., Cregor, M., Hilt, R. et al. 2001. The effect of sampling technique on pharmacokinetic parameters in rats: A comparison of tradition blood sampling methods with an automated sampler. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 89 (Abstract).

Enrichment of laboratory rat caging

Social contact seems to be the most important enrichment. Rats show higher demand for contact with three familiar rats, than for larger cages or toys. .. Rats show T-maze preferences for larger cages whether alone or with four cage-mates. .....

Year Published: 2001Topics: Environmental Enrichment, Housing, Social Housing & CompanionshipAnimal Type: Rat, Rodent

Citation: Patterson-Kane, E. G., van de Ven, M., Ras, T. 2001. Enrichment of laboratory rat caging . American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 106 (Abstract).

Report of the 2000 RSPCA/UFAW Rodent Welfare Group meeting

The following presentations are included in this database: A regulatory viewpoint on environmental stimulation in preclinical toxicology studies, by Jones D; Environmental enrichment for animals used in GLP [Good Laboratory Practice] toxicological studies, by Harding K; Escape behaviour in laboratory...

Year Published: 2001Animal Type: Mouse, Rat, Rodent

Citation: Hawkins, P., Berdoy, M., Deacon, R. et al. 2001. Report of the 2000 RSPCA/UFAW Rodent Welfare Group meeting. Animal Technology 52, 29-42.

Effects of caging type and animal source on the development of foot lesions in Sprague Dawley rats (Rattus norvegicus)

Noteworthy abnormalities of the plantar surface of the hind foot (i.e., ulcers or nodular swellings) were more common in heavierrats than in lighter animals of the same sex (but different source), and abnormalities were more common in rats housed in...

Year Published: 2001Animal Type: Rat, Rodent

Citation: Peace, T. A., Singer, A. W. 2001. Effects of caging type and animal source on the development of foot lesions in Sprague Dawley rats (Rattus norvegicus). Contemporary Topics in Laboratory Animal Science 40(5), 17-21.

Therepeutic effects of environmental enrichment on cognitive function and tissue integrity following severe traumatic brain injury in rats

These results indicate that noninvasive environmental stimulation is beneficial in attenuating cognitive deficits and preserving tissue integrity in a TBI model which causes cerebral contusion and cell death.

Year Published: 2001Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Passineau, M. J., Green, E. J., Dietrich, W. D. 2001. Therepeutic effects of environmental enrichment on cognitive function and tissue integrity following severe traumatic brain injury in rats. Experimantal Neurology 168, 373-384.