Mouse

Effect of enrichment on variation and results in the light/dark test

The aim of this study was to investigate if cage enrichment induces an effect on experimental mean values and on inter-individual variation in the light/dark paradigm using diazepam as the anxiolytic drug. The behaviour of 216 naive adult male mice...

Year Published: 2003Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Augustsson, H., Van de Weerd, H. A., Kruitwagen, C. L. J. J. et al. 2003. Effect of enrichment on variation and results in the light/dark test. Laboratory Animals 37, 328-251.

Husbandry refinements for rats, mice, dogs and non-human primates used in telemetry procedures

A review on telemetry procedures for rats, mice, dogs and non-human primates.

Year Published: 2004Animal Type: Dog, Mouse, Nonhuman Primate, Rat, Rodent

Citation: Hawkins, P., Morton, D. B., Bevan, R. et al. 2004. Husbandry refinements for rats, mice, dogs and non-human primates used in telemetry procedures. Laboratory Animals 38, 1-10.

Sex differences in psychological behavior changes induced by long-term social isolation in mice

Social isolation can induce psychological behavior changes. It is interesting to know whether there is sex difference in responding to social isolation or not. The present study compared the behavior difference between male and female mice isolated for 1-4 months....

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Guo, M., Wu, C. F., Liu, W. et al. 2004. Sex differences in psychological behavior changes induced by long-term social isolation in mice. Progress in Neuro-Psychopharmacology & Biological Psychiatry 28, 115-121.

Delayed onset of Huntington’s disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors

Our results therefore show that an enhanced environment slows the rate of loss of one of the first identifiable neurochemical deficits of HD. This suggests that delaying the loss of CB1 receptors, either by environmental stimulation or pharmacologically, may be...

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Glass, M., Van Dellen, A., Blakemore, C. et al. 2004. Delayed onset of Huntington's disease in mice in an enriched environment correlates with delayed loss of cannabinoid CB1 receptors. Neuroscience 123, 207-212.

Barbering (fur and whisker trimming) by laboratory mice as a model of human trichotillomania and obsessive-compulsive spectrum disorders

In a typical cage of barbered mice, all but one individual will have near-identical patterns of hair loss. The intact individual (the 'barber') is removing hair from its companions. .. Barbers hold down their cage mates [who adopt a defensive...

Year Published: 2004Topics: Abnormal/Problematic BehaviorAnimal Type: Mouse, Rodent

Citation: Garner, J. P., Weisker, S. M., Dufour, B. et al. 2004. Barbering (fur and whisker trimming) by laboratory mice as a model of human trichotillomania and obsessive-compulsive spectrum disorders. Comparative Medicine 54(2), 216-224.

Social and husbandry factors affecting the prevalence and severity of barbering (‘whisker trimming’) by laboratory mice

Barbering was found to be related to ... cage design, cage location, cagemate relatedness, and the presence of other barbers in the cage [social facilitiation]. .. The relative dominance score of a mouse within its cage was unrelated to barbering,...

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Garner, J. P., Dufour, B., Gregg, L. E. et al. 2004 . Social and husbandry factors affecting the prevalence and severity of barbering ('whisker trimming') by laboratory mice. Applied Animal Behaviour Science 89, 263-282.

Stress response in mice to a stressful situation experienced by another cage mate

We have just finished a study of the effects on cage mates when balb/c mice are handled/weighed or subjected to 1 hour restraint stress and then returned to the cage. We did this once daily for 14 days. The cage...

Year Published: 2004Topics: Emotion, Pain, & Sentience, Social Housing & CompanionshipAnimal Type: Mouse, Rodent

Citation: Einstein, R. 2004. Stress response in mice to a stressful situation experienced by another cage mate. Laboratory Animal Refinement and Enrichment Forum (electronic discussion group), November 24, 2004.

Implanted telemetry transmitters alter the noradreneigic response in vas deferens from mice

The results show that implantation of telemetry transmitters has a significant impact in mice that weigh

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Einstein, R., Billing, R. L., Singh, A. et al. 2004. Implanted telemetry transmitters alter the noradreneigic response in vas deferens from mice. Alternatives to Laboratory Animals [ATLA] 32(Supplement), 171-176.

From house mouse to mouse house: the behavioural biology of free-living Mus musculus and its implications in the laboratory

We review research and pest control literatures on the free-living house mouse (Mus musculus), analysing its sensory world, developmental processes and behaviour to suggest how laboratory environments might affect mouse welfare, normalcy, test design, and behaviour.

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Latham, N., Mason, G. 2004. From house mouse to mouse house: the behavioural biology of free-living Mus musculus and its implications in the laboratory. Applied Animal Behaviour Science 86, 261-289.

Effect of conditioning on the increase of heart rate and body temperature provoked by handling in the mouse

Handling and restraint of mice are common procedures in the laboratory animal house. The purpose of the present study was to investigate whether conditioning of mice with an acoustic stimulus (10kHz, 60dB), can reduce the stress effects of these routine...

Year Published: 2004Animal Type: Mouse, Rodent

Citation: Kramer, K., van de Weerd, H., Mulder, A. et al. 2004. Effect of conditioning on the increase of heart rate and body temperature provoked by handling in the mouse. Alternatives to Laboratory Animals [ATLA] 32(Supplement), 177-181.