Mouse

Environmental enrichment: room for reduction? Alternatives to Laboratory Animals (ATLA) 32(Supplement 2), 69-71

Environmental enrichment strategies are usually regarded as refinement. However, when the welfare of animals is enhanced through successful enrichment programmes, a reduction in the number of animals needed can be expected, because fewer animals might be lost during the course...

Year Published: 2004Topics: Environmental EnrichmentAnimal Type: All/General, Mouse, Rodent

Citation: Van de Weerd, H. A., Van Loo, P. L., Baumans. V. 2004. Environmental enrichment: room for reduction? Alternatives to Laboratory Animals (ATLA) 32(Supplement 2), 69-71.

Analyzing corticosterone metabolites in fecal samples of mice: a noninvasive technique to monitor stress

In small animals like mice, the monitoring of endocrine functions over time constrained seriously by the adverse effects of blood sampling. Therefore, techniques to monitor, for example, stress hormones in these animals are demanded in laboratory as well as in...

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Touma, C., Palme, R., Sachser, N. 2004. Analyzing corticosterone metabolites in fecal samples of mice: a noninvasive technique to monitor stress. Hormones and Behavior 45, 10-22.

Environmental options for laboratory rats and mice

Environmental enrichment is the alteration of animals' microenvironment to provide them with the opportunity to perform species-specific behaviors that we perceive as positive, while reducing abnormal behaviors. [p. 39] From my experience in providing environmental ernichment benefits for the animal,...

Year Published: 2004Animal Type: Mouse, Rat, Rodent

Citation: Key, D. 2004. Environmental options for laboratory rats and mice. Lab Animal 33(2), 39-44.

Housing, care and environmental factors

General discussion on husbandry and regulatory issues pertaining to the housing and care of laboratory animals.

Year Published: 2004Animal Type: All/General, Dog, Guinea Pig, Marmoset, Mouse, Nonhuman Primate, Pig, Rabbit, Rat, Rodent

Citation: Hansen, A. K. , Baumans, V. 2004. Housing, care and environmental factors. In: The Welfare of Laboratory Animals. Kaliste, E. (ed), 37-50. Kluwer Academic Publishers, Dordrecht, The Netherlands.

Water leakage in rodent cages: A discussion by the Laboratory Animal Refinement and Enrichment Forum

It is not uncommon that malfunctioning in watering valves or leaks of water bottles result in the accumulation of water in rodent cages (especially during holidays and on weekends), a circumstance that can have serious implications for the animals trapped...

Year Published: 2004Topics: Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Barley, J. B., Cherry, K. A., Garner, J. et al. 2004. Water leakage in rodent cages: A discussion by the Laboratory Animal Refinement and Enrichment Forum. Animal Technology and Welfare 3, 111-114.

Laboratory routines cause animal stress

Based on a literature review the conclusion was drawn that routine handling, venipuncture, and orogastic gavage lead to elevations of heart rate, blood pressure, and glucocorticoid concentrations that persist for 30 to 60 min or more following the event, suggesting...

Year Published: 2004Animal Type: All/General, Mouse, Nonhuman Primate, Rat, Rodent

Citation: Balcombe, J. P., Barnard, N. D., Sandusky, C. 2004. Laboratory routines cause animal stress. Contemporary Topics in Laboratory Animal Science 43(6), 42-51.

Environmental enrichment improves cognition in aged Alzheimer’s transgenic mice despite stable beta-amyloid deposition

Environmental enrichment (EE) has been shown to improve cognitive performance and brain indices of cognition in normal mice and rats. .. Beginning at 16 months of age, APPsw mice were put into EE or standard housing for 4 months and...

Year Published: 2004Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Arendash, G. W., Garcia, M. F., Costa, D. A. et al. 2004 . Environmental enrichment improves cognition in aged Alzheimer's transgenic mice despite stable beta-amyloid deposition. Neuroreport 15 , 1751-1754.

Environmental enrichment for laboratory rodents and rabbits: Requirements of rodents, rabbits, and research

Environmental conditions such as housing and husbandry have a major impact on the laboratory animal throughout its life and will thereby influence the outcome of animal experiments. However, housing systems for laboratory animals have often been designed on the basis...

Year Published: 2005Topics: Environmental EnrichmentAnimal Type: Gerbil, Guinea Pig, Hamster, Mouse, Rabbit, Rat, Rodent

Citation: Baumans, V. 2005. Environmental enrichment for laboratory rodents and rabbits: Requirements of rodents, rabbits, and research. ILAR Journal 46(2), 162-170.

Potential for unintended consequences of environmental enrihment for laboratory animals and research results

Many aspects of the research animal's housing environment are controlled for quality and/or standardization. Of recent interest is the potential for environmental enrichment to have unexpected consequences such as unintended harm to the animal, or the introduction of variability into...

Year Published: 2005Topics: Environmental Enrichment, Husbandry & Management, Social Housing & CompanionshipAnimal Type: Hamster, Macaque, Mouse, Nonhuman Primate, Rabbit, Rat, Rodent

Citation: Bayne, K. 2005. Potential for unintended consequences of environmental enrihment for laboratory animals and research results. ILAR Journal 46(2), 129-139.

Multiple housing of male CD-1 mice for toxicological studies

Aggression peaked around 10 weeks into the [10 months] study and was usually observed following dosing or cage cleaning, ceasing once human activities in the room were completed.

Year Published: 2005Animal Type: Mouse, Rodent

Citation: Bolam, S. 2005. Multiple housing of male CD-1 mice for toxicological studies. Animal Technology and Welfare 4, 86-87.