Rodent

The development of a novel form of mouse cage enrichment

We incorporated a number of existing enrichments into a one-piece insert which covers the entire cage base and comprises two raised platforms and an in-build shelter. This design of combining a shelter and [high and low] platforms into one insert...

Year Published: 2000Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Leach, M. C., Ambrose, N., Bowell, V. J. et al. 2000. The development of a novel form of mouse cage enrichment. Journal of Applied Animal Welfare Science 3, 81-91.

The effects of enrichment on parameters in hypertensive rats

The study showed that male SHR rats who were each housed with another rat were more active and had a higher systolic pressure than did similar animals housed alone. Diastolic blood pressure or heart rate did not differ. .. Separation...

Year Published: 2000Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Lawson, D. M., Churchill, P. C., Churchill, P. C. 2000. The effects of enrichment on parameters in hypertensive rats . Contemporary Topics in Laboratory Animal Science 39(1), 9-13.

Long-term environmental enrichment leads to regional increase in neurotrophin levels in rat brain

These findings demonstrate significant alterations in NGF, and NT-3 protein levels in several brain regions as a result of an enriched versus an isolated environment and thus provide a possible biochemical basis for behavioral and alterations that have been found...

Year Published: 2000Topics: Environmental EnrichmentAnimal Type: Rat, Rodent

Citation: Ickes, B. R., Pham, T. M., Sanders, L. A. et al. 2000. Long-term environmental enrichment leads to regional increase in neurotrophin levels in rat brain. Experimental Neurology 164, 45-52.

Housing for Laboratory Rats, Mice, Guinea Pigs and Rabbits

General recommendations for the species-adequate housing of rats, mice, guinea pigs and rabbits

Year Published: 2000Animal Type: Guinea Pig, Mouse, Rabbit, Rat, Rodent

Citation: Hargreaves, A. L. 2000. Housing for Laboratory Rats, Mice, Guinea Pigs and Rabbits. Australian and New Zealand Council for the Care of Animals in Research and Testing, Wellington, New Zealand.

Use of PVC conduits by rats of various strains and ages housed singly and in pairs

Adult male Long-Evans rats rarely entered PVC conduits unless housed in pairs. ... Adult male Sprague-Dawley rats entered PVC conduits only during the illuminated portion of the day-night cycle and only if housed on shelves exposed to direct overhead illumination....

Year Published: 2000Animal Type: Rat, Rodent

Citation: Galef, Jr. B. G., Sorge, R. E. 2000. Use of PVC conduits by rats of various strains and ages housed singly and in pairs. Journal of Applied Animal Welfare Science 3, 279-292.

The use of telemetry to refine experimental technique

Individual housing in mice was associated with significantly increased heart rate.

Year Published: 2000Animal Type: Mouse, Rodent

Citation: Einstein, R., Rowan, C., Billing, R. et al. 2000. The use of telemetry to refine experimental technique. In: Progress in the Reduction, Refinement and Replacement of Animal Experimentation. Balls, M., Van Zeller, A. M., Halder, M. E. (eds), 1187-1197. Elsevier, Amsterdam.

Use of a feeder insert to reduce obesity in rats

By inserting a modified stainless steel plate into the feeder, area of exposed food is reduced, and may result in increased exploratory activity, which may lead to decrease in body weights and food consumption values (all while continuing to provide...

Year Published: 2000Animal Type: Rat, Rodent

Citation: Van Berkum, L. E. 2000. Use of a feeder insert to reduce obesity in rats. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 125 (Abstract).

Improving the environment of mice by using synthetic gauze pads

The mice with gauze pads preferred to rest on them. In addition, these mice showed a statistically significant reduction in food consumption, but their body weights and weight gains did not differ from those of animals without gauze pads.

Year Published: 2000Animal Type: Mouse, Rodent

Citation: Smith, G. D., Hoffman, W. P., Lee, E. M. et al. 2000. Improving the environment of mice by using synthetic gauze pads . Contemporary Topics in Laboratory Animal Science 39(6), 51-53.

The Dalila effect:C57BL6 mice barber whiskers by plucking

Barbering is a common abnormal behavior in laboratory mice. Barbers hold down their cage mates, who adopt a defensive posture, and remove hair by plucking with their incisors. Once removed, the hair is often chewed by the barber. Although plucking...

Year Published: 2000Animal Type: Mouse, Rodent

Citation: Sarna, J. R., Dyck, R. H., Whishaw, I. Q. 2000. The Dalila effect:C57BL6 mice barber whiskers by plucking. Behavioural Brain Research 108, 39-45.

Preference of single housed rats for a solid-bottom or wire-bottom stainless steel cage floor

We modified a stainless steel multiple-animal wire-bottom cage by covering one-half of the floor surface with a solid plate of stainless steel [emphasis added]. .. At night, rats demonstrated a significant (P

Year Published: 2000Animal Type: Rat, Rodent

Citation: Rock, F. M., Jaslow, B. W., Peterson, A. et al. 2000. Preference of single housed rats for a solid-bottom or wire-bottom stainless steel cage floor. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 79 (Abstract).