Rodent

The effect of sampling technique on pharmacokinetic parameters in rats: A comparison of tradition blood sampling methods with an automated sampler

The condition of the animal during collection of such fluids [blood, bile, urine, cerebrospinal fluid] may influence metabolism or excretion of the drug. Specifically, conditions that accelerate blood pressure, heart rate and endogenous metabolism can be expected to affect xenobiotic...

Year Published: 2001Animal Type: Rat, Rodent

Citation: Kissinger, C. B., Cregor, M., Hilt, R. et al. 2001. The effect of sampling technique on pharmacokinetic parameters in rats: A comparison of tradition blood sampling methods with an automated sampler. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 89 (Abstract).

Enrichment of laboratory rat caging

Social contact seems to be the most important enrichment. Rats show higher demand for contact with three familiar rats, than for larger cages or toys. .. Rats show T-maze preferences for larger cages whether alone or with four cage-mates. .....

Year Published: 2001Topics: Environmental Enrichment, Housing, Social Housing & CompanionshipAnimal Type: Rat, Rodent

Citation: Patterson-Kane, E. G., van de Ven, M., Ras, T. 2001. Enrichment of laboratory rat caging . American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 106 (Abstract).

Report of the 2000 RSPCA/UFAW Rodent Welfare Group meeting

The following presentations are included in this database: A regulatory viewpoint on environmental stimulation in preclinical toxicology studies, by Jones D; Environmental enrichment for animals used in GLP [Good Laboratory Practice] toxicological studies, by Harding K; Escape behaviour in laboratory...

Year Published: 2001Animal Type: Mouse, Rat, Rodent

Citation: Hawkins, P., Berdoy, M., Deacon, R. et al. 2001. Report of the 2000 RSPCA/UFAW Rodent Welfare Group meeting. Animal Technology 52, 29-42.

Effects of caging type and animal source on the development of foot lesions in Sprague Dawley rats (Rattus norvegicus)

Noteworthy abnormalities of the plantar surface of the hind foot (i.e., ulcers or nodular swellings) were more common in heavierrats than in lighter animals of the same sex (but different source), and abnormalities were more common in rats housed in...

Year Published: 2001Animal Type: Rat, Rodent

Citation: Peace, T. A., Singer, A. W. 2001. Effects of caging type and animal source on the development of foot lesions in Sprague Dawley rats (Rattus norvegicus). Contemporary Topics in Laboratory Animal Science 40(5), 17-21.

Therepeutic effects of environmental enrichment on cognitive function and tissue integrity following severe traumatic brain injury in rats

These results indicate that noninvasive environmental stimulation is beneficial in attenuating cognitive deficits and preserving tissue integrity in a TBI model which causes cerebral contusion and cell death.

Year Published: 2001Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Passineau, M. J., Green, E. J., Dietrich, W. D. 2001. Therepeutic effects of environmental enrichment on cognitive function and tissue integrity following severe traumatic brain injury in rats. Experimantal Neurology 168, 373-384.

Environmental enrichment for laboratory rats: A review

In the laboratory, rats have been found to benefit from social contact, shelters, nesting material, objects for gnawing and large, complex cages whilst the provision of toys or open space is largely unsuccessful.

Year Published: 2001Animal Type: Rat, Rodent

Citation: Patterson-Kane, E. G. 2001. Environmental enrichment for laboratory rats: A review. Animal Technology 52, 77-84.

The cage preferences of laboratory rats

The rats did not show significant preferences for most of the options [e.g., toys] over an empty cage. The exceptions were shredded paper, a nesting box and a semi-enriched condition incorporating a range of modifications.

Year Published: 2001Animal Type: Rat, Rodent

Citation: Patterson-Kane, E. G., Harper, D. N., Hunt, M. 2001. The cage preferences of laboratory rats. Laboratory Animals 35, 74-79.

Revolutionary Science: An improved running wheel for hamsters and mice

Golden hamsters and mice ran more in wheels with the floor covered with plastic mesh than in wheels with the usual metal rods. Small diameter wheels were preferred less than standard 17.5-cm wheels.

Year Published: 2001Animal Type: Hamster, Mouse, Rodent

Citation: Mrosovsky, N., Salmon, P., White, N. 2001. Revolutionary Science: An improved running wheel for hamsters and mice. CALAS/ACSAL Symposium, 29 (Abstract).

Modulation of aggression in male mice – Influence of group size and cage size

It is concluded that aggressive behaviour in group-housed male BALB/c mice is best prevented by housing the animals in small groups of three animals, while decreasing floor size per animal may be used as a temporary solution to decrease high...

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Van Loo, P. L. P., Mol, J. A., Koolhaas, J. M. et al. 2001. Modulation of aggression in male mice - Influence of group size and cage size. Physiology and Behavior 72, 675-683.

Male Management – Coping With Aggression Problems in Male Laboratory Mice (Doctoral Thesis)

The purpose of this thesis was to find practical solutions for coping with excessive aggressive behaviour in male laboratory mice. .. The proximity of another male is preferred to individual housing, irrespectively of dominance status, kinship or familiarity. ... Male...

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Van Loo, P. L. P. 2001. Male Management - Coping With Aggression Problems in Male Laboratory Mice (Doctoral Thesis). University of Utrecht, Diest, Belgium.