Miniaturized blood sampling techniques to benefit reduction in mice and refinement in nonhuman primates: Application to bioanalysis in toxicity studies with antibody-drug conjugates

Minimizing the number of animals in regulatory toxicity studies while achieving study objectives to support the development of future medicines contributes to good scientific and ethical practices. Recent advances in technology have enabled the development of miniaturized blood sampling methods...

Year Published: 2015Topics: Biological Sampling & Physiological MeasurementAnimal Type: Baboon, Capuchin, Chimpanzee, Lemur, Macaque, Marmoset, Mouse, Nonhuman Primate, Other Nonhuman Primate, Owl Monkey, Rodent, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Caron, A., Lelong, C., Pascual, M. H. et al. 2015. Miniaturized blood sampling techniques to benefit reduction in mice and refinement in nonhuman primates: Application to bioanalysis in toxicity studies with antibody-drug conjugates. JAALAS 54(2), 145-152.

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Effects of changing housing conditions on mangabey behavior (Cercocebus atys): Spatial density, housing quality, and novelty effects

The separate influences of spatial density and housing quality on the behavior of captive animals are difficult to measure because the two factors are often intrinsically linked. Here, we recorded affiliative and agonistic behavior in adult sooty mangabeys in various...

Year Published: 2015Topics: Environmental Enrichment, Housing, Stocking DensityAnimal Type: Nonhuman Primate, Other Nonhuman Primate

Citation: Crast, J., Bloomsmith, M. A., Jonesteller, T. 2015. Effects of changing housing conditions on mangabey behavior (Cercocebus atys): Spatial density, housing quality, and novelty effects. American Journal of Primatology 77(9), 1001-1014.

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