Mouse

Barbering (whisker trimming) in laboratory mice involves the same brain systems as compulsive behaviors in trichotillomania, autism and other obsessive-compulsive spectrum disorders

Barbering appears to involve poor prefrontal cortex function.

Year Published: 2003Animal Type: Mouse, Rodent

Citation: Garner, J. P., Wayne, C. M., W?rbel, H. et al. 2003. Barbering (whisker trimming) in laboratory mice involves the same brain systems as compulsive behaviors in trichotillomania, autism and other obsessive-compulsive spectrum disorders. In: Proceedings of the International Congress on Applied Ethology. Ferrante, V. (ed), 75. Fondazione Iniziative Zooprofilattiche e Zootecniche, Abano Terme, Italy.

Enrichment enhances spatial memory and increases synaptophysin levels in aged female mice

Female C57BL/6 mice, (4 or 27-28 months), were tested in spatial and cued Morris water maze tasks. Prior to (14 days) and during testing, a subset of aged females was exposed to rodent toys and running wheels for 3h per...

Year Published: 2003Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Frick, K. M., Fernandez, S. M. 2003. Enrichment enhances spatial memory and increases synaptophysin levels in aged female mice. Neurobiology of Aging 24, 615-626.

Social conflict reduction program for male mice

At our Center, two observation periods were set aside daily in order to identify, according to previously described behaviors, dominant [aggressive] mice and separate these when indicated. By reducing or eliminating the number of aggressive acts between group members in...

Year Published: 2003Animal Type: Mouse, Rodent

Citation: Emond, M., Faubert, S., Perkins, M. 2003. Social conflict reduction program for male mice. Contemporary Topics in Laboratory Animal Science 42(5), 24-26.

Regional effects of wheel running and environmental enrichment on cell genesis and microglia proliferation in the adult murine neocortex

Voluntary wheel running, in contrast, caused an induction in the proliferation of microglia in superficial cortical layers of several brain regions.

Year Published: 2003Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Ehninger, D., Kempermann, G. 2003. Regional effects of wheel running and environmental enrichment on cell genesis and microglia proliferation in the adult murine neocortex. Cerebral Cortex 13, 845-851.

Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment

Pyramidal cells in environmentally enriched control animals were significantly more branched and more spinous than non-enriched controls. However, environmental enrichment had little effect on pyramidal cell structure in Ts65Dn mice.

Year Published: 2003Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Dierssen, M., Benavides-Piccione, R., Martinez-Cue, C. et al. 2003. Alterations of neocortical pyramidal cell phenotype in the Ts65Dn mouse model of Down syndrome: effects of environmental enrichment. Cerebral Cortex 13, 758-765.

Strain-specific aggressive behaviour of male mice submitted to different husbandry procedures

We used postcleaning aggressive behavior, wound counts, and testosterone levels as indicators of aggressiveness. .. Furthermore, the aggression-modulating effects of two enrichment items (ShepherdShack/DesRes and PVC tube) were explored. Marked differences found between the two strains. CD-1 mice were more...

Year Published: 2003Topics: Environmental Enrichment, Husbandry & ManagementAnimal Type: Mouse, Rodent

Citation: Van Loo, P. L. P., Van der Meer, E., Kruitwagen, C. L. J. J. et al. 2003. Strain-specific aggressive behaviour of male mice submitted to different husbandry procedures. Aggressive Behavior 29, 69-80.

Male management: coping with aggression problems in male laboratory mice

We review results from the literature and our own research with regard to coping with excessive aggressive behaviour in male laboratory mice. Based on this review practical recommendations concerning the housing and care of male laboratory mice are formulated. In...

Year Published: 2003Topics: Environmental Enrichment, Social Housing & CompanionshipAnimal Type: Mouse, Rodent

Citation: Van Loo, P. L. P., Van Zutphen, L. F. M., Baumans, V. 2003. Male management: coping with aggression problems in male laboratory mice. Laboratory Animals 37( ), 300-313.

Environmental enrichment: effects on stereotyped behavior and neurotrophin levels

These results provide evidence that the enrichment-related prevention of stereotyped behavior in deer mice is associated with increased BDNF in the striatum.

Year Published: 2003Topics: Abnormal/Problematic Behavior, Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Turner, C. A., Lewis, M. H. 2003. Environmental enrichment: effects on stereotyped behavior and neurotrophin levels. Physiology and Behavior 80, 259-266.

The effects of different rack systems on the breeding performance of DBA/2 mice

The presence of nesting material, a wood bar and a nest box was associated with a decrease in the number of pups born in mice kept in closed-system cages with exhaust ventilation

Year Published: 2003Animal Type: Mouse, Rodent

Citation: Tsai, P. P., Oppermann, D., Stelzer, H. D. et al. 2003. The effects of different rack systems on the breeding performance of DBA/2 mice. Laboratory Animals 37, 44-53.

Are the effects of different enrichment designs on the physiology and behaviour of DBA/2 mice consistent?

The present study focuses on the effects of different enrichment designs on the physiology and behaviour of male and female DBA/2 mice. .. Upon arrival at about 3 weeks of age, the animals were randomly allotted to three experimental groups:...

Year Published: 2003Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Tsai, P. P., Stelzer, H. D., Hedrich, H. J. et al. 2003. Are the effects of different enrichment designs on the physiology and behaviour of DBA/2 mice consistent? Laboratory Animals 37, 314-327.