Mouse

New housing conditions: Improving the welfare of experimental animals

Prototypes for new housing systems satisfying the most important of these basic needs of the animals were developed. Along with newly introduced socialization programs [they] contribute to improved animal welfare. .. Mice need to be able to rest, hide and...

Year Published: 2004Animal Type: Dog, Guinea Pig, Mouse, Rabbit, Rat, Rodent

Citation: Ottesen, J. L., Weber, A., Gertler, H. et al. 2004. New housing conditions: Improving the welfare of experimental animals. Alternatives to Laboratory Animals [ATLA] 32(Supplement), 397-404.

Environmental enrichment for laboratory animals

Includes regulatory compliance, program development and management, common environmental enrichment strategies, program assessment and monitoring. A key component to the enrichment program development is the understanding of the natural behavior and habitat of each species housed in the animal facility....

Year Published: 2004Topics: Environmental EnrichmentAnimal Type: All/General, Baboon, Capuchin, Cat, Chimpanzee, Chinchilla, Dog, Ferret, Gerbil, Gibbon, Guinea Pig, Hamster, Lemur, Macaque, Marmoset, Mole Rat, Mouse, Nonhuman Primate, Other Nonhuman Primate, Other Rodent, Owl Monkey, Pig, Rabbit, Rat, Rodent, Sheep, Squirrel Monkey, Vervet (African Green Monkey)

Citation: Stewart, K. L. , Bayne, K. 2004. Environmental enrichment for laboratory animals. In: Laboratory Animal Medicine and Management. Reuter, J. D. , Suckow, M. A. (Eds). International Veterinary Information Service, Ithaca, New York.

Environmental enrichment rescues protetin deficits in a mouse model of Huntington’s disease, indicating a possible disease mechanism

These results suggest that environmental enrichment benefits animals at early stages of the disease by rescuing protein deficits, possibly through rescuing transcription or protein transport problems.

Year Published: 2004Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Spires, T. L., Grote, H. E., Varshney, N. K. et al. 2004. Environmental enrichment rescues protetin deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism. Journal of Neuroscience 24, 2270-2276.

Evaluation of cage micro-environment of mice housed on various types of bedding materials

A variety of environmental factors can affect the outcomes of studies using laboratory rodents. One such factor is bedding. Several new bedding materials and processing methods have been introduced to the market in recent years, but there are few reports...

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Smith, E., Stockwell, J. D., Schweitzer, I. et al. 2004. Evaluation of cage micro-environment of mice housed on various types of bedding materials. Journal of the American Association for Laboratory Animal Science [Contemporary Topics in Laboratory Animal Science] 43(4), 12-17.

Housing conditions affect self-administration of anxiolytic by laboratory mice

Standard cages for laboratory rodents may induce greater anxiety than enriched cages. Enriched mice drank significantly less of the midazolam solution than the non-enriched mice, suggesting that the combined effect of more space and enrichment made the animals less anxious.

Year Published: 2004Topics: Environmental Enrichment, HousingAnimal Type: Mouse, Rodent

Citation: Sherwin, C. M., Olsson, I. A. S. 2004. Housing conditions affect self-administration of anxiolytic by laboratory mice. Animal Welfare 13, 33-38.

Studies on the motivation for burrowing by laboratory mice

This study had two aims: (1) to investigate whether burrowing constitutes a behavioural need, that is, whether mice were motivated to perform the behaviour of burrowing per se, or whether it is the functional consequences of burrowing that motivate the...

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Sherwin, C. M., Haug, E., Terkelsen, V. et al. 2004. Studies on the motivation for burrowing by laboratory mice . Applied Animal Behaviour Science 88(3-4), 343-358.

Mirrors as potential environmental enrichment for individually housed laboratory mice

The present study examined the influence of a mirror on the behaviour individually housed laboratory mice. Sixteen mice were placed into apparatus comprised of preference cages connected by a tunnel. A mirror was placed in one of the preference (mirror)...

Year Published: 2004Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Sherwin, C. M. 2004. Mirrors as potential environmental enrichment for individually housed laboratory mice. Applied Animal Behaviour Science 87, 95-103.

The motivation of group-housed laboratory mice, Mus musculus, for additional space

The limited amount of space that we provide for research animals can adversely influence the validity of behavioural data and animal welfare. .. I trained a single mouse from each of six groups to perform an operant task to gain...

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Sherwin, C. M. 2004. The motivation of group-housed laboratory mice, Mus musculus, for additional space. Animal Behaviour 67, 711-717.

Enriched environment and acceleration of visual system development

Here, we examined Brain Derived Neurotrophic Factor (BDNF) levels in the visual cortex during development and showed that an increase occurs in the first week of life in enriched pups compared to standard reared pups. .. We found better learning...

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Sale, A., Putignano, E., Cancedda, L. et al. 2004. Enriched environment and acceleration of visual system development. Neuropharmacology 47, 649-660.

A better mouse cage

A closed-system caging with exhaust ventilation and environmental enrichment structures were studied. We conclude that this type of cages does refine mouse caging and might help reduce the number of mice used in biomedical research and testing.

Year Published: 2004Topics: HousingAnimal Type: Mouse, Rodent

Citation: Rivard, G. F., Pyle, K. C. 2004. A better mouse cage. Proceedings of the 4th World Congress on Alternatives and Animal Use in the Life Sciences - Alternatives to Laboratory Animals [ATLA] 32(Supplement), 98 (Abstract).