Mouse

Preparation of animals for research — Issues to consider for rodents and rabbits

This article provides details to consider when preparing to use animals in biomedical research. The stress of transport and receipt of animals into a new environment mandate the need for a period of stabilization and acclimation. This allotment of time...

Year Published: 2006Topics: Animal Training, Environmental Enrichment, Housing, Husbandry & Management, Regulations & Ethical Review, Relocation & Transport, Stocking DensityAnimal Type: Chinchilla, Gerbil, Guinea Pig, Hamster, Mouse, Other Rodent, Rabbit, Rat, Rodent

Citation: Conour, L. A., Murray, K. A., Brown, M. J. 2006. Preparation of animals for research -- Issues to consider for rodents and rabbits. ILAR Journal 47(4), 283-293.

The effects of environmental enrichment on nesting behaviour in a mouse model of Huntington’s disease

All mice in our colony are housed with some type of igloo or house from birth. In this study, WT and R6/2 male mice appear to build higher quality nests when housed without an igloo. One possible reason for this...

Year Published: 2006Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Burgen, P., Glynn, D., Morton, J. 2006. The effects of environmental enrichment on nesting behaviour in a mouse model of Huntington's disease. Animal Technology and Welfare 5(3), 147-152.

Environmental modification and agonistic behavior in NIH/S male mice: Nesting material enhances fighting but shelters prevent it

The aim of the study was to investigate effects of widely recommended nesting material and additional shelters on male mice. The aggressiveness of the mice in their home cages clearly increased in the nest group,as assessed by the number of...

Year Published: 2006Topics: Environmental Enrichment, HousingAnimal Type: Mouse, Rodent

Citation: Kaliste, E. K., Mering, S. M., Satu, M. et al. 2006. Environmental modification and agonistic behavior in NIH/S male mice: Nesting material enhances fighting but shelters prevent it. Comparative Medicine 56(3), 202-208.

The effects of rearing condition and enrichment on laboratory mouse immune response, health, and behavior

Animals in the enriched condition did have greater variation for any particular measurement (thymocyte populations).

Year Published: 2006Topics: Environmental Enrichment, Rearing & WeaningAnimal Type: Mouse, Rodent

Citation: Hutchinson, E. K., Avery, A., Van de Woude, S. 2006. The effects of rearing condition and enrichment on laboratory mouse immune response, health, and behavior. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 174 (Abstract).

A new concept for provision of water to mice

Problems associated with watering systems are discussed and a solution proposed.

Year Published: 2006Animal Type: Mouse, Rodent

Citation: Haida, D. 2006. A new concept for provision of water to mice. Animal Technology and Welfare 5, 41-43.

Behaviour of laboratory mice in different housing conditions when allowed to self-administer an anxiolytic

Standard cages prevent mice from performing several natural behaviours for which they are motivated. As a consequence, abnormal behaviours sometimes develop and mice often spend long periods inactive. To improve welfare, cages are sometimes furnished with items such as nesting...

Year Published: 2006Animal Type: Mouse, Rodent

Citation: Olsson, I. A. S., Sherwin, C. M. 2006. Behaviour of laboratory mice in different housing conditions when allowed to self-administer an anxiolytic . Laboratory Animals 40(4), 392-399.

Effects of humidity and environmental enrichment on food-chewing behavior in mice

Neither of the enrichment tools (Gumabones or a cellulose/corncob mixture) improved food-chewing behavior. As the humidity decreased over the 3-wk period, so did the abnormal behavior, regardless of the enrichment status of the cage.

Year Published: 2006Topics: Abnormal/Problematic Behavior, Environmental Enrichment, Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Nelson, C., Dysko, R. 2006. Effects of humidity and environmental enrichment on food-chewing behavior in mice. American Association for Laboratory Animal Science [AALAS] Meeting Official Program, 154 (Abstract).

Effect of restraint and injection methods on heart rate and body temperature in mice

It was found that heart rate (HR), and to a lesser extent also body temperature (BT), parallels plasma corticosterone (pCORT) values after subjecting the animals to different methods of restraint. Secondly, the acute stress response caused by different injection methods...

Year Published: 2006Topics: Drug/Substance Administration, RestraintAnimal Type: Mouse, Rodent

Citation: Meijer, M. K., Spruijt, B. M., van Zutphen, L. F. M. et al. 2006. Effect of restraint and injection methods on heart rate and body temperature in mice. Laboratory Animals 40(4), 82-391.

The effect of routine experimental procedures on physiological paramters in mice kept under different husbandry conditions

Single-housing in a non-enriched environment significantly elevated heart rate and blood pressure and recovery time following routine experimental procedures relative to social-housing in an enriched environment.

Year Published: 2006Animal Type: Mouse, Rodent

Citation: Meijer, M. K., Kramer, K., Remie, R. et al. 2006. The effect of routine experimental procedures on physiological paramters in mice kept under different husbandry conditions. Animal Welfare 15, 31-38.

Evaluation of five bedding types on male nude mouse health and aggression

From this study mice housed on thick corn cob appeared to show least aggression. Aspen chip seemed to increase aggression in male nudes.

Year Published: 2006Animal Type: Mouse, Rodent

Citation: Lawton, S., Taylor, V., Perks, V. 2006. Evaluation of five bedding types on male nude mouse health and aggression. Animal Technology and Welfare 5(3), 163-164.