Mouse

Floor space needs for laboratory mice: BALB/cJ males or females in solid-bottom cages with bedding

Studies were initiated to determine the effects of restricted (32.2 cm2 per mouse), normal (96.8 cm2), or excess floor space (129.0 cm2) allowances by using a model of three mice per cage. BALB/cJ mice were bred on-site and weaned at...

Year Published: 2001Animal Type: Mouse, Rodent

Citation: McGlone, J. J., Anderson, D. L., Norman, R. L. 2001. Floor space needs for laboratory mice: BALB/cJ males or females in solid-bottom cages with bedding. Contemporary Topics in Laboratory Animal Science 40(3), 21-25.

Escape behaviour in laboratory mice

Results suggest that mice chew at cage bars as an escape response rather than a functionless stereotypy or tooth growth control.

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Lewis, R. 2001. Escape behaviour in laboratory mice. Animal Technology 52, 38-39.

The use of radiotelemetry in small laboratory animals: Recent advances

Radiotelemetry provides an alternative means of obtaining physiological measurements from awake and freely moving laboratory animals, without introducing stress artifacts. For researchers, especially those in the fields of pharmacology and toxicology, the technique may provide a valuable tool for predicting...

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Kramer, K., Kinter, L., Brockway, B. et al. 2001. The use of radiotelemetry in small laboratory animals: Recent advances. Contemporary Topics in Laboratory Animal Science 40(1), 8-16.

Does conditioning influence the increase of heart rate and body temperature as provoked by handling in the mouse? Contemporary Topics in Laboratory Animal Science 40(4), 92 (Abstract)

Handling of mice or cleaning their cages results in an acute increase in heart rate (HR) and body temperature (BT). ... From the results it can be concluded that entering the animals' room even without performing handling procedures, increases HR...

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Kramer, K., Mulder, A., van de Weerd, H. et al. 2001. Does conditioning influence the increase of heart rate and body temperature as provoked by handling in the mouse? Contemporary Topics in Laboratory Animal Science 40(4), 92 (Abstract).

Report of the 2000 RSPCA/UFAW Rodent Welfare Group meeting

The following presentations are included in this database: A regulatory viewpoint on environmental stimulation in preclinical toxicology studies, by Jones D; Environmental enrichment for animals used in GLP [Good Laboratory Practice] toxicological studies, by Harding K; Escape behaviour in laboratory...

Year Published: 2001Animal Type: Mouse, Rat, Rodent

Citation: Hawkins, P., Berdoy, M., Deacon, R. et al. 2001. Report of the 2000 RSPCA/UFAW Rodent Welfare Group meeting. Animal Technology 52, 29-42.

Do male mice prefer or avoid each other’s company? Influence of hierarchy, kinship, and familiarity

Experiments that allowed male mice with different histories to choose either an inhabited or an empty cage have shown that the mice preferred the proximity [separated by wire mesh or Perspex wall with holes] of another male over individual housing....

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Van Loo, P. L. P., de Groot, A. C., Van Zuthpen, B. F. M. et al. 2001. Do male mice prefer or avoid each other's company? Influence of hierarchy, kinship, and familiarity. Journal of Applied Animal Welfare Science 4, 91-103.

Differential effects of enrichment on learning and memory function in NR2B transgenic mice

Our biochemical experiments showed that enrichment significantly increased protein levels of GluR1, NR2B, and NR2A subunits of glutamate receptors in both wild-type and NR2B Tg mice.

Year Published: 2001Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Tang, Y. P., Wang, H., Feng, R. et al. 2001. Differential effects of enrichment on learning and memory function in NR2B transgenic mice. Neuropharmacology 41, 779-790.

Environmental enrichment in BALB/c mice: effects in classical tests of anxiety and exposure to a predatory odor

Our results show that EC mice were more active than SC mice in the elevated plus maze and the open field. Thus, possibly as a direct consequence of frequent changes in their breeding conditions, reactivity to a novel environment was...

Year Published: 2001Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Roy, V., Belzung, C., Delarue, C. et al. 2001. Environmental enrichment in BALB/c mice: effects in classical tests of anxiety and exposure to a predatory odor. Physiology and Behavior 74, 313-320.

Environmental enrichment: effects on spatial memory and hippocampal CREB immunoreactivity

Environmental enrichment (particularly during the earlier period) improved performance on the Morris water maze and tended to increase immunoreactivity to CREB in the hippocampus.

Year Published: 2001Topics: Environmental EnrichmentAnimal Type: Mouse, Rodent

Citation: Williams, B. M., Luo, Y., Ward, C. et al. 2001. Environmental enrichment: effects on spatial memory and hippocampal CREB immunoreactivity. Physiology and Behavior 73, 649-658.

Modulation of aggression in male mice – Influence of group size and cage size

It is concluded that aggressive behaviour in group-housed male BALB/c mice is best prevented by housing the animals in small groups of three animals, while decreasing floor size per animal may be used as a temporary solution to decrease high...

Year Published: 2001Animal Type: Mouse, Rodent

Citation: Van Loo, P. L. P., Mol, J. A., Koolhaas, J. M. et al. 2001. Modulation of aggression in male mice - Influence of group size and cage size. Physiology and Behavior 72, 675-683.