Rodent

Assessing laboratory evidence for neoplastic activity

Mortality and tumor incidence in corcinogenesis experiments differ between mice caged in the top vs. bottom of the rack.

Year Published: 1980Topics: Housing, Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Mantel, N. 1980. Assessing laboratory evidence for neoplastic activity. Biometics 36, 381-399.

Discrimination of odours from stressed rats by non-stressed rats

Placing a rat into a new cage triggers release of corticosterones. This endocrine response is augmented if the new environment is one in which other rats had previously been subjected to stress.

Year Published: 1980Topics: Husbandry & ManagementAnimal Type: Rat, Rodent

Citation: Mackay-Sim, A., Laing, D. G. 1980. Discrimination of odours from stressed rats by non-stressed rats. Physiology and Behavior 24, 699-704.

Specific hormonal and neurochemical responses to different stressors

The neuroendocrine and neurochemical responses of rats to 5 min of cold exposure versus 5 min of forced immobilization were determined and compared. We found that plasma hormones and brain neurochemical systems responded differently to the two different stressors. Plasma...

Year Published: 1980Topics: RestraintAnimal Type: Rat, Rodent

Citation: Lenox, R. H., Kant, G. J., Sessions, G. R. et al. 1980. Specific hormonal and neurochemical responses to different stressors. Neuroendocrinology 30(5), 300-308.

Energetics of mice in stable and unstable social conditions: evidence of an air-borne factor affecting metabolism

Male mice kept individually have a 15% higher metabolic rate than mice kept in stable same gender pairs.

Year Published: 1980Topics: Social Housing & CompanionshipAnimal Type: Mouse, Rodent

Citation: Herreid, C. F., Schlenker, E. H. 1980. Energetics of mice in stable and unstable social conditions: evidence of an air-borne factor affecting metabolism. Animal Behaviour 28, 20-28.

Paradoxical sleep and memory (I): Selective alterations following enriched and impoverished environmental rearing

Mice were reared in either enriched (EE), social control, (SE), or impoverished (IE) environments for 30 days. Environmental enrichment results in a significant and selective increase in paradoxical sleep (PS, or REM sleep) and also enhances recall of a multiple-trial,...

Year Published: 1980Topics: Environmental Enrichment, Social Housing & CompanionshipAnimal Type: Mouse, Rodent

Citation: Gutwein, B. M., Fishbein, W. 1980. Paradoxical sleep and memory (I): Selective alterations following enriched and impoverished environmental rearing. Brain Research Bulletin 5(1), 9-12.

Stress response of rats to handling and experimental procedures

Serum corticosterone levels increased significantly within four minutes, reached a peak at 15 minutes and were back to control values 60 minutes after cage displacement. Prolactin, TSH, LH and FSH serum concentrations were also affected by cage movement. The results...

Year Published: 1980Topics: HandlingAnimal Type: Rat, Rodent

Citation: Gartner, K., Buttner, D., Dohler, R. et al. 1980. Stress response of rats to handling and experimental procedures. Laboratory Animals 14, 267-274.

Wheel-running behaviour in 12 species of muroid rodents

The objective of this research was to describe the levels and periodicity of wheel running in 12 species of muroid rodents in order that comparisons could be made among different measures of activity in a variety of species. Six males...

Year Published: 1980Animal Type: Mouse, Other Rodent, Rodent

Citation: Dewsbury, D. A. 1980. Wheel-running behaviour in 12 species of muroid rodents. Behavioural Processes 5, 271-280.

Peripheral nerve abnormalities in aging rats

Rats kept on wire-mesh flooring for a long time develop striking morphological changes in the distal sciatic/tibial/plantar never complex.

Year Published: 1981Animal Type: Rat, Rodent

Citation: Grover-Johnson, N., Spencer, P. S. 1981. Peripheral nerve abnormalities in aging rats. Journal of Neuropathology and Experimental Neurology 40, 155-165.

Nest-box choice in the laboratory mice: Preference for nest-boxes differing in design (size and/or shape) and composition

Mice had a strong preference for nest boxes which allowed visual cues to pass and which had a rectangular shape. Highest in order of preference were small narrow-sided nest-boxes, followed by small square ones, then the small circular one, and...

Year Published: 1981Animal Type: Mouse, Rodent

Citation: Buhot-Averseng, M. C. 1981. Nest-box choice in the laboratory mice: Preference for nest-boxes differing in design (size and/or shape) and composition. Behavioural Processes 6, 337-384.

Endogenous opioids and social behavior

Evidence for the hypothesis that brain-opioids mediate social affect and social attachments is summarized. Opiates and opioids are very effective in reducing social separation-induced distress vocalizations (DVs), in puppies, young guinea pigs and chicks, while opiate antagonists can increase DVs....

Year Published: 1980Topics: Social Housing & CompanionshipAnimal Type: Bird, Chicken, Dog, Guinea Pig, Mouse, Rat, Rodent

Citation: Panksepp, J., Herman, B. H., Vilberg, T. et al. 1980. Endogenous opioids and social behavior. Neuroscience and Biobehavioral Reviews 4(4), 473-487.