Mouse

Using obese mouse models in research: Special considerations for IACUC members, animal care technicians, and researchers

General discussion of husbandry issues specifically related to obese mice.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Good, D. J. 2005. Using obese mouse models in research: Special considerations for IACUC members, animal care technicians, and researchers. Lab Animal 34(2), 30-37.

A rapid, simple, and humane method for submandibular bleeding of mice using a lancet

Methods for obtaining blood samples frommicetend to be difficult, inhumane, or both. The authors describe an inexpensive, disposable, single-use lancet for submandibular bleeding ofmicethat allows investigators to quickly draw 0.2-0.5 ml of blood without the use of anesthesia.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Golde, W. T., Gollobin, P., Rodriguez, L. L. 2005. A rapid, simple, and humane method for submandibular bleeding of mice using a lancet. Lab Animal 34(9), 39-43.

Pair housing affects anxiety-like behaviors induced by a social but not by a physiological stressor in male Swiss mice

Pair housing proved to be effective in modulating anxiety-like behaviour.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Gasparotto, O. C., Lopes, D. M., Carobrez, S. G. 2005. Pair housing affects anxiety-like behaviors induced by a social but not by a physiological stressor in male Swiss mice. Physiology and Behavior 85(5), 603-612.

Rx for mice: Take enrichment and call me in the morning

In a first phase, the effectiveness of several enrichment devices was evaluated: flavored nylon chew bones, colored tunnels, igloo shaped houses, and a life-sized rubber mouse. Mice, whether alone or in a group, had constant interaction with the houses.... I...

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Gaskin, N. 2005. Rx for mice: Take enrichment and call me in the morning. Tech Talk [The Newsletter for Laboratory Animal Science Technicians] 10(6).

Effect of two types of environmental enrichment for singly housed mice on food intake and weight gain

Adult mice showed no change in either food intake or weight gain when an Igloo refuge was introduced into their cage.

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Robertson, K. L., Rowland, N. E. 2005. Effect of two types of environmental enrichment for singly housed mice on food intake and weight gain. Lab Animal 34(9), 29-32.

Assessment of the use of two commercially available environmental enrichments by laboratory mice by preference testing

All three strains of mice showed a significant preference for the paper box. The paper box was much lighter [20 g] than the plastic box [95 g]. This allowed the mice to move the paper box around, manipulate it and...

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Van Loo, P. L. P., Blom, H. J. M., Meijer, M. K. et al. 2005. Assessment of the use of two commercially available environmental enrichments by laboratory mice by preference testing. Laboratory Animals 39, 58-67.

Coping with aggression in group-housed male mice

Groups of three males have been found to show the least aggression because the dominance hierarchy is more stable than in larger groups. Pair housing can increase aggression and is more stressful to the subordinate because he will not receive...

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Van Loo, P. L. P. 2005. Coping with aggression in group-housed male mice. Animal Technology and Welfare 4, 84-86.

Impact of environmental enrichment in mice

The result of this study suggests that values of body weight, haematological variables .... were not significantly influenced by our enrichment design [nestbox plus climbing structure], but that enrichment seemed [sic] to have effects on the variation and the strain...

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Tsai, P. P., Pachowsky, U., Stelzer, H. D. et al. 2005. Impact of environmental enrichment in mice. 1: Effect of housing conditions on body weight, organ weights and haematology in different strains. Animal Technology and Welfare 4(1), 17-23.

Effects of housing density and cage floor space on three strains of young adult inbred mice

Some recommendations in the Guide for the Care and Use of Laboratory Animals (the Guide) are based on best professional judgment. Our current efforts are directed toward replacement with data-driven standards. We demonstrated earlier that young adult C57BL/6J mice could...

Year Published: 2005Topics: Housing, Stocking DensityAnimal Type: Mouse, Rodent

Citation: Smith, A. L., Mabus, S. L., Muir, C. et al. 2005. Effects of housing density and cage floor space on three strains of young adult inbred mice. Comparative Medicine 55(4), 368-376.

Modifications to husbandry and housing conditions of laboratory rodents for improved well-being

A review of the literature shows that a consensus on the definition of changes constituting environmental enrichment has yet to be reached. For this reason, the results of studies on the effects of rodent enrichment are inconsistent. In many cases,...

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Mouse, Rat, Rodent

Citation: Smith, A. L., Corrow, D. J. 2005. Modifications to husbandry and housing conditions of laboratory rodents for improved well-being. ILAR Journal 46(2), 140-147.